TITINdb

Map SAVs to Structure

Position	Domain position	SAV	Structural Position	RS	Q(SASA)	Disease	Source	MAF
33689	1	V/A	1	None	0.1830	None	gnomAD-4.0.0	1.20032E-06
33690	2	P/S	2	None	0.0917	None	gnomAD-4.0.0	6.84201E-07
33691	3	D/E	3	rs1342398434	0.3105	None	gnomAD-2.1.1	4.02E-06
33691	3	D/E	3	rs1342398434	0.3105	None	gnomAD-4.0.0	3.18235E-06
33692	4	P/R	4	rs755832382	0.2791	None	gnomAD-2.1.1	4.02E-06
33692	4	P/R	4	rs755832382	0.2791	None	gnomAD-4.0.0	1.59118E-06
33694	6	R/K	6	rs747732590	0.2580	None	gnomAD-2.1.1	4.02E-06
33694	6	R/K	6	rs747732590	0.2580	None	gnomAD-3.1.2	6.57E-06
33694	6	R/K	6	rs747732590	0.2580	None	gnomAD-4.0.0	5.12394E-06
33694	6	R/T	6	rs747732590	0.2580	None	gnomAD-3.1.2	6.57E-06
33694	6	R/T	6	rs747732590	0.2580	None	gnomAD-4.0.0	6.57065E-06
33695	7	G/E	7	rs1553499879	0.3935	None	gnomAD-4.0.0	2.73678E-06
33697	9	K/T	11	rs1691033741	0.5990	None	gnomAD-4.0.0	1.20032E-06
33699	11	S/T	13	rs1691031638	0.3377	None	gnomAD-4.0.0	1.20032E-06
33700	12	D/G	14	None	0.7567	None	gnomAD-4.0.0	1.36839E-06
33700	12	D/H	14	rs878858552	0.7567	None	gnomAD-4.0.0	2.73678E-06
33700	12	D/N	14	None	0.7567	None	gnomAD-4.0.0	6.84194E-07
33701	13	V/I	15	rs754435284	0.2132	None	gnomAD-2.1.1	4.02E-06
33701	13	V/I	15	rs754435284	0.2132	None	gnomAD-3.1.2	6.57E-06
33701	13	V/I	15	rs754435284	0.2132	None	gnomAD-4.0.0	3.84281E-06
33702	14	S/P	16	rs751545599	0.3221	None	gnomAD-2.1.1	4.02E-06
33702	14	S/P	16	rs751545599	0.3221	None	gnomAD-4.0.0	1.59118E-06
33703	15	R/L	17	rs576025689	0.8785	None	gnomAD-4.0.0	1.3684E-06
33703	15	R/Q	17	rs576025689	0.8785	None	gnomAD-2.1.1	2.01E-05
33703	15	R/Q	17	rs576025689	0.8785	None	gnomAD-3.1.2	3.29E-05
33703	15	R/Q	17	rs576025689	0.8785	None	1000 genomes	1.99681E-04
33703	15	R/Q	17	rs576025689	0.8785	None	gnomAD-4.0.0	1.42517E-05
33704	16	D/E	18	None	0.2763	None	gnomAD-4.0.0	2.40064E-06
33706	18	V/A	20	rs1261733710	0.1056	None	gnomAD-2.1.1	4.02E-06
33706	18	V/A	20	rs1261733710	0.1056	None	gnomAD-4.0.0	3.60097E-06
33706	18	V/L	20	None	0.1056	None	gnomAD-4.0.0	1.20032E-06
33707	19	N/S	21	rs1691011936	0.3541	None	gnomAD-4.0.0	1.20032E-06
33709	21	T/I	23	None	0.4499	None	gnomAD-4.0.0	1.3684E-06
33709	21	T/K	23	None	0.4499	None	gnomAD-4.0.0	6.84201E-07
33711	23	T/I	25	rs1248094195	0.4326	None	gnomAD-2.1.1	4.02E-06
33711	23	T/S	25	None	0.4326	None	gnomAD-4.0.0	1.20032E-06
33712	24	E/D	26	rs1060503937	0.5951	None	gnomAD-2.1.1	4.02E-06
33712	24	E/D	26	rs1060503937	0.5951	None	gnomAD-4.0.0	6.84207E-07
33713	25	P/A	27	None	0.1033	None	gnomAD-4.0.0	6.84208E-07
33713	25	P/L	27	rs1317049640	0.1033	None	gnomAD-2.1.1	4.02E-06
33713	25	P/L	27	rs1317049640	0.1033	None	gnomAD-4.0.0	2.0526E-06
33713	25	P/S	27	None	0.1033	None	gnomAD-4.0.0	6.84208E-07
33714	26	A/T	28	rs776948324	0.4923	None	gnomAD-2.1.1	4.02E-06
33714	26	A/T	28	rs776948324	0.4923	None	gnomAD-4.0.0	1.23157E-05
33715	27	S/F	29	rs755892166	0.3228	None	gnomAD-2.1.1	1.21E-05
33715	27	S/F	29	rs755892166	0.3228	None	gnomAD-3.1.2	1.31E-05
33715	27	S/F	29	rs755892166	0.3228	None	gnomAD-4.0.0	1.11533E-05
33715	27	S/P	29	None	0.3228	None	gnomAD-4.0.0	1.20032E-06
33716	28	D/G	30	rs1300576084	0.2939	None	gnomAD-2.1.1	4.02E-06
33716	28	D/G	30	rs1300576084	0.2939	None	gnomAD-4.0.0	1.59115E-06
33716	28	D/N	30	None	0.2939	None	gnomAD-4.0.0	1.5912E-06
33718	30	G/S	32	rs760711365	0.5136	None	gnomAD-2.1.1	4.02E-06
33718	30	G/S	32	rs760711365	0.5136	None	gnomAD-4.0.0	1.59119E-06
33719	31	S/C	33	rs2154136682	0.1596	None	gnomAD-4.0.0	1.20032E-06
33720	32	K/R	34	rs727503535	0.8490	None	gnomAD-2.1.1	2.01E-05
33720	32	K/R	34	rs727503535	0.8490	None	gnomAD-4.0.0	9.54678E-06
33722	34	T/I	36	rs1372744849	0.4536	None	gnomAD-3.1.2	6.57E-06
33722	34	T/I	36	rs1372744849	0.4536	None	gnomAD-4.0.0	2.56195E-06
33722	34	T/S	36	None	0.4536	None	gnomAD-4.0.0	3.18234E-06
33724	36	Y/C	38	None	0.1199	None	gnomAD-4.0.0	1.20032E-06
33725	37	I/F	39	None	0.1622	None	gnomAD-4.0.0	6.84188E-07
33725	37	I/T	39	rs1329737429	0.1622	None	gnomAD-2.1.1	7.14E-06
33725	37	I/T	39	rs1329737429	0.1622	None	gnomAD-3.1.2	1.31E-05
33725	37	I/T	39	rs1329737429	0.1622	None	gnomAD-4.0.0	5.57685E-06
33725	37	I/V	39	rs878900245	0.1622	None	gnomAD-2.1.1	1.21E-05
33725	37	I/V	39	rs878900245	0.1622	None	gnomAD-3.1.2	6.57E-06
33725	37	I/V	39	rs878900245	0.1622	None	gnomAD-4.0.0	1.92088E-05
33726	38	V/A	40	None	0.0925	None	gnomAD-4.0.0	2.40064E-06
33728	40	K/N	42	None	0.1701	None	gnomAD-4.0.0	1.59125E-06
33728	40	K/T	42	None	0.1701	None	gnomAD-4.0.0	1.59115E-06
33729	41	C/Y	43	None	0.0659	None	gnomAD-4.0.0	1.59115E-06
33730	42	A/V	44	rs1690988435	0.1690	None	gnomAD-3.1.2	6.57E-06
33730	42	A/V	44	rs1690988435	0.1690	None	gnomAD-4.0.0	2.56211E-06
33731	43	T/A	50	rs746383312	0.3685	None	gnomAD-2.1.1	4.02E-06
33731	43	T/A	50	rs746383312	0.3685	None	gnomAD-4.0.0	1.20032E-06
33732	44	T/A	54	rs1690986189	0.5092	None	gnomAD-4.0.0	2.40064E-06
33732	44	T/I	54	rs1690985152	0.5092	None	gnomAD-3.1.2	6.57E-06
33732	44	T/I	54	rs1690985152	0.5092	None	gnomAD-4.0.0	2.56187E-06
33733	45	A/V	60	None	0.2924	None	gnomAD-4.0.0	3.18238E-06
33734	46	E/Q	63	None	0.7793	None	gnomAD-4.0.0	1.20032E-06
33737	49	L/F	66	rs1690979679	0.3049	None	gnomAD-4.0.0	1.20032E-06
33738	50	R/C	67	rs56273463	0.4597	None	gnomAD-2.1.1	5.62195E-03
33738	50	R/C	67	rs56273463	0.4597	None	gnomAD-3.1.2	5.99495E-03
33738	50	R/C	67	rs56273463	0.4597	None	1000 genomes	2.79553E-03
33738	50	R/C	67	rs56273463	0.4597	None	gnomAD-4.0.0	8.66767E-03
33738	50	R/H	67	rs192391568	0.4597	None	gnomAD-2.1.1	1.14138E-04
33738	50	R/H	67	rs192391568	0.4597	None	gnomAD-3.1.2	6.57E-05
33738	50	R/H	67	rs192391568	0.4597	None	1000 genomes	3.99361E-04
33738	50	R/H	67	rs192391568	0.4597	None	gnomAD-4.0.0	5.63842E-05
33738	50	R/S	67	None	0.4597	None	gnomAD-4.0.0	6.84197E-07
33740	52	G/R	69	rs536705240	0.1486	None	gnomAD-2.1.1	2.14E-05
33740	52	G/R	69	rs536705240	0.1486	None	gnomAD-3.1.2	5.91E-05
33740	52	G/R	69	rs536705240	0.1486	None	gnomAD-4.0.0	1.67297E-05
33741	53	Q/E	70	None	0.5015	None	gnomAD-4.0.0	6.84185E-07
33741	53	Q/H	70	rs754625556	0.5015	None	gnomAD-2.1.1	4.02E-06
33741	53	Q/H	70	rs754625556	0.5015	None	gnomAD-4.0.0	1.5911E-06
33743	55	R/L	83	None	0.8244	None	gnomAD-4.0.0	6.84183E-07
33743	55	R/Q	83	rs746547856	0.8244	None	gnomAD-2.1.1	7.13E-06
33743	55	R/Q	83	rs746547856	0.8244	None	gnomAD-3.1.2	1.31E-05
33743	55	R/Q	83	rs746547856	0.8244	None	gnomAD-4.0.0	1.1154E-05
33745	57	T/R	89	None	0.2572	None	gnomAD-4.0.0	1.20032E-06
33746	58	R/C	90	rs199594729	0.4556	None	gnomAD-2.1.1	1.61E-05
33746	58	R/C	90	rs199594729	0.4556	None	gnomAD-3.1.2	3.29E-05
33746	58	R/C	90	rs199594729	0.4556	None	gnomAD-4.0.0	9.91489E-06
33746	58	R/H	90	rs372584865	0.4556	None	gnomAD-2.1.1	1.61E-05
33746	58	R/H	90	rs372584865	0.4556	None	gnomAD-3.1.2	6.57E-06
33746	58	R/H	90	rs372584865	0.4556	None	gnomAD-4.0.0	1.61112E-05
33746	58	R/P	90	rs372584865	0.4556	None	gnomAD-3.1.2	6.57E-06
33746	58	R/P	90	rs372584865	0.4556	None	gnomAD-4.0.0	2.47865E-06
33747	59	Y/C	91	None	0.1857	None	gnomAD-4.0.0	1.20032E-06
33747	59	Y/H	91	rs1310463317	0.1857	None	gnomAD-2.1.1	4.02E-06
33747	59	Y/H	91	rs1310463317	0.1857	None	gnomAD-4.0.0	1.59108E-06
33748	60	T/I	92	rs750315507	0.3467	None	gnomAD-2.1.1	8.04E-06
33748	60	T/I	92	rs750315507	0.3467	None	gnomAD-4.0.0	1.36836E-06
33749	61	V/A	93	None	0.1213	None	gnomAD-4.0.0	1.20032E-06
33749	61	V/G	93	None	0.1213	None	gnomAD-4.0.0	1.20032E-06
33749	61	V/M	93	rs201554140	0.1213	None	gnomAD-2.1.1	7.92014E-04
33749	61	V/M	93	rs201554140	0.1213	None	gnomAD-3.1.2	2.01748E-03
33749	61	V/M	93	rs201554140	0.1213	None	1000 genomes	1.39776E-03
33749	61	V/M	93	rs201554140	0.1213	None	gnomAD-4.0.0	4.27539E-04
33750	62	I/F	94	rs1690954165	0.3104	None	gnomAD-4.0.0	6.3642E-06
33750	62	I/T	94	None	0.3104	None	gnomAD-4.0.0	1.36834E-06
33751	63	N/H	96	rs753658469	0.4822	None	gnomAD-2.1.1	2.85E-05
33751	63	N/H	96	rs753658469	0.4822	None	gnomAD-3.1.2	4.6E-05
33751	63	N/H	96	rs753658469	0.4822	None	gnomAD-4.0.0	2.78835E-05
33751	63	N/S	96	rs1475672598	0.4822	None	gnomAD-2.1.1	3.18E-05
33751	63	N/S	96	rs1475672598	0.4822	None	gnomAD-4.0.0	1.59107E-06
33753	65	F/C	98	None	0.6529	None	gnomAD-4.0.0	1.36835E-06
33753	65	F/S	98	rs764462637	0.6529	None	gnomAD-2.1.1	2.41E-05
33753	65	F/S	98	rs764462637	0.6529	None	gnomAD-4.0.0	9.57847E-06
33754	66	G/E	99	rs760939553	0.4894	None	gnomAD-2.1.1	8.04E-06
33754	66	G/E	99	rs760939553	0.4894	None	gnomAD-3.1.2	6.57E-06
33754	66	G/E	99	rs760939553	0.4894	None	gnomAD-4.0.0	1.859E-06
33755	67	K/E	100	None	1.1152	None	gnomAD-4.0.0	1.59111E-06
33757	69	S/N	103	rs1210718667	0.2347	None	gnomAD-2.1.1	3.19E-05
33757	69	S/N	103	rs1210718667	0.2347	None	gnomAD-3.1.2	6.57E-06
33757	69	S/N	103	rs1210718667	0.2347	None	gnomAD-4.0.0	6.57099E-06
33758	70	Y/H	104	None	0.2111	None	gnomAD-4.0.0	1.20032E-06
33760	72	F/I	106	None	0.1225	None	gnomAD-4.0.0	1.59109E-06
33760	72	F/L	106	None	0.1225	None	gnomAD-4.0.0	6.84183E-07
33761	73	R/Q	107	rs774790424	0.1472	None	gnomAD-2.1.1	2.14E-05
33761	73	R/Q	107	rs774790424	0.1472	None	gnomAD-3.1.2	1.97E-05
33761	73	R/Q	107	rs774790424	0.1472	None	gnomAD-4.0.0	1.23935E-05
33761	73	R/W	107	rs201421156	0.1472	None	gnomAD-2.1.1	9.27E-05
33761	73	R/W	107	rs201421156	0.1472	None	gnomAD-3.1.2	1.70915E-04
33761	73	R/W	107	rs201421156	0.1472	None	gnomAD-4.0.0	1.92103E-04
33762	74	V/I	108	rs1385559568	0.0748	None	gnomAD-3.1.2	6.57E-06
33762	74	V/I	108	rs1385559568	0.0748	None	gnomAD-4.0.0	2.47863E-06
33762	74	V/L	108	rs1385559568	0.0748	None	gnomAD-4.0.0	1.36837E-06
33763	75	I/T	109	rs1180167121	0.0926	None	gnomAD-2.1.1	4.02E-06
33763	75	I/T	109	rs1180167121	0.0926	None	gnomAD-4.0.0	6.8418E-06
33764	76	A/D	110	None	0.0668	None	gnomAD-2.1.1	7.13E-06
33764	76	A/D	110	None	0.0668	None	gnomAD-3.1.2	1.97E-05
33764	76	A/D	110	None	0.0668	None	gnomAD-4.0.0	1.97179E-05
33764	76	A/G	110	rs773542514	0.0668	None	gnomAD-2.1.1	1.21E-05
33764	76	A/G	110	rs773542514	0.0668	None	gnomAD-3.1.2	1.31E-05
33764	76	A/G	110	rs773542514	0.0668	None	gnomAD-4.0.0	9.91498E-06
33764	76	A/V	110	rs773542514	0.0668	None	gnomAD-2.1.1	4.64E-05
33764	76	A/V	110	rs773542514	0.0668	None	gnomAD-3.1.2	6.57E-05
33764	76	A/V	110	rs773542514	0.0668	None	gnomAD-4.0.0	9.85301E-05
33765	77	E/D	111	None	0.2934	None	gnomAD-4.0.0	2.40064E-06
33768	80	F/S	114	None	0.3762	None	gnomAD-4.0.0	2.40064E-06
33769	81	G/A	115	rs1553499045	0.1801	None	gnomAD-3.1.2	6.57E-06
33769	81	G/A	115	rs1553499045	0.1801	None	gnomAD-4.0.0	6.57315E-06
33769	81	G/C	115	rs1690932780	0.1801	None	gnomAD-3.1.2	6.57E-06
33769	81	G/C	115	rs1690932780	0.1801	None	gnomAD-4.0.0	6.57246E-06
33769	81	G/S	115	rs1690932780	0.1801	None	gnomAD-4.0.0	1.20032E-06
33771	83	S/C	118	None	0.0837	None	gnomAD-4.0.0	2.73672E-06
33771	83	S/R	118	None	0.0837	None	gnomAD-4.0.0	7.20193E-06
33772	84	K/E	119	rs1362410602	0.8842	None	gnomAD-3.1.2	6.57E-06
33772	84	K/E	119	rs1362410602	0.8842	None	gnomAD-4.0.0	2.56176E-06
33772	84	K/N	119	rs1255240121	0.8842	None	gnomAD-4.0.0	3.18225E-06
33773	85	P/S	120	rs768248494	0.3441	None	gnomAD-2.1.1	4.02E-06
33773	85	P/S	120	rs768248494	0.3441	None	gnomAD-4.0.0	1.59118E-06
33775	87	E/G	122	None	0.8080	None	gnomAD-4.0.0	1.59109E-06
33776	88	P/A	123	rs746665837	0.3448	None	gnomAD-2.1.1	8.03E-06
33776	88	P/A	123	rs746665837	0.3448	None	gnomAD-3.1.2	6.57E-06
33776	88	P/A	123	rs746665837	0.3448	None	gnomAD-4.0.0	5.57713E-06
33776	88	P/L	123	rs536357517	0.3448	None	gnomAD-2.1.1	8.03E-06
33776	88	P/L	123	rs536357517	0.3448	None	gnomAD-3.1.2	2.63E-05
33776	88	P/L	123	rs536357517	0.3448	None	1000 genomes	1.99681E-04
33776	88	P/L	123	rs536357517	0.3448	None	gnomAD-4.0.0	3.71775E-06
33777	89	S/L	124	rs983842520	0.1445	None	gnomAD-3.1.2	1.31E-05
33777	89	S/L	124	rs983842520	0.1445	None	gnomAD-4.0.0	4.05978E-06
33778	90	E/K	125	None	0.6441	None	gnomAD-4.0.0	1.20032E-06
33779	91	P/S	126	rs1690922403	0.3238	None	gnomAD-3.1.2	6.57E-06
33779	91	P/S	126	rs1690922403	0.3238	None	gnomAD-4.0.0	3.84316E-06
33780	92	T/I	127	rs2154136558	0.2066	None	gnomAD-4.0.0	1.36835E-06
33781	93	I/V	128	rs1029128193	0.3439	None	gnomAD-4.0.0	4.77324E-06
33782	94	T/I	130	rs771566432	0.2137	None	gnomAD-2.1.1	3.18E-05
33782	94	T/I	130	rs771566432	0.2137	None	gnomAD-3.1.2	1.97E-05
33782	94	T/I	130	rs771566432	0.2137	None	gnomAD-4.0.0	4.33779E-06
33782	94	T/S	130	rs771566432	0.2137	None	gnomAD-4.0.0	6.84174E-07
33783	95	K/R	131	None	0.7392	None	gnomAD-4.0.0	1.59107E-06
33784	96	E/Q	132	rs918368881	0.3299	None	gnomAD-2.1.1	3.18E-05
33784	96	E/Q	132	rs918368881	0.3299	None	gnomAD-3.1.2	1.31E-05
33784	96	E/Q	132	rs918368881	0.3299	None	gnomAD-4.0.0	1.31453E-05

Position	Domain position	SAV	RS	Q(SASA)	Source	Structural Position	Disease	AlphaMissense (IC)	AlphaMissense (N2AB)	CADD	Condel	DUET	FATHMM	M-CAP	mCSM	MetaLR	MetaSVM	MPC	MutationAssessor	MutationTaster	MutPred	MVP	PolyPhen-2	PrimateAI	PROVEAN	REVEL	Rhapsody	SIFT	Zygosity	Comments	MAF	AFR	AMR	AMS	ASJ	EAS	EUR	FIN	MDE	NFE	SAS	OTH	Site Annotation	Predicted PPI	mCSM-PPI
33689	1	V/A	None	0.1830	gnomAD-4.0.0	1	None	0.4478	0.3463	34.0	N	None	1.06	0.031697	-0.648	0.203	-0.7397	0.378906110955	1.195	0.999972	0.359	0.491928505054	0.995	0.784716963768	-2.67	0.231	0.385	0.251	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
33690	2	P/S	None	0.0917	gnomAD-4.0.0	2	None	0.9906	0.9848	33.0	D	None	-1.86	0.141778	-2.253	0.8375	0.8723	0.466031226403	3.075	1.0	0.771	0.729836406417	1.0	0.757317364216	-6.93	0.781	0.745	None	None	None	6.84201E-07	0	0	0	0	None	0	0	6.84201E-07	8.99447E-07	0	0	None	N	None
33691	3	D/E	rs1342398434	0.3105	gnomAD-2.1.1	3	None	0.3628	0.303	26.3	N	-0.733	0.37	0.02527	-0.826	0.1326	-0.9152	0.0840408096913	1.515	0.955884	0.485	0.190952846119	0.12	0.559974610806	-3.38	0.114	0.485	0.025	None	None	4.02E-06	0	0	0	0	None	0	None	4.02E-06	0	8.87E-06	0	None	N	None
33691	3	D/E	rs1342398434	0.3105	gnomAD-4.0.0	3	None	0.3628	0.303	26.3	N	-0.733	0.37	0.02527	-0.826	0.1326	-0.9152	0.0840408096913	1.515	0.955884	0.485	0.190952846119	0.12	0.559974610806	-3.38	0.114	0.485	0.025	None	None	3.18235E-06	0	0	0	0	None	0	0	3.18235E-06	5.71595E-06	0	0	None	N	None
33692	4	P/R	rs755832382	0.2791	gnomAD-2.1.1	4	None	0.6338	0.5282	35.0	N	-0.729	0.29	0.050396	-0.72	0.3837	-0.2288	0.37650689494	2.36	0.999999	0.554	0.60087810649	0.973	0.644341349602	-7.6	0.418	0.867	0.002	None	None	4.02E-06	0	0	0	0	None	0	None	4.02E-06	0	0	1.65618E-04	None	N	None
33692	4	P/R	rs755832382	0.2791	gnomAD-4.0.0	4	None	0.6338	0.5282	35.0	N	-0.729	0.29	0.050396	-0.72	0.3837	-0.2288	0.37650689494	2.36	0.999999	0.554	0.60087810649	0.973	0.644341349602	-7.6	0.418	0.867	0.002	None	None	1.59118E-06	0	0	0	0	None	0	2.41196E-04	1.59118E-06	0	0	0	None	N	None
33694	6	R/K	rs747732590	0.2580	gnomAD-2.1.1	6	None	0.0972	0.1	24.4	N	-0.321	0.38	0.036271	-0.532	0.1545	-0.8656	0.0891610827172	0.89	0.909609	0.501	0.264547087235	0.048	0.64659178257	-2.0	0.146	0.202	0.472	None	None	4.02E-06	0	0	0	0	None	0	None	4.02E-06	0	8.87E-06	0	None	N	None
33694	6	R/K	rs747732590	0.2580	gnomAD-3.1.2	6	None	0.0972	0.1	24.4	N	-0.321	0.38	0.036271	-0.532	0.1545	-0.8656	0.0891610827172	0.89	0.909609	0.501	0.264547087235	0.048	0.64659178257	-2.0	0.146	0.202	0.472	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	N	None
33694	6	R/K	rs747732590	0.2580	gnomAD-4.0.0	6	None	0.0972	0.1	24.4	N	-0.321	0.38	0.036271	-0.532	0.1545	-0.8656	0.0891610827172	0.89	0.909609	0.501	0.264547087235	0.048	0.64659178257	-2.0	0.146	0.202	0.472	None	None	5.12394E-06	1.69125E-05	0	0	0	None	0	0	5.12394E-06	4.78556E-06	0	2.84398E-05	None	N	None
33694	6	R/T	rs747732590	0.2580	gnomAD-3.1.2	6	None	0.2559	0.2218	27.7	N	None	0.45	0.063542	-0.425	0.2417	-0.6334	0.4042939334	0.46	0.985563	0.421	0.568072681961	0.993	0.631069242954	-4.75	0.288	0.715	0.042	None	None	6.57E-06	0	6.55E-05	0	0	None	0	0	6.57E-06	0	0	0	None	N	None
33694	6	R/T	rs747732590	0.2580	gnomAD-4.0.0	6	None	0.2559	0.2218	27.7	N	None	0.45	0.063542	-0.425	0.2417	-0.6334	0.4042939334	0.46	0.985563	0.421	0.568072681961	0.993	0.631069242954	-4.75	0.288	0.715	0.042	None	None	6.57065E-06	0	6.54707E-05	0	0	None	0	0	6.57065E-06	0	0	0	None	N	None
33695	7	G/E	rs1553499879	0.3935	gnomAD-4.0.0	7	None	0.248	0.2279	34.0	N	None	0.38	0.045529	-0.704	0.2618	-0.5806	0.519446559066	0.475	0.99998	0.485	0.401327265625	1.0	0.76799595356	-4.32	0.285	0.819	0.129	None	None	2.73678E-06	0	0	0	0	None	0	0	2.73678E-06	2.69833E-06	1.15934E-05	0	None	N	None
33697	9	K/T	rs1691033741	0.5990	gnomAD-4.0.0	11	None	0.1124	0.1373	34.0	N	None	0.45	0.042874	-0.179	0.1915	-0.7136	0.304964859574	-0.115	0.985268	0.46	0.280181792013	0.78	0.730986237526	-4.1	0.179	0.585	0.155	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
33699	11	S/T	rs1691031638	0.3377	gnomAD-4.0.0	13	None	0.0691	0.0739	25.5	N	None	0.39	0.022993	-0.528	0.1365	-0.9401	0.0773877006654	-0.27	0.963477	0.337	0.17258766438	0.004	0.683677911758	-1.87	0.072	0.195	0.423	None	None	1.20032E-06	6.33473E-05	0	0	0	None	0	0	1.20032E-06	0	0	0	None	N	None
33700	12	D/G	None	0.7567	gnomAD-4.0.0	14	None	0.454	0.3595	35.0	N	None	0.38	0.04503	-0.284	0.2257	-0.621	0.232345094016	2.015	0.999999	0.565	0.283761946502	0.557	0.568510353565	-5.0	0.334	0.569	0.057	None	None	1.36839E-06	0	0	0	0	None	0	0	1.36839E-06	1.79888E-06	0	0	None	N	None
33700	12	D/H	rs878858552	0.7567	gnomAD-4.0.0	14	None	0.668	0.6205	33.0	N	None	0.3	0.035517	0.059	0.3301	-0.3765	0.36103451982	2.39	1.0	0.553	0.333906830038	0.984	0.645964622498	-4.92	0.404	0.586	0.004	None	None	2.73678E-06	0	0	0	0	None	0	0	2.73678E-06	3.59776E-06	0	0	None	N	None
33700	12	D/N	None	0.7567	gnomAD-4.0.0	14	None	0.1897	0.1752	27.5	N	None	0.44	0.058954	0.319	0.1465	-0.8755	0.136780165506	1.255	1.0	0.569	0.208816687407	0.436	0.621157109737	-3.0	0.233	0.539	0.043	None	None	6.84194E-07	0	0	0	0	None	0	0	6.84194E-07	0	0	1.65662E-05	None	N	None
33701	13	V/I	rs754435284	0.2132	gnomAD-2.1.1	15	None	0.0721	0.0742	22.9	N	-0.58	0.4	0.005555	-0.602	0.0905	-0.9988	0.0686030123765	1.075	0.858278	0.494	0.305410167561	None	0.46316421032	-0.44	0.083	0.143	0.335	None	None	4.02E-06	0	0	0	0	None	3.27E-05	None	4.02E-06	0	0	0	None	N	None
33701	13	V/I	rs754435284	0.2132	gnomAD-3.1.2	15	None	0.0721	0.0742	22.9	N	-0.58	0.4	0.005555	-0.602	0.0905	-0.9988	0.0686030123765	1.075	0.858278	0.494	0.305410167561	None	0.46316421032	-0.44	0.083	0.143	0.335	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	N	None
33701	13	V/I	rs754435284	0.2132	gnomAD-4.0.0	15	None	0.0721	0.0742	22.9	N	-0.58	0.4	0.005555	-0.602	0.0905	-0.9988	0.0686030123765	1.075	0.858278	0.494	0.305410167561	None	0.46316421032	-0.44	0.083	0.143	0.335	None	None	3.84281E-06	1.69102E-05	0	0	0	None	0	0	3.84281E-06	0	2.67989E-05	0	None	N	None
33702	14	S/P	rs751545599	0.3221	gnomAD-2.1.1	16	None	0.9631	0.9322	27.3	N	-0.562	0.02	0.059353	-0.402	0.3659	-0.2491	0.378805878549	2.44	0.999228	0.571	0.277730125212	0.932	0.621907353401	-3.55	0.4	0.448	0.012	None	None	4.02E-06	0	0	0	0	None	0	None	4.02E-06	0	8.88E-06	0	None	N	None
33702	14	S/P	rs751545599	0.3221	gnomAD-4.0.0	16	None	0.9631	0.9322	27.3	N	-0.562	0.02	0.059353	-0.402	0.3659	-0.2491	0.378805878549	2.44	0.999228	0.571	0.277730125212	0.932	0.621907353401	-3.55	0.4	0.448	0.012	None	None	1.59118E-06	0	0	0	0	None	0	0	1.59118E-06	2.85801E-06	0	0	None	N	None
33703	15	R/L	rs576025689	0.8785	gnomAD-4.0.0	17	None	0.8961	0.7839	32.0	N	None	0.42	0.028033	-0.388	0.3509	-0.3774	0.511382231021	1.075	0.999999	0.542	0.519187973786	1.0	0.665213108063	-5.17	0.416	0.667	0.016	None	None	1.3684E-06	2.98793E-05	0	0	0	None	0	0	1.3684E-06	0	1.15937E-05	0	None	N	None
33703	15	R/Q	rs576025689	0.8785	gnomAD-2.1.1	17	None	0.5309	0.3777	None	N	-0.538	None	None	-0.587	None	None	None	None	None	None	None	1.0	None	None	0.251	0.737	None	None	None	2.01E-05	1.29182E-04	0	0	0	None	6.54E-05	None	2.01E-05	0	8.88E-06	0	None	N	None
33703	15	R/Q	rs576025689	0.8785	gnomAD-3.1.2	17	None	0.5309	0.3777	None	N	-0.538	None	None	-0.587	None	None	None	None	None	None	None	1.0	None	None	0.251	0.737	None	None	None	3.29E-05	4.83E-05	0	0	0	None	0	0	3.29E-05	2.94E-05	2.07125E-04	0	None	N	None
33703	15	R/Q	rs576025689	0.8785	1000 genomes	17	None	0.5309	0.3777	None	N	-0.538	None	None	-0.587	None	None	None	None	None	None	None	1.0	None	None	0.251	0.737	None	None	None	1.99681E-04	0	0	None	0	0	None	None	1.99681E-04	None	1E-03	None	None	N	None
33703	15	R/Q	rs576025689	0.8785	gnomAD-4.0.0	17	None	0.5309	0.3777	None	N	-0.538	None	None	-0.587	None	None	None	None	None	None	None	1.0	None	None	0.251	0.737	None	None	None	1.42517E-05	5.33134E-05	0	0	0	None	0	0	1.42517E-05	1.0171E-05	6.58776E-05	1.60056E-05	None	N	None
33704	16	D/E	None	0.2763	gnomAD-4.0.0	18	None	0.8443	0.7316	33.0	N	None	0.36	0.020862	-0.564	0.1821	-0.8251	0.438398937775	1.215	0.97522	0.417	0.322510055762	0.994	0.724017977715	-3.33	0.187	0.47	0.166	None	None	2.40064E-06	0	0	0	0	None	0	0	2.40064E-06	2.625E-06	0	0	None	N	None
33706	18	V/A	rs1261733710	0.1056	gnomAD-2.1.1	20	None	0.5748	0.5299	29.7	N	-2.657	0.3	0.035144	-2.315	0.1599	-0.893	0.105728612331	1.495	0.99616	0.619	0.316494231283	0.005	0.693749070168	-2.97	0.141	0.374	0.209	None	None	4.02E-06	0	0	0	0	None	0	None	4.02E-06	0	8.88E-06	0	None	N	None
33706	18	V/A	rs1261733710	0.1056	gnomAD-4.0.0	20	None	0.5748	0.5299	29.7	N	-2.657	0.3	0.035144	-2.315	0.1599	-0.893	0.105728612331	1.495	0.99616	0.619	0.316494231283	0.005	0.693749070168	-2.97	0.141	0.374	0.209	None	None	3.60097E-06	0	0	0	0	None	0	0	3.60097E-06	3.9375E-06	0	0	None	N	None
33706	18	V/L	None	0.1056	gnomAD-4.0.0	20	None	0.5112	0.4548	24.0	N	None	0.6	0.073008	-0.836	0.1686	-0.8812	0.090661905353	1.875	0.998825	0.454	0.278968121808	0.107	0.679245948792	-1.5	0.09	0.523	0.157	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
33707	19	N/S	rs1691011936	0.3541	gnomAD-4.0.0	21	None	0.0807	0.0836	28.1	N	None	0.53	0.024427	-0.936	0.1065	-0.9579	0.0739716736363	-0.08	0.927524	0.312	0.154104182512	0.13	0.552637040615	-2.3	0.117	0.299	0.736	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
33709	21	T/I	None	0.4499	gnomAD-4.0.0	23	None	0.1623	0.1446	34.0	N	None	0.29	0.029694	0.04	0.3502	-0.247	0.389484333747	1.935	0.813375	0.475	0.377274123778	0.995	0.612846255302	-4.58	0.293	0.551	0.007	None	None	1.3684E-06	0	0	0	0	None	0	0	1.3684E-06	1.79888E-06	0	0	None	N	None
33709	21	T/K	None	0.4499	gnomAD-4.0.0	23	None	0.3224	0.3154	28.7	N	None	0.38	0.035577	-0.469	0.1125	-0.8405	0.169511622479	1.125	0.888731	0.548	0.284539287134	0.965	0.584138154984	-4.1	0.237	0.407	0.04	None	None	6.84201E-07	0	0	0	0	None	0	0	6.84201E-07	8.99442E-07	0	0	None	N	None
33711	23	T/I	rs1248094195	0.4326	gnomAD-2.1.1	25	None	0.1359	0.1361	25.7	N	0.06	0.29	0.028261	-0.202	0.1306	-0.9503	0.0901266826449	1.095	0.949795	0.478	0.202086224978	0.001	0.404541194439	-3.03	0.142	0.188	0.089	None	None	4.02E-06	0	0	0	0	None	0	None	4.02E-06	0	8.88E-06	0	None	N	None
33711	23	T/S	None	0.4326	gnomAD-4.0.0	25	None	0.104	0.1109	25.1	N	None	0.47	0.015213	-1.152	0.0821	-1.0384	0.0754831300525	-0.105	0.995408	0.282	0.134241683229	0.003	0.342932879925	-1.85	0.073	0.213	0.343	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
33712	24	E/D	rs1060503937	0.5951	gnomAD-2.1.1	26	None	0.2254	0.2476	23.9	N	-0.864	0.36	0.021574	-1.255	0.1357	-0.8987	0.0764562275565	1.9	0.964351	0.341	0.221734844693	0.062	0.330295532942	-1.89	0.042	0.492	0.161	None	None	4.02E-06	0	0	0	0	None	3.27E-05	None	4.02E-06	0	0	0	None	N	None
33712	24	E/D	rs1060503937	0.5951	gnomAD-4.0.0	26	None	0.2254	0.2476	23.9	N	-0.864	0.36	0.021574	-1.255	0.1357	-0.8987	0.0764562275565	1.9	0.964351	0.341	0.221734844693	0.062	0.330295532942	-1.89	0.042	0.492	0.161	None	None	6.84207E-07	0	0	0	0	None	0	0	6.84207E-07	0	1.15931E-05	0	None	N	None
33713	25	P/A	None	0.1033	gnomAD-4.0.0	27	None	0.6966	0.6709	26.1	N	None	-0.44	0.065807	-2.09	0.3695	-0.3208	0.092991018649	3.285	0.999993	0.75	0.309530620856	0.04	0.544542193413	-6.93	0.589	0.508	None	None	None	6.84208E-07	0	0	0	0	None	0	0	6.84208E-07	8.9945E-07	0	0	None	N	None
33713	25	P/L	rs1317049640	0.1033	gnomAD-2.1.1	27	None	0.9501	0.9347	35.0	D	-0.771	-0.44	0.073959	-0.965	0.6098	0.4128	0.441673272743	3.455	1.0	0.753	0.767357779069	0.997	0.616455197334	-8.53	0.677	0.872	None	None	None	4.02E-06	0	0	0	0	None	0	None	4.02E-06	0	8.88E-06	0	None	N	None
33713	25	P/L	rs1317049640	0.1033	gnomAD-4.0.0	27	None	0.9501	0.9347	35.0	D	-0.771	-0.44	0.073959	-0.965	0.6098	0.4128	0.441673272743	3.455	1.0	0.753	0.767357779069	0.997	0.616455197334	-8.53	0.677	0.872	None	None	None	2.0526E-06	0	0	0	0	None	0	0	2.0526E-06	2.69834E-06	0	0	None	N	None
33713	25	P/S	None	0.1033	gnomAD-4.0.0	27	None	0.9482	0.9376	33.0	N	None	-0.44	0.067269	-2.477	0.4446	0.0022	0.372327555718	1.905	0.999996	0.717	0.438383285633	0.988	0.554235160351	-6.93	0.637	0.765	None	None	None	6.84208E-07	0	0	0	0	None	0	0	6.84208E-07	8.9945E-07	0	0	None	N	None
33714	26	A/T	rs776948324	0.4923	gnomAD-2.1.1	28	None	0.0861	0.085	29.4	N	-0.148	0.43	0.033514	-0.498	0.2869	-0.544	0.455561052651	0.69	1.0	0.352	0.337135696972	0.999	0.555828928947	-2.73	0.216	0.682	0.124	None	None	4.02E-06	0	0	0	0	None	3.27E-05	None	4.02E-06	0	0	0	None	N	None
33714	26	A/T	rs776948324	0.4923	gnomAD-4.0.0	28	None	0.0861	0.085	29.4	N	-0.148	0.43	0.033514	-0.498	0.2869	-0.544	0.455561052651	0.69	1.0	0.352	0.337135696972	0.999	0.555828928947	-2.73	0.216	0.682	0.124	None	None	1.23157E-05	0	0	0	0	None	0	0	1.23157E-05	1.43912E-05	1.15931E-05	1.65645E-05	None	N	None
33715	27	S/F	rs755892166	0.3228	gnomAD-2.1.1	29	None	0.2021	0.1832	33.0	N	-1.035	0.18	0.056623	-1.118	0.1799	-0.5741	0.150557802847	0.725	0.521398	0.514	0.404733080969	0.667	0.50227868557	-3.2	0.169	0.47	0.072	None	None	1.21E-05	0	0	0	0	None	0	None	1.21E-05	0	2.66E-05	0	None	N	None
33715	27	S/F	rs755892166	0.3228	gnomAD-3.1.2	29	None	0.2021	0.1832	33.0	N	-1.035	0.18	0.056623	-1.118	0.1799	-0.5741	0.150557802847	0.725	0.521398	0.514	0.404733080969	0.667	0.50227868557	-3.2	0.169	0.47	0.072	None	None	1.31E-05	0	0	0	0	None	0	0	1.31E-05	2.94E-05	0	0	None	N	None
33715	27	S/F	rs755892166	0.3228	gnomAD-4.0.0	29	None	0.2021	0.1832	33.0	N	-1.035	0.18	0.056623	-1.118	0.1799	-0.5741	0.150557802847	0.725	0.521398	0.514	0.404733080969	0.667	0.50227868557	-3.2	0.169	0.47	0.072	None	None	1.11533E-05	0	0	0	0	None	0	0	1.11533E-05	1.44088E-05	0	1.60041E-05	None	N	None
33715	27	S/P	None	0.3228	gnomAD-4.0.0	29	None	0.8058	0.7905	24.7	N	None	0.17	0.037261	-0.343	0.1475	-0.8987	0.114207888934	0.895	0.907483	0.49	0.128392430309	0.132	0.480583637953	-3.18	0.179	0.418	0.128	None	None	1.20032E-06	6.33473E-05	0	0	0	None	0	0	1.20032E-06	0	0	0	None	N	None
33716	28	D/G	rs1300576084	0.2939	gnomAD-2.1.1	30	None	0.6399	0.4867	35.0	N	-0.092	-0.07	0.073027	-0.418	0.3133	-0.2986	0.270196249467	2.88	0.999997	0.482	0.409262747536	0.905	0.621486067772	-5.97	0.417	0.617	None	None	None	4.02E-06	0	0	0	0	None	0	None	4.02E-06	0	8.88E-06	0	None	N	None
33716	28	D/G	rs1300576084	0.2939	gnomAD-4.0.0	30	None	0.6399	0.4867	35.0	N	-0.092	-0.07	0.073027	-0.418	0.3133	-0.2986	0.270196249467	2.88	0.999997	0.482	0.409262747536	0.905	0.621486067772	-5.97	0.417	0.617	None	None	None	1.59115E-06	0	0	0	0	None	0	0	1.59115E-06	2.85794E-06	0	0	None	N	None
33716	28	D/N	None	0.2939	gnomAD-4.0.0	30	None	0.1574	0.1263	27.6	N	None	None	0.042736	-0.066	0.1584	-0.8807	0.0852562788459	2.085	0.999978	0.468	0.263140351381	0.078	0.656696677208	-4.17	0.252	0.277	None	None	None	1.5912E-06	0	2.28728E-05	0	0	None	0	0	1.5912E-06	0	0	0	None	N	None
33718	30	G/S	rs760711365	0.5136	gnomAD-2.1.1	32	None	0.7443	0.4645	31.0	N	-0.549	0.03	0.038943	-0.253	0.4962	0.0225	0.463496485926	2.59	1.0	0.363	0.356484672536	0.999	0.638076901436	-5.2	0.477	0.687	None	None	None	4.02E-06	0	0	0	0	None	0	None	4.02E-06	0	8.88E-06	0	None	N	None
33718	30	G/S	rs760711365	0.5136	gnomAD-4.0.0	32	None	0.7443	0.4645	31.0	N	-0.549	0.03	0.038943	-0.253	0.4962	0.0225	0.463496485926	2.59	1.0	0.363	0.356484672536	0.999	0.638076901436	-5.2	0.477	0.687	None	None	None	1.59119E-06	0	0	0	0	None	0	0	1.59119E-06	2.85794E-06	0	0	None	N	None
33719	31	S/C	rs2154136682	0.1596	gnomAD-4.0.0	33	None	0.1908	0.1507	33.0	N	None	0.25	0.031027	-0.51	0.3826	-0.2255	0.449725329957	1.185	0.999992	0.597	0.40032279838	1.0	0.601175487041	-4.3	0.547	0.739	0.003	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
33720	32	K/R	rs727503535	0.8490	gnomAD-2.1.1	34	None	0.0818	0.0734	29.3	N	0.229	0.36	0.014035	0.022	0.089	-0.9516	0.0694993386493	0.945	0.797617	0.491	0.295623431141	None	0.491271167994	-1.77	0.127	0.12	0.256	None	None	2.01E-05	0	1.45028E-04	0	0	None	0	None	2.01E-05	0	0	0	None	N	None
33720	32	K/R	rs727503535	0.8490	gnomAD-4.0.0	34	None	0.0818	0.0734	29.3	N	0.229	0.36	0.014035	0.022	0.089	-0.9516	0.0694993386493	0.945	0.797617	0.491	0.295623431141	None	0.491271167994	-1.77	0.127	0.12	0.256	None	None	9.54678E-06	0	1.37206E-04	0	0	None	0	0	9.54678E-06	0	0	0	None	N	None
33722	34	T/I	rs1372744849	0.4536	gnomAD-3.1.2	36	None	0.1462	0.2032	27.1	N	None	0.25	0.024411	-0.196	0.1516	-0.7852	0.0940497116312	0.82	0.7586	0.533	0.245660935333	0.017	0.679662942886	-3.58	0.175	0.151	0.276	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	N	None
33722	34	T/I	rs1372744849	0.4536	gnomAD-4.0.0	36	None	0.1462	0.2032	27.1	N	None	0.25	0.024411	-0.196	0.1516	-0.7852	0.0940497116312	0.82	0.7586	0.533	0.245660935333	0.017	0.679662942886	-3.58	0.175	0.151	0.276	None	None	2.56195E-06	1.69142E-05	0	0	0	None	0	0	2.56195E-06	0	0	2.84398E-05	None	N	None
33722	34	T/S	None	0.4536	gnomAD-4.0.0	36	None	0.1834	0.1978	26.5	N	None	0.31	0.032475	-0.948	0.1874	-0.6452	0.147252249548	0.18	0.752209	0.552	0.219573609325	0.646	0.610014379025	-3.02	0.302	0.459	0.03	None	None	3.18234E-06	0	4.57373E-05	0	0	None	0	0	3.18234E-06	0	0	0	None	N	None
33724	36	Y/C	None	0.1199	gnomAD-4.0.0	38	None	0.9503	0.9344	35.0	D	None	-1.74	0.10953	-2.042	0.8152	0.904	0.517873433737	4.0	0.999999	0.896	0.873223006722	1.0	0.793329536915	-7.8	0.873	0.839	None	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
33725	37	I/F	None	0.1622	gnomAD-4.0.0	39	None	0.4135	0.377	34.0	D	None	0.43	0.016689	-1.638	0.3014	-0.4423	0.533366148336	1.955	0.999999	0.466	0.629718971361	0.999	0.597833573818	-3.0	0.366	0.704	0.002	None	None	6.84188E-07	0	0	0	0	None	0	0	6.84188E-07	8.99441E-07	0	0	None	N	None
33725	37	I/T	rs1329737429	0.1622	gnomAD-2.1.1	39	None	0.4143	0.3453	28.0	N	-2.815	0.5	0.026842	-2.708	0.2184	-0.6732	0.334571908393	0.895	0.999911	0.421	0.618703310563	0.46	0.684315800667	-3.93	0.231	0.524	0.029	None	None	7.14E-06	0	0	0	0	None	0	None	7.14E-06	0	1.56E-05	0	None	N	None
33725	37	I/T	rs1329737429	0.1622	gnomAD-3.1.2	39	None	0.4143	0.3453	28.0	N	-2.815	0.5	0.026842	-2.708	0.2184	-0.6732	0.334571908393	0.895	0.999911	0.421	0.618703310563	0.46	0.684315800667	-3.93	0.231	0.524	0.029	None	None	1.31E-05	0	0	0	0	None	0	0	1.31E-05	2.94E-05	0	0	None	N	None
33725	37	I/T	rs1329737429	0.1622	gnomAD-4.0.0	39	None	0.4143	0.3453	28.0	N	-2.815	0.5	0.026842	-2.708	0.2184	-0.6732	0.334571908393	0.895	0.999911	0.421	0.618703310563	0.46	0.684315800667	-3.93	0.231	0.524	0.029	None	None	5.57685E-06	0	1.66667E-05	0	0	None	0	1.64366E-04	5.57685E-06	5.08544E-06	0	1.60108E-05	None	N	None
33725	37	I/V	rs878900245	0.1622	gnomAD-2.1.1	39	None	0.1062	0.1067	None	N	-1.741	None	None	-1.757	None	None	None	None	None	None	None	0.425	None	None	0.182	0.395	None	None	None	1.21E-05	0	2.9E-05	0	0	None	0	None	1.21E-05	0	1.77E-05	0	None	N	None
33725	37	I/V	rs878900245	0.1622	gnomAD-3.1.2	39	None	0.1062	0.1067	None	N	-1.741	None	None	-1.757	None	None	None	None	None	None	None	0.425	None	None	0.182	0.395	None	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
33725	37	I/V	rs878900245	0.1622	gnomAD-4.0.0	39	None	0.1062	0.1067	None	N	-1.741	None	None	-1.757	None	None	None	None	None	None	None	0.425	None	None	0.182	0.395	None	None	None	1.92088E-05	1.3344E-05	1.66672E-05	0	0	None	0	0	1.92088E-05	2.37319E-05	0	1.60092E-05	None	N	None
33726	38	V/A	None	0.0925	gnomAD-4.0.0	40	None	0.9083	0.8906	32.0	D	None	-0.34	0.032889	-2.524	0.4718	0.0615	0.136708418057	3.675	0.926707	0.684	0.680060995016	0.23	0.455123126507	-3.47	0.575	0.579	0.002	None	None	2.40064E-06	0	0	0	0	None	0	0	2.40064E-06	2.625E-06	0	0	None	N	None
33728	40	K/N	None	0.1701	gnomAD-4.0.0	42	None	0.9879	0.9829	28.9	N	None	0.38	0.027586	-1.866	0.3245	-0.5013	0.500868633848	2.87	0.996805	0.614	0.199424873507	1.0	0.726223230362	-4.03	0.438	0.822	0.018	None	None	1.59125E-06	0	0	0	0	None	0	0	1.59125E-06	0	1.43275E-05	0	None	N	None
33728	40	K/T	None	0.1701	gnomAD-4.0.0	42	None	0.9342	0.9051	35.0	N	None	0.43	0.039602	-1.71	0.3327	-0.3622	0.505338542393	1.975	0.999995	0.626	0.471456661759	1.0	0.720137059689	-4.9	0.521	0.817	0.02	None	None	1.59115E-06	0	0	0	0	None	0	0	1.59115E-06	2.85794E-06	0	0	None	N	None
33729	41	C/Y	None	0.0659	gnomAD-4.0.0	43	None	0.709	0.513	34.0	N	None	0.46	0.03987	-1.008	0.2903	-0.5396	0.5822824192	0.04	1.0	0.476	0.704489790954	0.999	0.7001709342	-7.37	0.403	0.707	0.181	None	None	1.59115E-06	0	0	0	0	None	0	0	1.59115E-06	2.85794E-06	0	0	None	N	None
33730	42	A/V	rs1690988435	0.1690	gnomAD-3.1.2	44	None	0.5018	0.3381	35.0	N	None	0.4	0.058544	-0.612	0.2032	-0.6318	0.393949661648	0.025	0.999988	0.467	0.377097596864	0.999	0.622467875481	-2.7	0.355	0.564	0.101	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	0	2.07383E-04	0	None	N	None
33730	42	A/V	rs1690988435	0.1690	gnomAD-4.0.0	44	None	0.5018	0.3381	35.0	N	None	0.4	0.058544	-0.612	0.2032	-0.6318	0.393949661648	0.025	0.999988	0.467	0.377097596864	0.999	0.622467875481	-2.7	0.355	0.564	0.101	None	None	2.56211E-06	0	0	0	0	None	0	0	2.56211E-06	0	2.68025E-05	0	None	N	None
33731	43	T/A	rs746383312	0.3685	gnomAD-2.1.1	50	None	0.1218	0.1023	29.3	N	-0.888	0.43	0.03804	-0.652	0.1436	-0.8003	0.210658340025	0.32	0.999841	0.49	0.162503812791	0.963	0.678396701813	-3.37	0.29	0.501	0.159	None	None	4.02E-06	0	0	0	0	None	0	None	4.02E-06	0	8.87E-06	0	None	N	None
33731	43	T/A	rs746383312	0.3685	gnomAD-4.0.0	50	None	0.1218	0.1023	29.3	N	-0.888	0.43	0.03804	-0.652	0.1436	-0.8003	0.210658340025	0.32	0.999841	0.49	0.162503812791	0.963	0.678396701813	-3.37	0.29	0.501	0.159	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
33732	44	T/A	rs1690986189	0.5092	gnomAD-4.0.0	54	None	0.1953	0.1236	25.7	N	None	0.4	0.01883	-0.245	0.1542	-0.8333	0.132915553808	0.335	0.999971	0.456	0.143124449307	0.499	0.597611904144	-3.52	0.213	0.475	0.438	None	None	2.40064E-06	0	0	0	0	None	0	0	2.40064E-06	2.625E-06	0	0	None	N	None
33732	44	T/I	rs1690985152	0.5092	gnomAD-3.1.2	54	None	0.7694	0.6008	35.0	N	None	0.36	0.018107	-0.304	0.3327	-0.4256	0.446917207442	1.05	0.999982	0.501	0.48418289745800003	0.998	0.703211188316	-4.62	0.389	0.575	0.13	None	None	6.57E-06	0	6.55E-05	0	0	None	0	0	6.57E-06	0	0	0	None	N	None
33732	44	T/I	rs1690985152	0.5092	gnomAD-4.0.0	54	None	0.7694	0.6008	35.0	N	None	0.36	0.018107	-0.304	0.3327	-0.4256	0.446917207442	1.05	0.999982	0.501	0.48418289745800003	0.998	0.703211188316	-4.62	0.389	0.575	0.13	None	None	2.56187E-06	1.69096E-05	1.69463E-05	0	0	None	0	0	2.56187E-06	0	0	0	None	N	None
33733	45	A/V	None	0.2924	gnomAD-4.0.0	60	None	0.5084	0.3301	32.0	N	None	0.39	0.047122	-0.255	0.1227	-0.8698	0.150069240935	0.71	0.986086	0.53	0.371344866733	0.883	0.626408696175	-2.55	0.205	0.387	0.088	None	None	3.18238E-06	0	0	0	0	None	1.88352E-05	0	3.18238E-06	2.85807E-06	0	0	None	N	None
33734	46	E/Q	None	0.7793	gnomAD-4.0.0	63	None	0.3951	0.2711	32.0	N	None	0.36	0.045701	0.092	0.1553	-0.8175	0.193047310743	1.1	0.999999	0.597	0.195762928549	0.922	0.664182603359	-2.02	0.233	0.501	0.07	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
33737	49	L/F	rs1690979679	0.3049	gnomAD-4.0.0	66	None	0.3828	0.285	24.9	N	None	0.39	0.017795	-0.924	0.0864	-1.0631	0.139999443684	1.15	0.591213	0.452	0.156986980423	0.37	0.487624883652	-2.64	0.145	0.51	0.037	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	I	None
33738	50	R/C	rs56273463	0.4597	gnomAD-2.1.1	67	None	0.733	0.6033	None	N	-0.495	None	None	-0.331	None	None	None	None	None	None	None	1.0	None	None	0.458	0.746	None	None	None	5.62195E-03	1.44664E-03	4.04457E-03	4.34783E-03	0	None	2.51617E-03	None	5.62195E-03	4.2E-03	8.65875E-03	8.56742E-03	None	N	None
33738	50	R/C	rs56273463	0.4597	gnomAD-3.1.2	67	None	0.733	0.6033	None	N	-0.495	None	None	-0.331	None	None	None	None	None	None	None	1.0	None	None	0.458	0.746	None	None	None	5.99495E-03	1.54515E-03	5.37001E-03	2.59366E-03	0	None	5.09626E-03	0	5.99495E-03	1.00106E-02	2.27932E-03	5.2531E-03	None	N	None
33738	50	R/C	rs56273463	0.4597	1000 genomes	67	None	0.733	0.6033	None	N	-0.495	None	None	-0.331	None	None	None	None	None	None	None	1.0	None	None	0.458	0.746	None	None	None	2.79553E-03	0	1.15E-02	None	0	5E-03	None	None	2.79553E-03	None	1E-03	None	None	N	None
33738	50	R/C	rs56273463	0.4597	gnomAD-4.0.0	67	None	0.733	0.6033	None	N	-0.495	None	None	-0.331	None	None	None	None	None	None	None	1.0	None	None	0.458	0.746	None	None	None	8.66767E-03	1.63969E-03	4.61574E-03	3.91865E-03	2.22826E-05	None	4.95746E-03	8.2481E-04	8.66767E-03	1.0505E-02	2.60211E-03	8.28986E-03	None	N	None
33738	50	R/H	rs192391568	0.4597	gnomAD-2.1.1	67	None	0.4966	0.4067	None	N	-1.225	None	None	-0.934	None	None	None	None	None	None	None	1.0	None	None	0.382	0.771	None	None	None	1.14138E-04	1.23987E-04	1.41427E-04	0	5.12E-05	None	5.55556E-04	None	1.14138E-04	0	3.9E-05	1.40252E-04	None	N	None
33738	50	R/H	rs192391568	0.4597	gnomAD-3.1.2	67	None	0.4966	0.4067	None	N	-1.225	None	None	-0.934	None	None	None	None	None	None	None	1.0	None	None	0.382	0.771	None	None	None	6.57E-05	1.20598E-04	1.3089E-04	0	0	None	0	0	6.57E-05	2.94E-05	2.07039E-04	0	None	N	None
33738	50	R/H	rs192391568	0.4597	1000 genomes	67	None	0.4966	0.4067	None	N	-1.225	None	None	-0.934	None	None	None	None	None	None	None	1.0	None	None	0.382	0.771	None	None	None	3.99361E-04	8E-04	1.4E-03	None	0	0	None	None	3.99361E-04	None	0	None	None	N	None
33738	50	R/H	rs192391568	0.4597	gnomAD-4.0.0	67	None	0.4966	0.4067	None	N	-1.225	None	None	-0.934	None	None	None	None	None	None	None	1.0	None	None	0.382	0.771	None	None	None	5.63842E-05	1.0659E-04	1.16624E-04	0	2.22806E-05	None	0	4.94886E-04	5.63842E-05	1.69515E-05	5.16007E-04	8.00179E-05	None	N	None
33738	50	R/S	None	0.4597	gnomAD-4.0.0	67	None	0.9595	0.93	35.0	N	None	0.48	0.021277	-0.511	0.2798	-0.5472	0.490879133311	-0.13	1.0	0.602	0.42526943336	1.0	0.584605753422	-5.13	0.411	0.75	0.032	None	None	6.84197E-07	2.98757E-05	0	0	0	None	0	0	6.84197E-07	0	0	0	None	N	None
33740	52	G/R	rs536705240	0.1486	gnomAD-2.1.1	69	None	0.9338	0.9259	33.0	N	-0.428	0.52	0.046667	-0.79	0.2839	-0.5465	0.460190044131	0.365	0.999317	0.537	0.661553648396	0.999	0.668207108974	-5.32	0.387	0.785	0.008	None	None	2.14E-05	2.47975E-04	0	0	0	None	0	None	2.14E-05	0	0	0	None	N	None
33740	52	G/R	rs536705240	0.1486	gnomAD-3.1.2	69	None	0.9338	0.9259	33.0	N	-0.428	0.52	0.046667	-0.79	0.2839	-0.5465	0.460190044131	0.365	0.999317	0.537	0.661553648396	0.999	0.668207108974	-5.32	0.387	0.785	0.008	None	None	5.91E-05	2.17129E-04	0	0	0	None	0	0	5.91E-05	0	0	0	None	N	None
33740	52	G/R	rs536705240	0.1486	gnomAD-4.0.0	69	None	0.9338	0.9259	33.0	N	-0.428	0.52	0.046667	-0.79	0.2839	-0.5465	0.460190044131	0.365	0.999317	0.537	0.661553648396	0.999	0.668207108974	-5.32	0.387	0.785	0.008	None	None	1.67297E-05	3.06487E-04	0	0	0	None	0	0	1.67297E-05	1.69515E-06	1.09794E-05	1.60041E-05	None	N	None
33741	53	Q/E	None	0.5015	gnomAD-4.0.0	70	None	0.2039	0.2184	27.9	N	None	0.49	0.058015	-0.103	0.1439	-0.7462	0.238205329635	-0.365	0.999179	0.496	0.152612264143	0.979	0.56356215477	-2.05	0.235	0.477	0.133	None	None	6.84185E-07	0	0	0	0	None	0	0	6.84185E-07	8.99429E-07	0	0	None	N	None
33741	53	Q/H	rs754625556	0.5015	gnomAD-2.1.1	70	None	0.4621	0.5568	26.6	N	-0.528	0.42	0.019095	-0.622	0.1582	-0.8516	0.414400824624	-0.13	0.970538	0.444	0.144782658237	0.999	0.599303841591	-3.33	0.237	0.611	0.014	None	None	4.02E-06	0	0	0	0	None	3.27E-05	None	4.02E-06	0	0	0	None	N	None
33741	53	Q/H	rs754625556	0.5015	gnomAD-4.0.0	70	None	0.4621	0.5568	26.6	N	-0.528	0.42	0.019095	-0.622	0.1582	-0.8516	0.414400824624	-0.13	0.970538	0.444	0.144782658237	0.999	0.599303841591	-3.33	0.237	0.611	0.014	None	None	1.5911E-06	0	0	0	0	None	0	0	1.5911E-06	0	1.43271E-05	0	None	N	None
33743	55	R/L	None	0.8244	gnomAD-4.0.0	83	None	0.3736	0.4611	34.0	N	None	0.31	0.072949	0.397	0.2296	-0.6439	0.299242708533	1.51	0.998997	0.568	0.483374165343	0.901	0.576000332832	-5.55	0.272	0.525	0.045	None	None	6.84183E-07	0	0	0	0	None	0	0	6.84183E-07	8.99425E-07	0	0	None	N	None
33743	55	R/Q	rs746547856	0.8244	gnomAD-2.1.1	83	None	0.1394	0.1462	34.0	N	0.259	0.28	0.060745	0.077	0.2674	-0.5395	0.404479960901	1.415	0.99335	0.529	0.17258766438	0.996	0.49491211772	-3.07	0.274	0.537	0.231	None	None	7.13E-06	8.27E-05	0	0	0	None	0	None	7.13E-06	0	0	0	None	N	None
33743	55	R/Q	rs746547856	0.8244	gnomAD-3.1.2	83	None	0.1394	0.1462	34.0	N	0.259	0.28	0.060745	0.077	0.2674	-0.5395	0.404479960901	1.415	0.99335	0.529	0.17258766438	0.996	0.49491211772	-3.07	0.274	0.537	0.231	None	None	1.31E-05	2.41E-05	0	0	1.92382E-04	None	0	0	1.31E-05	0	0	0	None	N	None
33743	55	R/Q	rs746547856	0.8244	gnomAD-4.0.0	83	None	0.1394	0.1462	34.0	N	0.259	0.28	0.060745	0.077	0.2674	-0.5395	0.404479960901	1.415	0.99335	0.529	0.17258766438	0.996	0.49491211772	-3.07	0.274	0.537	0.231	None	None	1.1154E-05	1.33486E-05	0	0	4.45474E-05	None	0	0	1.1154E-05	1.01708E-05	0	4.80292E-05	None	N	None
33745	57	T/R	None	0.2572	gnomAD-4.0.0	89	None	0.2222	0.3791	34.0	N	None	0.23	0.049949	-0.527	0.3047	-0.4684	0.472014145769	1.885	0.998596	0.733	0.591849201417	0.999	0.673516511917	-4.48	0.401	0.622	0.009	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
33746	58	R/C	rs199594729	0.4556	gnomAD-2.1.1	90	None	0.186	0.1691	33.0	N	-0.478	0.3	0.039157	-0.361	0.3114	-0.4509	0.46716595594	1.925	0.999971	0.657	0.667503297862	1.0	0.539735615253	-4.95	0.358	0.532	0.002	None	None	1.61E-05	0	0	0	0	None	6.54E-05	None	1.61E-05	0	1.77E-05	0	None	N	None
33746	58	R/C	rs199594729	0.4556	gnomAD-3.1.2	90	None	0.186	0.1691	33.0	N	-0.478	0.3	0.039157	-0.361	0.3114	-0.4509	0.46716595594	1.925	0.999971	0.657	0.667503297862	1.0	0.539735615253	-4.95	0.358	0.532	0.002	None	None	3.29E-05	0	1.96412E-04	0	0	None	0	0	3.29E-05	2.94E-05	0	0	None	N	None
33746	58	R/C	rs199594729	0.4556	gnomAD-4.0.0	90	None	0.186	0.1691	33.0	N	-0.478	0.3	0.039157	-0.361	0.3114	-0.4509	0.46716595594	1.925	0.999971	0.657	0.667503297862	1.0	0.539735615253	-4.95	0.358	0.532	0.002	None	None	9.91489E-06	2.67008E-05	5.00033E-05	0	4.45494E-05	None	0	0	9.91489E-06	4.23786E-06	1.09786E-05	4.80261E-05	None	N	None
33746	58	R/H	rs372584865	0.4556	gnomAD-2.1.1	90	None	0.1017	0.0844	None	N	-1.193	None	None	-0.997	None	None	None	None	None	None	None	0.067	None	None	0.203	0.345	None	None	None	1.61E-05	0	2.9E-05	0	0	None	3.27E-05	None	1.61E-05	0	1.77E-05	0	None	N	None
33746	58	R/H	rs372584865	0.4556	gnomAD-3.1.2	90	None	0.1017	0.0844	None	N	-1.193	None	None	-0.997	None	None	None	None	None	None	None	0.067	None	None	0.203	0.345	None	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
33746	58	R/H	rs372584865	0.4556	gnomAD-4.0.0	90	None	0.1017	0.0844	None	N	-1.193	None	None	-0.997	None	None	None	None	None	None	None	0.067	None	None	0.203	0.345	None	None	None	1.61112E-05	1.33522E-05	1.66672E-05	0	0	None	0	0	1.61112E-05	1.69512E-05	2.19553E-05	3.20184E-05	None	N	None
33746	58	R/P	rs372584865	0.4556	gnomAD-3.1.2	90	None	0.9482	0.9584	31.0	N	None	0.34	0.056987	0.211	0.2828	-0.5307	0.443734158058	1.435	0.999179	0.665	0.50466331119	0.994	0.485765010118	-4.17	0.331	0.555	0.016	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
33746	58	R/P	rs372584865	0.4556	gnomAD-4.0.0	90	None	0.9482	0.9584	31.0	N	None	0.34	0.056987	0.211	0.2828	-0.5307	0.443734158058	1.435	0.999179	0.665	0.50466331119	0.994	0.485765010118	-4.17	0.331	0.555	0.016	None	None	2.47865E-06	0	0	0	0	None	0	0	2.47865E-06	3.39024E-06	0	0	None	N	None
33747	59	Y/C	None	0.1857	gnomAD-4.0.0	91	None	0.3766	0.4381	35.0	N	None	0.21	0.03806	-1.224	0.3064	-0.439	0.47905792869	-0.075	0.99951	0.752	0.55025283692	1.0	0.813290715218	-6.1	0.447	0.672	0.144	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
33747	59	Y/H	rs1310463317	0.1857	gnomAD-2.1.1	91	None	0.6811	0.744	33.0	D	-1.088	0.21	0.029419	-1.063	0.3405	-0.3298	0.475177538353	0.8	0.989604	0.742	0.387529464389	0.998	0.814930796623	-3.43	0.466	0.505	0.042	None	None	4.02E-06	0	0	0	0	None	3.27E-05	None	4.02E-06	0	0	0	None	N	None
33747	59	Y/H	rs1310463317	0.1857	gnomAD-4.0.0	91	None	0.6811	0.744	33.0	D	-1.088	0.21	0.029419	-1.063	0.3405	-0.3298	0.475177538353	0.8	0.989604	0.742	0.387529464389	0.998	0.814930796623	-3.43	0.466	0.505	0.042	None	None	1.59108E-06	0	0	0	0	None	0	0	1.59108E-06	0	1.43271E-05	0	None	N	None
33748	60	T/I	rs750315507	0.3467	gnomAD-2.1.1	92	None	0.4984	0.4609	34.0	N	0.114	0.15	0.029855	-0.109	0.3865	-0.286	0.480749730577	1.845	1.0	0.547	0.545869088564	1.0	0.792247891426	-4.57	0.484	0.846	0.006	None	None	8.04E-06	0	0	0	0	None	0	None	8.04E-06	0	1.77E-05	0	None	N	None
33748	60	T/I	rs750315507	0.3467	gnomAD-4.0.0	92	None	0.4984	0.4609	34.0	N	0.114	0.15	0.029855	-0.109	0.3865	-0.286	0.480749730577	1.845	1.0	0.547	0.545869088564	1.0	0.792247891426	-4.57	0.484	0.846	0.006	None	None	1.36836E-06	0	0	0	0	None	0	0	1.36836E-06	1.79884E-06	0	0	None	N	None
33749	61	V/A	None	0.1213	gnomAD-4.0.0	93	None	0.7657	0.7856	33.0	N	None	0.08	0.029741	-1.74	0.35	-0.3148	0.461733961732	1.5	0.999969	0.686	0.773610404518	0.999	0.734827637672	-3.43	0.463	0.659	0.003	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
33749	61	V/G	None	0.1213	gnomAD-4.0.0	93	None	0.9573	0.968	34.0	D	None	0.05	0.048626	-2.343	0.5835	0.4714	0.521112319639	3.25	1.0	0.764	0.88705266108	1.0	0.625819683075	-5.87	0.692	0.843	None	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
33749	61	V/M	rs201554140	0.1213	gnomAD-2.1.1	93	None	0.7333	0.8111	None	N	-0.177	None	None	-0.199	None	None	None	None	None	None	None	1.0	None	None	0.416	0.721	None	None	None	7.92014E-04	7.89387E-03	2.54525E-04	0	0	None	3.27E-05	None	7.92014E-04	1.2001E-04	1.2486E-04	2.80505E-04	None	N	None
33749	61	V/M	rs201554140	0.1213	gnomAD-3.1.2	93	None	0.7333	0.8111	None	N	-0.177	None	None	-0.199	None	None	None	None	None	None	None	1.0	None	None	0.416	0.721	None	None	None	2.01748E-03	6.85394E-03	4.58295E-04	0	0	None	1.88466E-04	0	2.01748E-03	1.4699E-04	0	1.91205E-03	None	N	None
33749	61	V/M	rs201554140	0.1213	1000 genomes	93	None	0.7333	0.8111	None	N	-0.177	None	None	-0.199	None	None	None	None	None	None	None	1.0	None	None	0.416	0.721	None	None	None	1.39776E-03	5.3E-03	0	None	0	0	None	None	1.39776E-03	None	0	None	None	N	None
33749	61	V/M	rs201554140	0.1213	gnomAD-4.0.0	93	None	0.7333	0.8111	None	N	-0.177	None	None	-0.199	None	None	None	None	None	None	None	1.0	None	None	0.416	0.721	None	None	None	4.27539E-04	7.30394E-03	2.9993E-04	0	4.0107E-04	None	9.3794E-05	3.29924E-04	4.27539E-04	5.17016E-05	4.39155E-05	5.28101E-04	None	N	None
33750	62	I/F	rs1690954165	0.3104	gnomAD-4.0.0	94	None	0.3526	0.3042	None	N	None	None	None	-0.894	None	None	None	None	None	None	None	0.9	None	None	0.172	0.503	None	None	None	6.3642E-06	0	0	0	0	None	7.53296E-05	0	6.3642E-06	0	0	0	None	N	None
33750	62	I/T	None	0.3104	gnomAD-4.0.0	94	None	0.3358	0.2405	27.4	N	None	0.67	0.034786	-0.973	0.0761	-0.9575	0.187649354563	-0.945	0.998495	0.436	0.522717468363	0.659	0.635433673859	-1.9	0.346	0.489	1.0	None	None	1.36834E-06	0	0	0	0	None	0	0	1.36834E-06	1.79884E-06	0	0	None	N	None
33751	63	N/H	rs753658469	0.4822	gnomAD-2.1.1	96	None	0.2842	0.2865	None	N	-0.187	None	None	-0.353	None	None	None	None	None	None	None	0.999	None	None	0.522	0.668	None	None	None	2.85E-05	0	0	0	0	None	0	None	2.85E-05	0	6.24E-05	0	None	N	None
33751	63	N/H	rs753658469	0.4822	gnomAD-3.1.2	96	None	0.2842	0.2865	None	N	-0.187	None	None	-0.353	None	None	None	None	None	None	None	0.999	None	None	0.522	0.668	None	None	None	4.6E-05	0	0	0	0	None	0	0	4.6E-05	1.02878E-04	0	0	None	N	None
33751	63	N/H	rs753658469	0.4822	gnomAD-4.0.0	96	None	0.2842	0.2865	None	N	-0.187	None	None	-0.353	None	None	None	None	None	None	None	0.999	None	None	0.522	0.668	None	None	None	2.78835E-05	1.33444E-05	0	0	0	None	0	0	2.78835E-05	3.64448E-05	0	1.60087E-05	None	N	None
33751	63	N/S	rs1475672598	0.4822	gnomAD-2.1.1	96	None	0.0956	0.1226	33.0	N	0.154	0.11	0.019169	-0.174	0.3361	-0.3657	0.399918765951	1.375	0.999983	0.504	0.28798054836	0.98	0.6639149189	-2.97	0.288	0.533	0.213	None	None	3.18E-05	1.14758E-04	0	0	0	None	0	None	3.18E-05	0	0	0	None	N	None
33751	63	N/S	rs1475672598	0.4822	gnomAD-4.0.0	96	None	0.0956	0.1226	33.0	N	0.154	0.11	0.019169	-0.174	0.3361	-0.3657	0.399918765951	1.375	0.999983	0.504	0.28798054836	0.98	0.6639149189	-2.97	0.288	0.533	0.213	None	None	1.59107E-06	0	0	0	0	None	0	0	1.59107E-06	2.8578E-06	0	0	None	N	None
33753	65	F/C	None	0.6529	gnomAD-4.0.0	98	None	0.852	0.848	35.0	N	None	0.44	0.043328	-0.691	0.2455	-0.5822	0.55250470307	0.895	0.999998	0.578	0.680116873462	1.0	0.850476324558	-5.35	0.542	0.671	0.071	None	None	1.36835E-06	0	0	0	2.51902E-05	None	0	0	1.36835E-06	8.99428E-07	0	0	None	N	None
33753	65	F/S	rs764462637	0.6529	gnomAD-2.1.1	98	None	0.8395	0.848	35.0	N	-0.975	0.52	0.0526	-1.245	0.1821	-0.5979	0.614382434124	-0.565	0.999998	0.48	0.60538619643	1.0	0.836240530014	-4.77	0.53	0.657	0.251	None	None	2.41E-05	0	0	0	0	None	0	None	2.41E-05	0	5.32E-05	0	None	N	None
33753	65	F/S	rs764462637	0.6529	gnomAD-4.0.0	98	None	0.8395	0.848	35.0	N	-0.975	0.52	0.0526	-1.245	0.1821	-0.5979	0.614382434124	-0.565	0.999998	0.48	0.60538619643	1.0	0.836240530014	-4.77	0.53	0.657	0.251	None	None	9.57847E-06	0	0	0	0	None	0	0	9.57847E-06	1.07931E-05	0	3.31268E-05	None	N	None
33754	66	G/E	rs760939553	0.4894	gnomAD-2.1.1	99	None	0.9757	0.9595	34.0	N	-1.235	0.56	0.160812	-1.5	0.1236	-0.3388	0.526218639335	-2.32	1.0	0.616	0.293147016451	1.0	0.868802666664	-5.2	0.523	0.825	0.481	None	None	8.04E-06	0	0	0	1.11297E-04	None	0	None	8.04E-06	0	0	0	None	N	None
33754	66	G/E	rs760939553	0.4894	gnomAD-3.1.2	99	None	0.9757	0.9595	34.0	N	-1.235	0.56	0.160812	-1.5	0.1236	-0.3388	0.526218639335	-2.32	1.0	0.616	0.293147016451	1.0	0.868802666664	-5.2	0.523	0.825	0.481	None	None	6.57E-06	0	0	0	1.92456E-04	None	0	0	6.57E-06	0	0	0	None	N	None
33754	66	G/E	rs760939553	0.4894	gnomAD-4.0.0	99	None	0.9757	0.9595	34.0	N	-1.235	0.56	0.160812	-1.5	0.1236	-0.3388	0.526218639335	-2.32	1.0	0.616	0.293147016451	1.0	0.868802666664	-5.2	0.523	0.825	0.481	None	None	1.859E-06	0	0	0	6.68241E-05	None	0	0	1.859E-06	0	0	0	None	N	None
33755	67	K/E	None	1.1152	gnomAD-4.0.0	100	None	0.6494	0.6287	35.0	N	None	0.44	0.021714	0.211	0.2355	-0.5987	0.537137804364	-0.345	0.999749	0.597	0.268660756437	0.997	0.820131957531	-2.67	0.402	0.702	0.323	None	None	1.59111E-06	0	0	0	0	None	0	0	1.59111E-06	0	1.43275E-05	0	None	N	None
33757	69	S/N	rs1210718667	0.2347	gnomAD-2.1.1	103	None	0.1774	0.221	27.7	N	-0.362	0.48	0.020144	-0.824	0.1069	-0.9315	0.0978838310417	0.585	0.973608	0.491	0.18274738541	0.342	0.615984499454	-1.78	0.105	0.407	0.243	None	None	3.19E-05	0	0	0	0	None	0	None	3.19E-05	0	6.48E-05	0	None	N	None
33757	69	S/N	rs1210718667	0.2347	gnomAD-3.1.2	103	None	0.1774	0.221	27.7	N	-0.362	0.48	0.020144	-0.824	0.1069	-0.9315	0.0978838310417	0.585	0.973608	0.491	0.18274738541	0.342	0.615984499454	-1.78	0.105	0.407	0.243	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
33757	69	S/N	rs1210718667	0.2347	gnomAD-4.0.0	103	None	0.1774	0.221	27.7	N	-0.362	0.48	0.020144	-0.824	0.1069	-0.9315	0.0978838310417	0.585	0.973608	0.491	0.18274738541	0.342	0.615984499454	-1.78	0.105	0.407	0.243	None	None	6.57099E-06	0	0	0	0	None	0	0	6.57099E-06	1.46968E-05	0	0	None	N	None
33758	70	Y/H	None	0.2111	gnomAD-4.0.0	104	None	0.978	0.9852	34.0	D	None	-2.5	0.250353	-1.851	0.8936	1.0522	0.526113108519	4.435	0.99999	0.92	0.730513430788	1.0	0.83900642395	-4.33	0.894	0.848	None	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	0	0	3.66327E-05	None	N	None
33760	72	F/I	None	0.1225	gnomAD-4.0.0	106	None	0.9698	0.9769	35.0	N	None	0.28	0.026247	-1.126	0.4458	0.0092	0.544120415048	2.84	0.999996	0.682	0.594169782683	1.0	0.816102862358	-5.2	0.555	0.773	0.002	None	None	1.59109E-06	0	0	0	0	None	0	0	1.59109E-06	0	1.43275E-05	0	None	N	None
33760	72	F/L	None	0.1225	gnomAD-4.0.0	106	None	0.9975	0.9978	33.0	N	None	0.23	0.022818	-1.126	0.4552	-0.044	0.496083062219	2.735	1.0	0.65	0.696484460985	0.999	0.828175663948	-5.2	0.549	0.689	0.005	None	None	6.84183E-07	0	0	0	0	None	1.87413E-05	0	6.84183E-07	0	0	0	None	N	None
33761	73	R/Q	rs774790424	0.1472	gnomAD-2.1.1	107	None	0.7557	0.7709	32.0	N	-1.027	0.24	0.040095	-1.125	0.4144	-0.0756	0.496624975885	3.0	0.999928	0.762	0.376570364461	1.0	0.462715625763	-3.29	0.572	0.779	0.034	None	None	2.14E-05	0	0	0	0	None	0	None	2.14E-05	0	4.68E-05	0	None	N	None
33761	73	R/Q	rs774790424	0.1472	gnomAD-3.1.2	107	None	0.7557	0.7709	32.0	N	-1.027	0.24	0.040095	-1.125	0.4144	-0.0756	0.496624975885	3.0	0.999928	0.762	0.376570364461	1.0	0.462715625763	-3.29	0.572	0.779	0.034	None	None	1.97E-05	2.41E-05	0	0	0	None	0	0	1.97E-05	2.94E-05	0	0	None	N	None
33761	73	R/Q	rs774790424	0.1472	gnomAD-4.0.0	107	None	0.7557	0.7709	32.0	N	-1.027	0.24	0.040095	-1.125	0.4144	-0.0756	0.496624975885	3.0	0.999928	0.762	0.376570364461	1.0	0.462715625763	-3.29	0.572	0.779	0.034	None	None	1.23935E-05	1.33486E-05	0	0	2.22747E-05	None	0	0	1.23935E-05	1.52563E-05	0	0	None	N	None
33761	73	R/W	rs201421156	0.1472	gnomAD-2.1.1	107	None	0.9584	0.9606	None	D	-0.762	None	None	-0.585	None	None	None	None	None	None	None	1.0	None	None	0.655	0.801	None	None	None	9.27E-05	0	0	0	0	None	0	None	9.27E-05	0	2.02878E-04	0	None	N	None
33761	73	R/W	rs201421156	0.1472	gnomAD-3.1.2	107	None	0.9584	0.9606	None	D	-0.762	None	None	-0.585	None	None	None	None	None	None	None	1.0	None	None	0.655	0.801	None	None	None	1.70915E-04	2.41E-05	6.55E-05	0	0	None	0	0	1.70915E-04	3.52796E-04	0	0	None	N	None
33761	73	R/W	rs201421156	0.1472	gnomAD-4.0.0	107	None	0.9584	0.9606	None	D	-0.762	None	None	-0.585	None	None	None	None	None	None	None	1.0	None	None	0.655	0.801	None	None	None	1.92103E-04	1.33526E-05	1.66722E-05	0	0	None	0	0	1.92103E-04	2.54272E-04	1.09803E-05	1.12061E-04	None	N	None
33762	74	V/I	rs1385559568	0.0748	gnomAD-3.1.2	108	None	0.1216	0.1146	22.3	N	None	-0.51	0.024483	-0.822	0.2537	-0.6742	0.069198310528	1.23	0.993419	0.726	0.433047596574	0.003	0.377800256014	-0.58	0.151	0.203	0.194	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
33762	74	V/I	rs1385559568	0.0748	gnomAD-4.0.0	108	None	0.1216	0.1146	22.3	N	None	-0.51	0.024483	-0.822	0.2537	-0.6742	0.069198310528	1.23	0.993419	0.726	0.433047596574	0.003	0.377800256014	-0.58	0.151	0.203	0.194	None	None	2.47863E-06	0	0	0	0	None	0	0	2.47863E-06	3.39026E-06	0	0	None	N	None
33762	74	V/L	rs1385559568	0.0748	gnomAD-4.0.0	108	None	0.8	0.8123	22.5	N	None	-0.64	0.039408	-0.822	0.3219	-0.4967	0.0827083444963	2.34	0.998038	0.762	0.532359089423	0.001	0.492700815201	-2.32	0.311	0.321	0.01	None	None	1.36837E-06	0	0	0	0	None	0	0	1.36837E-06	1.79886E-06	0	0	None	N	None
33763	75	I/T	rs1180167121	0.0926	gnomAD-2.1.1	109	None	0.3476	0.4708	34.0	N	-2.965	0.48	0.030848	-2.885	0.2394	-0.6006	0.485913133983	0.82	0.999982	0.527	0.658352620329	0.992	0.765654683113	-3.47	0.459	0.753	0.324	None	None	4.02E-06	0	0	0	0	None	0	None	4.02E-06	0	8.87E-06	0	None	N	None
33763	75	I/T	rs1180167121	0.0926	gnomAD-4.0.0	109	None	0.3476	0.4708	34.0	N	-2.965	0.48	0.030848	-2.885	0.2394	-0.6006	0.485913133983	0.82	0.999982	0.527	0.658352620329	0.992	0.765654683113	-3.47	0.459	0.753	0.324	None	None	6.8418E-06	0	0	0	2.51902E-05	None	0	0	6.8418E-06	8.09485E-06	0	0	None	N	None
33764	76	A/D	None	0.0668	gnomAD-2.1.1	110	None	0.999	0.9994	35.0	D	-2.459	-1.3	0.119967	-2.897	0.8234	0.9268	0.550677112808	4.36	0.999998	0.815	0.815499709358	1.0	0.754997551441	-5.2	0.887	0.896	0.001	None	None	7.13E-06	4.13E-05	0	0	0	None	0	None	7.13E-06	0	7.8E-06	0	None	N	None
33764	76	A/D	None	0.0668	gnomAD-3.1.2	110	None	0.999	0.9994	35.0	D	-2.459	-1.3	0.119967	-2.897	0.8234	0.9268	0.550677112808	4.36	0.999998	0.815	0.815499709358	1.0	0.754997551441	-5.2	0.887	0.896	0.001	None	None	1.97E-05	4.83E-05	0	0	0	None	0	3.16456E-03	1.97E-05	0	0	0	None	N	None
33764	76	A/D	None	0.0668	gnomAD-4.0.0	110	None	0.999	0.9994	35.0	D	-2.459	-1.3	0.119967	-2.897	0.8234	0.9268	0.550677112808	4.36	0.999998	0.815	0.815499709358	1.0	0.754997551441	-5.2	0.887	0.896	0.001	None	None	1.97179E-05	4.82882E-05	0	0	0	None	0	3.16456E-03	1.97179E-05	0	0	0	None	N	None
33764	76	A/G	rs773542514	0.0668	gnomAD-2.1.1	110	None	0.6618	0.7333	34.0	D	-2.959	-1.23	0.044594	-2.39	0.5608	0.1129	0.0937571764374	3.075	0.999988	0.798	0.514755673002	0.291	0.652138352394	-3.47	0.717	0.371	0.043	None	None	1.21E-05	0	5.79E-05	0	0	None	0	None	1.21E-05	0	8.87E-06	0	None	N	None
33764	76	A/G	rs773542514	0.0668	gnomAD-3.1.2	110	None	0.6618	0.7333	34.0	D	-2.959	-1.23	0.044594	-2.39	0.5608	0.1129	0.0937571764374	3.075	0.999988	0.798	0.514755673002	0.291	0.652138352394	-3.47	0.717	0.371	0.043	None	None	1.31E-05	0	1.30924E-04	0	0	None	0	0	1.31E-05	0	0	0	None	N	None
33764	76	A/G	rs773542514	0.0668	gnomAD-4.0.0	110	None	0.6618	0.7333	34.0	D	-2.959	-1.23	0.044594	-2.39	0.5608	0.1129	0.0937571764374	3.075	0.999988	0.798	0.514755673002	0.291	0.652138352394	-3.47	0.717	0.371	0.043	None	None	9.91498E-06	0	8.33361E-05	0	0	None	1.56357E-05	1.64366E-04	9.91498E-06	5.08539E-06	1.09789E-05	3.20174E-05	None	N	None
33764	76	A/V	rs773542514	0.0668	gnomAD-2.1.1	110	None	0.9102	0.9477	35.0	D	-1.416	-1.25	0.0494	-1.128	0.7507	0.7322	0.42942473985	3.665	0.999991	0.776	0.707210613629	1.0	0.690095484257	-3.47	0.788	0.726	0.003	None	None	4.64E-05	4.13E-05	0	0	0	None	0	None	4.64E-05	0	9.36E-05	0	None	N	None
33764	76	A/V	rs773542514	0.0668	gnomAD-3.1.2	110	None	0.9102	0.9477	35.0	D	-1.416	-1.25	0.0494	-1.128	0.7507	0.7322	0.42942473985	3.665	0.999991	0.776	0.707210613629	1.0	0.690095484257	-3.47	0.788	0.726	0.003	None	None	6.57E-05	4.83E-05	0	0	0	None	0	0	6.57E-05	1.17588E-04	0	0	None	N	None
33764	76	A/V	rs773542514	0.0668	gnomAD-4.0.0	110	None	0.9102	0.9477	35.0	D	-1.416	-1.25	0.0494	-1.128	0.7507	0.7322	0.42942473985	3.665	0.999991	0.776	0.707210613629	1.0	0.690095484257	-3.47	0.788	0.726	0.003	None	None	9.85301E-05	4.00609E-05	0	0	0	None	0	0	9.85301E-05	1.2883E-04	0	6.40348E-05	None	N	None
33765	77	E/D	None	0.2934	gnomAD-4.0.0	111	None	0.8986	0.9403	27.7	N	None	0.4	0.016466	-1.473	0.3301	-0.4455	0.438787105072	1.965	0.967125	0.473	0.316198179892	0.994	0.71689927578	-2.3	0.295	0.459	0.015	None	None	2.40064E-06	0	0	0	0	None	0	0	2.40064E-06	2.625E-06	0	0	None	N	None
33768	80	F/S	None	0.3762	gnomAD-4.0.0	114	None	0.9615	0.9651	35.0	N	None	0.5	0.037689	-0.633	0.2408	-0.595	0.594131053256	0.44	0.999988	0.476	0.601658297244	1.0	0.719954073429	-6.48	0.515	0.665	0.082	None	None	2.40064E-06	0	0	0	0	None	0	0	2.40064E-06	2.625E-06	0	0	None	N	None
33769	81	G/A	rs1553499045	0.1801	gnomAD-3.1.2	115	None	0.9523	0.9515	33.0	D	None	-0.87	0.071609	-0.637	0.7242	0.677	0.480971576196	3.795	1.0	0.854	0.558031983626	0.999	0.696886777878	-5.2	0.84	0.773	0.098	None	None	6.57E-06	0	6.55E-05	0	0	None	0	0	6.57E-06	0	0	0	None	N	None
33769	81	G/A	rs1553499045	0.1801	gnomAD-4.0.0	115	None	0.9523	0.9515	33.0	D	None	-0.87	0.071609	-0.637	0.7242	0.677	0.480971576196	3.795	1.0	0.854	0.558031983626	0.999	0.696886777878	-5.2	0.84	0.773	0.098	None	None	6.57315E-06	0	6.54536E-05	0	0	None	0	0	6.57315E-06	0	0	0	None	N	None
33769	81	G/C	rs1690932780	0.1801	gnomAD-3.1.2	115	None	0.9851	0.9851	35.0	D	None	-0.9	0.176384	-0.897	0.7643	0.8259	0.478569009243	4.345	1.0	0.845	0.875651832405	1.0	0.728684782982	-7.8	0.84	0.887	0.002	None	None	6.57E-06	0	6.55E-05	0	0	None	0	0	6.57E-06	0	0	0	None	N	None
33769	81	G/C	rs1690932780	0.1801	gnomAD-4.0.0	115	None	0.9851	0.9851	35.0	D	None	-0.9	0.176384	-0.897	0.7643	0.8259	0.478569009243	4.345	1.0	0.845	0.875651832405	1.0	0.728684782982	-7.8	0.84	0.887	0.002	None	None	6.57246E-06	0	6.54622E-05	0	0	None	0	0	6.57246E-06	0	0	0	None	N	None
33769	81	G/S	rs1690932780	0.1801	gnomAD-4.0.0	115	None	0.9348	0.9363	34.0	D	None	-0.84	0.089097	-0.943	0.7242	0.677	0.463496485926	3.54	1.0	0.781	0.55342899667	1.0	0.691917657852	-5.2	0.838	0.873	0.009	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
33771	83	S/C	None	0.0837	gnomAD-4.0.0	118	None	0.8601	0.8557	35.0	D	None	-0.29	0.152208	-0.611	0.6508	0.6316	0.458380669649	4.18	0.999999	0.545	0.677953048899	1.0	0.587771654129	-4.27	0.664	0.849	0.009	None	None	2.73672E-06	0	0	0	0	None	0	0	2.73672E-06	3.59772E-06	0	0	None	N	None
33771	83	S/R	None	0.0837	gnomAD-4.0.0	118	None	0.9987	0.9991	32.0	D	None	-0.25	0.061579	-0.93	0.5604	0.2495	0.490635962763	3.835	0.999123	0.499	0.50857664894	1.0	0.633182644844	-4.23	0.634	0.859	0.009	None	None	7.20193E-06	6.33473E-05	0	0	0	None	0	0	7.20193E-06	6.56251E-06	0	0	None	N	None
33772	84	K/E	rs1362410602	0.8842	gnomAD-3.1.2	119	None	0.1555	0.146	31.0	N	None	0.49	0.012665	-0.011	0.0617	-1.0289	0.12516921493	-1.125	0.900133	0.509	0.193865811164	0.028	0.469683289528	-1.5	0.151	0.409	0.627	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
33772	84	K/E	rs1362410602	0.8842	gnomAD-4.0.0	119	None	0.1555	0.146	31.0	N	None	0.49	0.012665	-0.011	0.0617	-1.0289	0.12516921493	-1.125	0.900133	0.509	0.193865811164	0.028	0.469683289528	-1.5	0.151	0.409	0.627	None	None	2.56176E-06	0	0	0	0	None	0	0	2.56176E-06	2.39262E-06	1.33994E-05	0	None	N	None
33772	84	K/N	rs1255240121	0.8842	gnomAD-4.0.0	119	None	0.3247	0.3564	25.2	N	None	0.39	0.024138	0.182	0.1115	-0.8867	0.118706545267	1.08	0.945643	0.565	0.156986980423	0.315	0.487193197012	-2.53	0.107	0.459	0.193	None	None	3.18225E-06	0	0	0	5.54508E-05	None	0	0	3.18225E-06	0	0	0	None	N	None
33773	85	P/S	rs768248494	0.3441	gnomAD-2.1.1	120	None	0.6618	0.6903	32.0	N	-1.002	0.03	0.036658	-1.393	0.3489	-0.2481	0.29034342778	2.775	0.999994	0.353	0.313818047136	0.979	0.612533569336	-6.27	0.38	0.714	0.004	None	None	4.02E-06	0	0	0	0	None	0	None	4.02E-06	0	8.86E-06	0	None	N	None
33773	85	P/S	rs768248494	0.3441	gnomAD-4.0.0	120	None	0.6618	0.6903	32.0	N	-1.002	0.03	0.036658	-1.393	0.3489	-0.2481	0.29034342778	2.775	0.999994	0.353	0.313818047136	0.979	0.612533569336	-6.27	0.38	0.714	0.004	None	None	1.59118E-06	0	0	0	0	None	0	0	1.59118E-06	2.85788E-06	0	0	None	N	None
33775	87	E/G	None	0.8080	gnomAD-4.0.0	122	None	0.2132	0.2518	34.0	D	None	0.09	0.040744	-0.314	0.2033	-0.6952	0.13317876906	1.34	0.999198	0.223	0.414670632993	0.379	0.578851997852	-4.78	0.207	0.598	0.005	None	None	1.59109E-06	0	0	0	0	None	0	0	1.59109E-06	2.85786E-06	0	0	None	N	None
33776	88	P/A	rs746665837	0.3448	gnomAD-2.1.1	123	None	0.0806	0.0814	34.0	N	-1.556	0.23	0.038299	-1.372	0.3333	-0.4339	0.441890510504	1.46	0.999998	0.194	0.305730143919	0.998	0.617019176483	-5.01	0.295	0.811	0.368	None	None	8.03E-06	0	0	0	0	None	0	None	8.03E-06	0	1.77E-05	0	None	N	None
33776	88	P/A	rs746665837	0.3448	gnomAD-3.1.2	123	None	0.0806	0.0814	34.0	N	-1.556	0.23	0.038299	-1.372	0.3333	-0.4339	0.441890510504	1.46	0.999998	0.194	0.305730143919	0.998	0.617019176483	-5.01	0.295	0.811	0.368	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
33776	88	P/A	rs746665837	0.3448	gnomAD-4.0.0	123	None	0.0806	0.0814	34.0	N	-1.556	0.23	0.038299	-1.372	0.3333	-0.4339	0.441890510504	1.46	0.999998	0.194	0.305730143919	0.998	0.617019176483	-5.01	0.295	0.811	0.368	None	None	5.57713E-06	0	0	0	0	None	0	0	5.57713E-06	6.78048E-06	0	1.60092E-05	None	N	None
33776	88	P/L	rs536357517	0.3448	gnomAD-2.1.1	123	None	0.1984	0.2155	35.0	N	-0.603	0.22	0.046719	-0.725	0.3708	-0.3483	0.468442230762	1.71	1.0	0.189	0.677900743141	1.0	0.675119638443	-6.35	0.335	0.83	0.373	None	None	8.03E-06	1.29182E-04	0	0	0	None	0	None	8.03E-06	0	0	0	None	N	None
33776	88	P/L	rs536357517	0.3448	gnomAD-3.1.2	123	None	0.1984	0.2155	35.0	N	-0.603	0.22	0.046719	-0.725	0.3708	-0.3483	0.468442230762	1.71	1.0	0.189	0.677900743141	1.0	0.675119638443	-6.35	0.335	0.83	0.373	None	None	2.63E-05	9.65E-05	0	0	0	None	0	0	2.63E-05	0	0	0	None	N	None
33776	88	P/L	rs536357517	0.3448	1000 genomes	123	None	0.1984	0.2155	35.0	N	-0.603	0.22	0.046719	-0.725	0.3708	-0.3483	0.468442230762	1.71	1.0	0.189	0.677900743141	1.0	0.675119638443	-6.35	0.335	0.83	0.373	None	None	1.99681E-04	8E-04	0	None	0	0	None	None	1.99681E-04	None	0	None	None	N	None
33776	88	P/L	rs536357517	0.3448	gnomAD-4.0.0	123	None	0.1984	0.2155	35.0	N	-0.603	0.22	0.046719	-0.725	0.3708	-0.3483	0.468442230762	1.71	1.0	0.189	0.677900743141	1.0	0.675119638443	-6.35	0.335	0.83	0.373	None	None	3.71775E-06	7.99595E-05	0	0	0	None	0	0	3.71775E-06	0	0	0	None	N	None
33777	89	S/L	rs983842520	0.1445	gnomAD-3.1.2	124	None	0.5114	0.5459	35.0	N	None	0.22	0.10696	0.05	0.3374	-0.2642	0.24825362791	2.4	0.999292	0.251	0.596065454935	0.948	0.523676931858	-4.01	0.378	0.678	0.059	None	None	1.31E-05	0	6.55E-05	0	0	None	0	0	1.31E-05	0	0	4.77555E-04	None	N	None
33777	89	S/L	rs983842520	0.1445	gnomAD-4.0.0	124	None	0.5114	0.5459	35.0	N	None	0.22	0.10696	0.05	0.3374	-0.2642	0.24825362791	2.4	0.999292	0.251	0.596065454935	0.948	0.523676931858	-4.01	0.378	0.678	0.059	None	None	4.05978E-06	0	6.15536E-05	0	0	None	0	0	4.05978E-06	2.40981E-06	0	3.40229E-05	None	N	None
33778	90	E/K	None	0.6441	gnomAD-4.0.0	125	None	0.1634	0.178	26.3	N	None	0.21	0.050123	0.421	0.1897	-0.786	0.108382069143	1.22	0.999814	0.371	0.325263233342	0.345	0.621982336044	-2.43	0.209	0.558	0.172	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
33779	91	P/S	rs1690922403	0.3238	gnomAD-3.1.2	126	None	0.1951	0.2584	29.1	N	None	0.23	0.051272	-0.54	0.2483	-0.5922	0.211833744035	1.315	0.999996	0.189	0.239901079897	0.997	0.600049257278	-5.51	0.295	0.79	0.071	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
33779	91	P/S	rs1690922403	0.3238	gnomAD-4.0.0	126	None	0.1951	0.2584	29.1	N	None	0.23	0.051272	-0.54	0.2483	-0.5922	0.211833744035	1.315	0.999996	0.189	0.239901079897	0.997	0.600049257278	-5.51	0.295	0.79	0.071	None	None	3.84316E-06	0	0	0	0	None	0	0	3.84316E-06	7.17796E-06	0	0	None	N	None
33780	92	T/I	rs2154136558	0.2066	gnomAD-4.0.0	127	None	0.1054	0.1094	27.3	N	None	0.16	0.00708	None	0.0557	-1.0249	0.0903394030496	-1.69	0.692796	0.215	0.239901079897	None	0.461632370949	-2.1	0.195	0.355	0.218	None	None	1.36835E-06	0	0	0	0	None	0	0	1.36835E-06	0	2.31863E-05	0	None	N	None
33781	93	I/V	rs1029128193	0.3439	gnomAD-4.0.0	128	None	0.057	0.0564	21.7	N	None	0.29	0.00976	-0.521	0.0984	-1.0085	0.0703051542146	-0.135	0.999931	0.19	0.141422826196	None	0.305267453194	0.17	0.137	0.074	0.642	None	None	4.77324E-06	0	0	0	0	None	0	0	4.77324E-06	8.57334E-06	0	0	None	N	None
33782	94	T/I	rs771566432	0.2137	gnomAD-2.1.1	130	None	0.8705	0.8515	None	N	-0.253	None	None	-0.326	None	None	None	None	None	None	None	1.0	None	None	0.377	0.786	None	None	None	3.18E-05	1.14811E-04	0	0	0	None	0	None	3.18E-05	0	0	0	None	N	None
33782	94	T/I	rs771566432	0.2137	gnomAD-3.1.2	130	None	0.8705	0.8515	None	N	-0.253	None	None	-0.326	None	None	None	None	None	None	None	1.0	None	None	0.377	0.786	None	None	None	1.97E-05	7.25E-05	0	0	0	None	0	0	1.97E-05	0	0	0	None	N	None
33782	94	T/I	rs771566432	0.2137	gnomAD-4.0.0	130	None	0.8705	0.8515	None	N	-0.253	None	None	-0.326	None	None	None	None	None	None	None	1.0	None	None	0.377	0.786	None	None	None	4.33779E-06	9.34854E-05	0	0	0	None	0	0	4.33779E-06	0	0	0	None	N	None
33782	94	T/S	rs771566432	0.2137	gnomAD-4.0.0	130	None	0.6498	0.6269	34.0	N	-1.606	0.2	0.029171	-1.447	0.2706	-0.516	0.421723341277	1.92	0.999998	0.201	0.219573609325	0.976	0.632744550705	-3.25	0.204	0.573	0.033	None	None	6.84174E-07	0	0	0	2.51902E-05	None	0	0	6.84174E-07	0	0	0	None	N	None
33783	95	K/R	None	0.7392	gnomAD-4.0.0	131	None	0.0958	0.0983	35.0	N	None	0.2	0.013163	-0.084	0.2414	-0.5605	0.377492468063	1.08	0.999973	0.306	0.303123707472	0.972	0.536455214024	-2.11	0.211	0.621	0.067	None	None	1.59107E-06	0	0	0	0	None	0	0	1.59107E-06	2.85785E-06	0	0	None	N	None
33784	96	E/Q	rs918368881	0.3299	gnomAD-2.1.1	132	None	0.6249	0.5785	33.0	N	0.412	0.16	0.033824	0.224	0.2687	-0.5168	0.440112360415	1.43	0.999999	0.174	0.292062946507	0.996	0.60610127449	-2.29	0.25	0.602	0.012	None	None	3.18E-05	0	1.17924E-03	0	0	None	0	None	3.18E-05	0	0	0	None	N	None
33784	96	E/Q	rs918368881	0.3299	gnomAD-3.1.2	132	None	0.6249	0.5785	33.0	N	0.412	0.16	0.033824	0.224	0.2687	-0.5168	0.440112360415	1.43	0.999999	0.174	0.292062946507	0.996	0.60610127449	-2.29	0.25	0.602	0.012	None	None	1.31E-05	0	1.31027E-04	0	0	None	0	0	1.31E-05	0	0	0	None	N	None
33784	96	E/Q	rs918368881	0.3299	gnomAD-4.0.0	132	None	0.6249	0.5785	33.0	N	0.412	0.16	0.033824	0.224	0.2687	-0.5168	0.440112360415	1.43	0.999999	0.174	0.292062946507	0.996	0.60610127449	-2.29	0.25	0.602	0.012	None	None	1.31453E-05	0	1.31027E-04	0	0	None	0	0	1.31453E-05	0	0	0	None	N	None

Whole Population MAF	African (AFR)	Latin American (AMR)
Amish (AMS)	Ashkenazi Jewish (ASJ)	East Asian (EAS)
European/1KGP (EUR)	Finnish (FIN)	Middle Eastern (MDE)
Non-Finnish European (NFE)	South Asian (SAS)	Other (OTH)

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											10										20										30										40										50										60										70										80										90
A	D	V	P	D	P	P	R	G	V	K	V	S	D	V	S	R	D	S	V	N	L	T	W	T	E	P	A	S	D	G	G	S	K	I	T	N	Y	I	V	E	K	C	A	T	T	A	E	R	W	L	R	V	G	Q	A	R	E	T	R	Y	T	V	I	N	L	F	G	K	T	S	Y	Q	F	R	V	I	A	E	N	K	F	G	L	S	K	P	S	E	P	S	E	P	T	I	T	K	E	D	K	T	R	A	M	N	Y	D	E	E	V	D	E	T	R	E	V	S	M	T	K	A	S	H	S	S	T	K	E	L	Y	E	K	Y	M	I	A	E	D	L	G	R	G	E	F	G	I	V	H	R	C	V	E	T	S	S	K	K	T	Y	M	A	K	F	V	K	V	K	G	T	D	Q	V	L	V	K	K	E	I	S	I	L	N	I	A	R	H	R	N	I	L	H	L	H	E	S	F	E	S	M	E	E	L	V	M	I	F	E	F	I	S	G	L	D	I	F	E	R	I	N	T	S	A	F	E	L	N	E	R	E	I	V	S	Y	V	H	Q	V	C	E	A	L	Q	F	L	H	S	H	N	I	G	H	F	D	I	R	P	E	N	I	I	Y	Q	T	R	R	S	S	T	I	K	I	I	E	F	G	Q	A	R	Q	L	K	P	G	D	N	F	R	L	L	F	T	A	P	E	Y	Y	A	P	E	V	H	Q	H	D	V	V	S	T	A	T	D	M	W	S	L	G	T	L	V	Y	V	L	L	S	G	I	N	P	F	L	A	E	T	N	Q	Q	I	I	E	N	I	M	N	A	E	Y	T	F	D	E	E	A	F	K	E	I	S	I	E	A	M	D	F	V	D	R	L	L	V	K	E	R	K	S	R	M	T	A	S	E	A	L	Q	H	P	W	L	K	Q	K	I	E	R	V	S	T	K	V	I	R	T	L	K	H	R	R	Y	Y	H	T	L	I	K	K	D	L	N	M	V	V	S	A	A	R	I	S	C	G	G	A	I	R	S	Q	K	G	V	S	V	A	K	V	K	V	A	S	I	E	I	G	P	V	S	G	Q	I	M	H	A	V	G	E	E	G	G	H	V	K	Y	V	C	K	I	E	N	Y	D	Q	S	T	Q	V	T	W	Y	F	G	V	R	Q	L	E	N	S	E	K	Y	E	I	T	Y	E	D	G	V	A	I	L	Y	V	K	D	I	T	K	L	D	D	G	T	Y	R	C	K	V	V	N	D	Y	G	E	D	S	S	Y	A	E	L	F	V	K	G	V	R	E	V	Y	D	Y
-	-	V	P	D	P	P	R	G	V	K	V	S	D	V	S	R	D	S	V	N	L	T	W	T	E	P	A	S	D	G	G	S	K	I	T	N	Y	I	V	E	K	C	A	T	T	A	E	R	W	L	R	V	G	Q	A	R	E	T	R	Y	T	V	I	N	L	F	G	K	T	S	Y	Q	F	R	V	I	A	E	N	K	F	G	L	S	K	P	S	E	P	S	E	P	T	I	T	K	E	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-

											10										20										30										40										50										60										70										80										90
A	D	V	P	D	P	P	R	G	V	K	V	S	D	V	S	R	D	S	V	N	L	T	W	T	E	P	A	S	D	G	G	S	K	I	T	N	Y	I	V	E	K	C	A	T	T	A	E	R	W	L	R	V	G	Q	A	R	E	T	R	Y	T	V	I	N	L	F	G	K	T	S	Y	Q	F	R	V	I	A	E	N	K	F	G	L	S	K	P	S	E	P	S	E	P	T	I	T	K	E	D	K	T	R	A	M	N	Y	D	E	E	V	D	E	T	R	E	V	S	M	T	K	A	S	H	S	S	T	K	E	L	Y	E	K	Y	M	I	A	E	D	L	G	R	G	E	F	G	I	V	H	R	C	V	E	T	S	S	K	K	T	Y	M	A	K	F	V	K	V	K	G	T	D	Q	V	L	V	K	K	E	I	S	I	L	N	I	A	R	H	R	N	I	L	H	L	H	E	S	F	E	S	M	E	E	L	V	M	I	F	E	F	I	S	G	L	D	I	F	E	R	I	N	T	S	A	F	E	L	N	E	R	E	I	V	S	Y	V	H	Q	V	C	E	A	L	Q	F	L	H	S	H	N	I	G	H	F	D	I	R	P	E	N	I	I	Y	Q	T	R	R	S	S	T	I	K	I	I	E	F	G	Q	A	R	Q	L	K	P	G	D	N	F	R	L	L	F	T	A	P	E	Y	Y	A	P	E	V	H	Q	H	D	V	V	S	T	A	T	D	M	W	S	L	G	T	L	V	Y	V	L	L	S	G	I	N	P	F	L	A	E	T	N	Q	Q	I	I	E	N	I	M	N	A	E	Y	T	F	D	E	E	A	F	K	E	I	S	I	E	A	M	D	F	V	D	R	L	L	V	K	E	R	K	S	R	M	T	A	S	E	A	L	Q	H	P	W	L	K	Q	K	I	E	R	V	S	T	K	V	I	R	T	L	K	H	R	R	Y	Y	H	T	L	I	K	K	D	L	N	M	V	V	S	A	A	R	I	S	C	G	G	A	I	R	S	Q	K	G	V	S	V	A	K	V	K	V	A	S	I	E	I	G	P	V	S	G	Q	I	M	H	A	V	G	E	E	G	G	H	V	K	Y	V	C	K	I	E	N	Y	D	Q	S	T	Q	V	T	W	Y	F	G	V	R	Q	L	E	N	S	E	K	Y	E	I	T	Y	E	D	G	V	A	I	L	Y	V	K	D	I	T	K	L	D	D	G	T	Y	R	C	K	V	V	N	D	Y	G	E	D	S	S	Y	A	E	L	F	V	K	G	V	R	E	V	Y	D	Y
-	-	V	P	D	P	P	R	G	V	K	V	S	D	V	S	R	D	S	V	N	L	T	W	T	E	P	A	S	D	G	G	S	K	I	T	N	Y	I	V	E	K	C	A	T	T	A	E	R	W	L	R	V	G	Q	A	R	E	T	R	Y	T	V	I	N	L	F	G	K	T	S	Y	Q	F	R	V	I	A	E	N	K	F	G	L	S	K	P	S	E	P	S	E	P	T	I	T	K	E	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-

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											10										20										30										40										50										60										70										80										90
A	D	V	P	D	P	P	R	G	V	K	V	S	D	V	S	R	D	S	V	N	L	T	W	T	E	P	A	S	D	G	G	S	K	I	T	N	Y	I	V	E	K	C	A	T	T	A	E	R	W	L	R	V	G	Q	A	R	E	T	R	Y	T	V	I	N	L	F	G	K	T	S	Y	Q	F	R	V	I	A	E	N	K	F	G	L	S	K	P	S	E	P	S	E	P	T	I	T	K	E	D	K	T	R	A	M	N	Y	D	E	E	V	D	E	T	R	E	V	S	M	T	K	A	S	H	S	S	T	K	E	L	Y	E	K	Y	M	I	A	E	D	L	G	R	G	E	F	G	I	V	H	R	C	V	E	T	S	S	K	K	T	Y	M	A	K	F	V	K	V	K	G	T	D	Q	V	L	V	K	K	E	I	S	I	L	N	I	A	R	H	R	N	I	L	H	L	H	E	S	F	E	S	M	E	E	L	V	M	I	F	E	F	I	S	G	L	D	I	F	E	R	I	N	T	S	A	F	E	L	N	E	R	E	I	V	S	Y	V	H	Q	V	C	E	A	L	Q	F	L	H	S	H	N	I	G	H	F	D	I	R	P	E	N	I	I	Y	Q	T	R	R	S	S	T	I	K	I	I	E	F	G	Q	A	R	Q	L	K	P	G	D	N	F	R	L	L	F	T	A	P	E	Y	Y	A	P	E	V	H	Q	H	D	V	V	S	T	A	T	D	M	W	S	L	G	T	L	V	Y	V	L	L	S	G	I	N	P	F	L	A	E	T	N	Q	Q	I	I	E	N	I	M	N	A	E	Y	T	F	D	E	E	A	F	K	E	I	S	I	E	A	M	D	F	V	D	R	L	L	V	K	E	R	K	S	R	M	T	A	S	E	A	L	Q	H	P	W	L	K	Q	K	I	E	R	V	S	T	K	V	I	R	T	L	K	H	R	R	Y	Y	H	T	L	I	K	K	D	L	N	M	V	V	S	A	A	R	I	S	C	G	G	A	I	R	S	Q	K	G	V	S	V	A	K	V	K	V	A	S	I	E	I	G	P	V	S	G	Q	I	M	H	A	V	G	E	E	G	G	H	V	K	Y	V	C	K	I	E	N	Y	D	Q	S	T	Q	V	T	W	Y	F	G	V	R	Q	L	E	N	S	E	K	Y	E	I	T	Y	E	D	G	V	A	I	L	Y	V	K	D	I	T	K	L	D	D	G	T	Y	R	C	K	V	V	N	D	Y	G	E	D	S	S	Y	A	E	L	F	V	K	G	V	R	E	V	Y	D	Y
-	-	V	P	D	P	P	R	G	V	K	V	S	D	V	S	R	D	S	V	N	L	T	W	T	E	P	A	S	D	G	G	S	K	I	T	N	Y	I	V	E	K	C	A	T	T	A	E	R	W	L	R	V	G	Q	A	R	E	T	R	Y	T	V	I	N	L	F	G	K	T	S	Y	Q	F	R	V	I	A	E	N	K	F	G	L	S	K	P	S	E	P	S	E	P	T	I	T	K	E	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-