TITINdb

Map SAVs to Structure

Position	Domain position	SAV	Structural Position	RS	Q(SASA)	Disease	Source	MAF
6	1	P/L	1	rs201490999	0.1070	None	gnomAD-2.1.1	1.2E-05
6	1	P/L	1	rs201490999	0.1070	None	gnomAD-3.1.2	1.31E-05
6	1	P/L	1	rs201490999	0.1070	None	gnomAD-4.0.0	3.53224E-05
7	2	T/A	2	rs752073551	0.2046	None	gnomAD-2.1.1	7.97E-06
7	2	T/A	2	rs752073551	0.2046	None	gnomAD-4.0.0	1.59103E-06
7	2	T/K	2	rs761344572	0.2046	None	gnomAD-2.1.1	3.98E-06
7	2	T/K	2	rs761344572	0.2046	None	gnomAD-4.0.0	1.36833E-06
7	2	T/M	2	rs761344572	0.2046	None	gnomAD-2.1.1	1.2E-05
7	2	T/M	2	rs761344572	0.2046	None	gnomAD-4.0.0	1.29992E-05
7	2	T/R	2	None	0.2046	None	gnomAD-4.0.0	6.84166E-07
8	3	F/I	3	None	0.1222	None	gnomAD-4.0.0	1.20032E-06
9	4	T/K	4	rs146123323	0.4320	None	gnomAD-3.1.2	6.57E-06
9	4	T/K	4	rs146123323	0.4320	None	gnomAD-4.0.0	6.57134E-06
9	4	T/M	4	rs146123323	0.4320	None	gnomAD-2.1.1	3.19E-05
9	4	T/M	4	rs146123323	0.4320	None	gnomAD-3.1.2	2.63E-05
9	4	T/M	4	rs146123323	0.4320	None	gnomAD-4.0.0	1.05341E-05
9	4	T/S	4	rs1298028827	0.4320	None	gnomAD-2.1.1	7.97E-06
9	4	T/S	4	rs1298028827	0.4320	None	gnomAD-4.0.0	2.73662E-06
10	5	Q/H	5	None	0.2155	None	gnomAD-4.0.0	1.59093E-06
10	5	Q/R	5	None	0.2155	None	gnomAD-4.0.0	1.59096E-06
11	6	P/A	7	None	0.1582	None	gnomAD-4.0.0	1.36829E-06
11	6	P/L	7	rs768624416	0.1582	None	gnomAD-2.1.1	7.97E-06
11	6	P/L	7	rs768624416	0.1582	None	gnomAD-3.1.2	3.29E-05
11	6	P/L	7	rs768624416	0.1582	None	gnomAD-4.0.0	2.72645E-05
11	6	P/S	7	rs775206165	0.1582	None	gnomAD-2.1.1	2.83E-05
11	6	P/S	7	rs775206165	0.1582	None	gnomAD-3.1.2	6.57E-06
11	6	P/S	7	rs775206165	0.1582	None	gnomAD-4.0.0	9.29457E-06
12	7	L/S	8	None	0.0895	None	gnomAD-4.0.0	1.20032E-06
14	9	S/I	11	rs771027745	0.0876	None	gnomAD-2.1.1	3.98E-06
14	9	S/I	11	rs771027745	0.0876	None	gnomAD-4.0.0	5.47299E-06
14	9	S/N	11	rs771027745	0.0876	None	gnomAD-4.0.0	6.84124E-07
15	10	V/A	13	rs1471462382	0.1240	None	gnomAD-2.1.1	1.19E-05
15	10	V/A	13	rs1471462382	0.1240	None	gnomAD-4.0.0	4.10473E-06
15	10	V/I	13	rs201857541	0.1240	None	gnomAD-2.1.1	1.48668E-04
15	10	V/I	13	rs201857541	0.1240	None	gnomAD-3.1.2	1.11741E-04
15	10	V/I	13	rs201857541	0.1240	None	1000 genomes	1.99681E-04
15	10	V/I	13	rs201857541	0.1240	None	gnomAD-4.0.0	9.23189E-05
16	11	V/M	14	rs756212082	0.2320	None	gnomAD-2.1.1	2.12E-05
16	11	V/M	14	rs756212082	0.2320	None	gnomAD-3.1.2	1.97E-05
16	11	V/M	14	rs756212082	0.2320	None	gnomAD-4.0.0	2.04472E-05
17	12	V/A	16	None	0.1199	None	gnomAD-4.0.0	1.20032E-06
17	12	V/I	16	None	0.1199	None	gnomAD-4.0.0	1.20032E-06
18	13	L/R	18	rs748322000	0.2207	None	gnomAD-2.1.1	7.08E-06
18	13	L/R	18	rs748322000	0.2207	None	gnomAD-3.1.2	2.63E-05
18	13	L/R	18	rs748322000	0.2207	None	gnomAD-4.0.0	7.68421E-06
19	14	E/D	23	rs781416228	0.3034	None	gnomAD-2.1.1	3.98E-06
19	14	E/D	23	rs781416228	0.3034	None	gnomAD-4.0.0	2.05234E-06
19	14	E/G	23	rs954288080	0.3034	None	gnomAD-2.1.1	3.98E-06
19	14	E/G	23	rs954288080	0.3034	None	gnomAD-4.0.0	1.59072E-06
20	15	G/D	24	None	0.3496	None	gnomAD-4.0.0	1.20032E-06
21	16	S/T	25	rs1211610408	0.2626	None	gnomAD-2.1.1	3.98E-06
21	16	S/T	25	rs1211610408	0.2626	None	gnomAD-4.0.0	6.84119E-07
22	17	T/A	26	rs1305775594	0.3704	None	gnomAD-2.1.1	3.98E-06
22	17	T/A	26	rs1305775594	0.3704	None	gnomAD-4.0.0	6.84113E-07
22	17	T/I	26	None	0.3704	None	gnomAD-4.0.0	6.84117E-07
23	18	A/T	28	rs147812158	0.1097	None	gnomAD-2.1.1	3.98E-06
23	18	A/T	28	rs147812158	0.1097	None	gnomAD-3.1.2	1.97E-05
23	18	A/T	28	rs147812158	0.1097	None	gnomAD-4.0.0	9.29486E-06
24	19	T/I	29	rs536235994	0.3062	None	gnomAD-2.1.1	7.97E-06
24	19	T/I	29	rs536235994	0.3062	None	gnomAD-3.1.2	6.57E-06
24	19	T/I	29	rs536235994	0.3062	None	gnomAD-4.0.0	4.33741E-06
24	19	T/N	29	None	0.3062	None	gnomAD-2.1.1	1.59E-05
24	19	T/N	29	None	0.3062	None	gnomAD-3.1.2	1.31E-05
24	19	T/N	29	None	0.3062	None	gnomAD-4.0.0	1.05337E-05
24	19	T/P	29	rs758953324	0.3062	None	gnomAD-2.1.1	1.19E-05
24	19	T/P	29	rs758953324	0.3062	None	gnomAD-4.0.0	6.15713E-06
24	19	T/S	29	rs536235994	0.3062	None	gnomAD-2.1.1	7.97E-06
24	19	T/S	29	rs536235994	0.3062	None	gnomAD-4.0.0	1.16301E-05
25	20	F/V	30	None	0.0893	None	gnomAD-4.0.0	2.40064E-06
27	22	A/V	33	rs760167840	0.1099	None	gnomAD-2.1.1	1.2E-05
27	22	A/V	33	rs760167840	0.1099	None	gnomAD-3.1.2	1.97E-05
27	22	A/V	33	rs760167840	0.1099	None	gnomAD-4.0.0	8.96567E-06
28	23	H/D	34	rs752309578	0.3386	None	gnomAD-2.1.1	3.98E-06
28	23	H/Y	34	None	0.3386	None	gnomAD-4.0.0	1.20036E-06
29	24	I/F	35	None	0.1205	None	gnomAD-4.0.0	1.36834E-06
29	24	I/V	35	rs1458992819	0.1205	None	gnomAD-2.1.1	3.98E-06
29	24	I/V	35	rs1458992819	0.1205	None	gnomAD-4.0.0	3.42086E-06
30	25	S/N	38	rs767153909	0.3222	None	gnomAD-2.1.1	3.99E-06
30	25	S/N	38	rs767153909	0.3222	None	gnomAD-4.0.0	8.21017E-06
31	26	G/D	40	None	0.1281	None	gnomAD-4.0.0	1.59167E-06
35	30	P/A	44	rs779420414	0.1113	None	gnomAD-2.1.1	1.6E-05
35	30	P/A	44	rs779420414	0.1113	None	gnomAD-4.0.0	6.36349E-06
35	30	P/L	44	rs755605142	0.1113	None	gnomAD-2.1.1	7.97E-06
35	30	P/L	44	rs755605142	0.1113	None	gnomAD-4.0.0	3.18161E-06
35	30	P/T	44	rs779420414	0.1113	None	gnomAD-2.1.1	3.99E-06
35	30	P/T	44	rs779420414	0.1113	None	gnomAD-3.1.2	6.57E-06
35	30	P/T	44	rs779420414	0.1113	None	gnomAD-4.0.0	6.57082E-06
36	31	E/K	45	rs2094110497	0.5781	None	gnomAD-4.0.0	1.59079E-06
37	32	V/G	46	None	0.2348	None	gnomAD-4.0.0	1.08131E-05
38	33	S/N	47	None	0.2794	None	gnomAD-4.0.0	1.59066E-06
38	33	S/R	47	None	0.2794	None	gnomAD-4.0.0	1.59063E-06
40	35	F/V	49	None	0.2037	None	gnomAD-4.0.0	1.59061E-06
42	37	D/E	51	None	0.4139	None	gnomAD-4.0.0	1.20032E-06
42	37	D/G	51	rs200838218	0.4139	None	gnomAD-2.1.1	3.98E-06
42	37	D/G	51	rs200838218	0.4139	None	gnomAD-4.0.0	2.05223E-06
42	37	D/N	51	rs759317260	0.4139	None	gnomAD-2.1.1	3.98E-06
42	37	D/N	51	rs759317260	0.4139	None	gnomAD-3.1.2	6.57E-06
42	37	D/N	51	rs759317260	0.4139	None	gnomAD-4.0.0	1.85874E-06
43	38	G/C	52	None	0.3072	None	gnomAD-4.0.0	2.40064E-06
44	39	Q/L	55	rs867308852	0.4576	None	gnomAD-2.1.1	2.79E-05
44	39	Q/L	55	rs867308852	0.4576	None	gnomAD-3.1.2	6.57E-06
44	39	Q/L	55	rs867308852	0.4576	None	gnomAD-4.0.0	5.57617E-06
44	39	Q/R	55	rs867308852	0.4576	None	gnomAD-3.1.2	6.57E-06
44	39	Q/R	55	rs867308852	0.4576	None	gnomAD-4.0.0	2.4783E-06
45	40	V/L	56	rs142028110	0.3429	None	gnomAD-2.1.1	2.83E-05
45	40	V/L	56	rs142028110	0.3429	None	gnomAD-3.1.2	4.6E-05
45	40	V/L	56	rs142028110	0.3429	None	gnomAD-4.0.0	6.84074E-07
45	40	V/M	56	None	0.3429	None	gnomAD-4.0.0	6.84074E-07
48	43	T/A	70	None	0.5006	None	gnomAD-4.0.0	2.73628E-06
48	43	T/I	70	rs1295047971	0.5006	None	gnomAD-2.1.1	3.98E-06
48	43	T/I	70	rs1295047971	0.5006	None	gnomAD-4.0.0	1.20032E-06
48	43	T/P	70	None	0.5006	None	gnomAD-4.0.0	6.84069E-07
49	44	S/F	73	rs368887734	0.6573	None	gnomAD-2.1.1	3.98E-06
49	44	S/F	73	rs368887734	0.6573	None	gnomAD-3.1.2	6.57E-06
49	44	S/F	73	rs368887734	0.6573	None	gnomAD-4.0.0	6.57004E-06
49	44	S/P	73	rs531066665	0.6573	None	gnomAD-2.1.1	1.19E-05
49	44	S/P	73	rs531066665	0.6573	None	gnomAD-3.1.2	6.57E-06
49	44	S/P	73	rs531066665	0.6573	None	1000 genomes	1.99681E-04
49	44	S/P	73	rs531066665	0.6573	None	gnomAD-4.0.0	3.40742E-05
49	44	S/Y	73	rs368887734	0.6573	None	gnomAD-3.1.2	1.97E-05
49	44	S/Y	73	rs368887734	0.6573	None	gnomAD-4.0.0	5.12205E-06
50	45	T/P	102	rs1217255349	0.3495	None	gnomAD-2.1.1	3.19E-05
50	45	T/P	102	rs1217255349	0.3495	None	gnomAD-3.1.2	1.32E-05
50	45	T/P	102	rs1217255349	0.3495	None	gnomAD-4.0.0	1.31744E-05
50	45	T/S	102	None	0.3495	None	gnomAD-4.0.0	1.20032E-06
51	46	L/R	103	rs868419744	0.1521	None	gnomAD-2.1.1	7.07E-06
51	46	L/R	103	rs868419744	0.1521	None	gnomAD-3.1.2	6.57E-06
51	46	L/R	103	rs868419744	0.1521	None	gnomAD-4.0.0	3.09775E-06
51	46	L/V	103	None	0.1521	None	gnomAD-4.0.0	6.84068E-07
52	47	P/R	111	rs761625399	0.5442	None	gnomAD-2.1.1	7.96E-06
52	47	P/R	111	rs761625399	0.5442	None	gnomAD-4.0.0	2.73627E-06
53	48	G/S	115	rs150902810	0.3300	None	gnomAD-2.1.1	3.18E-05
53	48	G/S	115	rs150902810	0.3300	None	gnomAD-3.1.2	1.31E-05
53	48	G/S	115	rs150902810	0.3300	None	1000 genomes	1.99681E-04
53	48	G/S	115	rs150902810	0.3300	None	gnomAD-4.0.0	7.43445E-06
53	48	G/V	115	None	0.3300	None	gnomAD-4.0.0	3.42034E-06
54	49	V/L	121	None	0.1610	None	gnomAD-4.0.0	4.10442E-06
54	49	V/M	121	rs139517732	0.1610	None	gnomAD-2.1.1	4.25E-05
54	49	V/M	121	rs139517732	0.1610	None	gnomAD-3.1.2	3.94E-05
54	49	V/M	121	rs139517732	0.1610	None	1000 genomes	5.99042E-04
54	49	V/M	121	rs139517732	0.1610	DCM	Literature	None
54	49	V/M	121	rs139517732	0.1610	None	gnomAD-4.0.0	3.71722E-05
55	50	Q/H	122	rs1561527314	0.6650	None	gnomAD-4.0.0	2.40064E-06
55	50	Q/R	122	None	0.6650	None	gnomAD-4.0.0	1.5905E-06
56	51	I/L	123	rs2094107740	0.3005	None	gnomAD-3.1.2	6.57E-06
56	51	I/L	123	rs2094107740	0.3005	None	gnomAD-4.0.0	6.57497E-06
57	52	S/F	125	rs1274297049	0.3546	None	gnomAD-3.1.2	6.57E-06
57	52	S/F	125	rs1274297049	0.3546	None	gnomAD-4.0.0	2.56112E-06
58	53	F/L	127	None	0.2430	None	gnomAD-4.0.0	1.5905E-06
59	54	S/R	130	rs191057824	0.3670	None	gnomAD-2.1.1	5.31E-05
59	54	S/R	130	rs191057824	0.3670	None	gnomAD-3.1.2	5.26E-05
59	54	S/R	130	rs191057824	0.3670	None	gnomAD-4.0.0	8.86006E-05
60	55	D/E	131	None	0.7091	None	gnomAD-4.0.0	2.05221E-06
60	55	D/N	131	rs35683768	0.7091	None	gnomAD-2.1.1	1.59E-05
60	55	D/N	131	rs35683768	0.7091	None	gnomAD-3.1.2	6.57E-06
60	55	D/N	131	rs35683768	0.7091	None	gnomAD-4.0.0	1.17724E-05
60	55	D/V	131	rs754533155	0.7091	None	gnomAD-2.1.1	3.98E-06
60	55	D/V	131	rs754533155	0.7091	None	gnomAD-4.0.0	1.59052E-06
60	55	D/Y	131	rs35683768	0.7091	None	gnomAD-2.1.1	1.46299E-02
60	55	D/Y	131	rs35683768	0.7091	None	gnomAD-3.1.2	2.60441E-02
60	55	D/Y	131	rs35683768	0.7091	None	1000 genomes	2.89537E-02
60	55	D/Y	131	rs35683768	0.7091	None	gnomAD-4.0.0	1.03547E-02
62	57	R/C	135	rs766108359	0.3101	None	gnomAD-2.1.1	1.19E-05
62	57	R/C	135	rs766108359	0.3101	None	gnomAD-4.0.0	4.10443E-06
62	57	R/G	135	None	0.3101	None	gnomAD-4.0.0	6.84071E-07
62	57	R/H	135	rs758169489	0.3101	None	gnomAD-2.1.1	7.78E-05
62	57	R/H	135	rs758169489	0.3101	None	gnomAD-3.1.2	3.95E-05
62	57	R/H	135	rs758169489	0.3101	None	gnomAD-4.0.0	1.85888E-05
63	58	A/T	136	rs764892312	0.0918	None	gnomAD-2.1.1	3.54E-05
63	58	A/T	136	rs764892312	0.0918	None	gnomAD-3.1.2	1.32E-05
63	58	A/T	136	rs764892312	0.0918	None	gnomAD-4.0.0	2.29267E-05
63	58	A/V	136	rs761823259	0.0918	None	gnomAD-2.1.1	3.98E-06
64	59	K/I	137	None	0.4257	None	gnomAD-4.0.0	1.59049E-06
65	60	L/V	138	None	0.0833	None	gnomAD-4.0.0	1.20034E-06
66	61	T/M	139	rs372755739	0.2025	None	gnomAD-2.1.1	4.24E-05
66	61	T/M	139	rs372755739	0.2025	None	gnomAD-3.1.2	3.94E-05
66	61	T/M	139	rs372755739	0.2025	None	gnomAD-4.0.0	4.58489E-05
67	62	I/N	140	rs952685437	0.1116	None	gnomAD-3.1.2	1.32E-05
67	62	I/N	140	rs952685437	0.1116	None	gnomAD-4.0.0	1.31546E-05
68	63	P/S	141	rs876658046	0.3781	None	gnomAD-3.1.2	6.57E-06
68	63	P/S	141	rs876658046	0.3781	None	gnomAD-4.0.0	9.2937E-06
69	64	A/T	143	rs1370693255	0.3893	None	gnomAD-2.1.1	1.77E-05
69	64	A/T	143	rs1370693255	0.3893	None	gnomAD-3.1.2	1.97E-05
69	64	A/T	143	rs1370693255	0.3893	None	gnomAD-4.0.0	1.11525E-05
70	65	V/A	144	None	0.0848	None	gnomAD-4.0.0	1.20036E-06
70	65	V/M	144	rs772248060	0.0848	None	gnomAD-2.1.1	4.77E-05
70	65	V/M	144	rs772248060	0.0848	None	gnomAD-3.1.2	4.6E-05
70	65	V/M	144	rs772248060	0.0848	None	gnomAD-4.0.0	2.41631E-05
71	66	T/N	145	None	0.3214	None	gnomAD-4.0.0	1.20037E-06
72	67	K/E	146	None	0.3001	None	gnomAD-4.0.0	2.05223E-06
72	67	K/T	146	rs1200039660	0.3001	None	gnomAD-2.1.1	3.98E-06
73	68	A/G	148	None	0.4476	None	gnomAD-4.0.0	6.84057E-07
74	69	N/K	149	rs2094104209	0.1960	None	gnomAD-4.0.0	1.20032E-06
74	69	N/S	149	rs774795341	0.1960	None	gnomAD-2.1.1	3.98E-06
74	69	N/S	149	rs774795341	0.1960	None	gnomAD-4.0.0	8.20886E-06
76	71	G/A	152	rs138750421	0.1449	None	gnomAD-2.1.1	9.9E-05
76	71	G/A	152	rs138750421	0.1449	None	gnomAD-3.1.2	1.11723E-04
76	71	G/A	152	rs138750421	0.1449	None	gnomAD-4.0.0	8.24034E-05
76	71	G/R	152	rs771137064	0.1449	None	gnomAD-4.0.0	3.18088E-06
76	71	G/V	152	rs138750421	0.1449	None	gnomAD-2.1.1	3.98E-06
76	71	G/V	152	rs138750421	0.1449	None	gnomAD-4.0.0	6.84065E-07
77	72	R/Q	153	rs727503709	0.4558	None	gnomAD-2.1.1	7.96E-06
77	72	R/Q	153	rs727503709	0.4558	None	gnomAD-4.0.0	4.10435E-06
78	73	Y/H	154	None	0.0963	None	gnomAD-4.0.0	1.59044E-06
79	74	S/F	155	None	0.1503	None	gnomAD-4.0.0	2.73624E-06
79	74	S/T	155	rs746487470	0.1503	None	gnomAD-2.1.1	3.98E-06
79	74	S/T	155	rs746487470	0.1503	None	gnomAD-4.0.0	1.59045E-06
79	74	S/Y	155	None	0.1503	None	gnomAD-4.0.0	6.8406E-07
82	77	A/D	158	None	0.0799	CFTD	Literature	None
82	77	A/T	158	rs1575010544	0.0799	None	gnomAD-3.1.2	6.57E-06
82	77	A/T	158	rs1575010544	0.0799	None	gnomAD-4.0.0	3.09756E-06
84	79	N/D	161	rs1349693054	0.1299	None	gnomAD-2.1.1	3.98E-06
84	79	N/D	161	rs1349693054	0.1299	None	gnomAD-4.0.0	1.59045E-06
84	79	N/K	161	rs142851233	0.1299	None	gnomAD-2.1.1	3.98E-06
84	79	N/K	161	rs142851233	0.1299	None	gnomAD-3.1.2	6.57E-06
84	79	N/K	161	rs142851233	0.1299	None	gnomAD-4.0.0	6.5722E-06
84	79	N/S	161	rs912344670	0.1299	None	gnomAD-3.1.2	6.57E-06
84	79	N/S	161	rs912344670	0.1299	None	gnomAD-4.0.0	2.47828E-06
85	80	G/E	162	rs758092470	0.4452	None	gnomAD-2.1.1	3.98E-06
85	80	G/E	162	rs758092470	0.4452	None	gnomAD-4.0.0	1.59047E-06
86	81	S/F	163	None	0.1127	None	gnomAD-4.0.0	1.59046E-06
86	81	S/Y	163	rs749985986	0.1127	None	gnomAD-2.1.1	3.98E-06
86	81	S/Y	163	rs749985986	0.1127	None	gnomAD-3.1.2	6.57E-06
86	81	S/Y	163	rs749985986	0.1127	None	gnomAD-4.0.0	6.57082E-06
87	82	G/R	164	rs756996890	0.1019	None	gnomAD-2.1.1	7.95E-06
87	82	G/R	164	rs756996890	0.1019	None	gnomAD-4.0.0	1.36819E-06
87	82	G/V	164	None	0.1019	None	gnomAD-4.0.0	1.36819E-06
88	83	Q/E	165	None	0.3654	None	gnomAD-4.0.0	1.2004E-06
89	84	A/G	166	rs200165636	0.0757	None	gnomAD-2.1.1	1.37894E-04
89	84	A/G	166	rs200165636	0.0757	None	gnomAD-3.1.2	1.24862E-04
89	84	A/G	166	rs200165636	0.0757	None	gnomAD-4.0.0	2.16237E-04
89	84	A/T	166	rs1259283214	0.0757	None	gnomAD-4.0.0	1.20039E-06
89	84	A/V	166	rs200165636	0.0757	None	gnomAD-2.1.1	7.95E-06
89	84	A/V	166	rs200165636	0.0757	None	gnomAD-3.1.2	1.97E-05
89	84	A/V	166	rs200165636	0.0757	None	gnomAD-4.0.0	8.05467E-06
90	85	T/A	168	None	0.2123	None	gnomAD-4.0.0	1.59048E-06
91	86	S/I	169	rs1367815458	0.0588	None	gnomAD-3.1.2	6.57E-06
91	86	S/I	169	rs1367815458	0.0588	None	gnomAD-4.0.0	6.57186E-06
91	86	S/N	169	None	0.0588	None	gnomAD-4.0.0	1.20038E-06
91	86	S/T	169	None	0.0588	None	gnomAD-4.0.0	3.60113E-06
92	87	T/A	171	rs767442718	0.1489	None	gnomAD-2.1.1	3.98E-06
92	87	T/A	171	rs767442718	0.1489	None	gnomAD-3.1.2	6.57E-06
92	87	T/A	171	rs767442718	0.1489	None	gnomAD-4.0.0	2.56113E-06
92	87	T/S	171	rs767442718	0.1489	None	gnomAD-2.1.1	3.98E-06
92	87	T/S	171	rs767442718	0.1489	None	gnomAD-4.0.0	1.5905E-06
93	88	A/S	172	None	0.0659	None	gnomAD-4.0.0	2.05225E-06
93	88	A/T	172	rs1575009860	0.0659	None	gnomAD-4.0.0	2.05225E-06
93	88	A/V	172	rs1473207810	0.0659	None	gnomAD-2.1.1	3.98E-06
93	88	A/V	172	rs1473207810	0.0659	None	gnomAD-4.0.0	1.59052E-06
94	89	E/D	173	None	0.2008	None	gnomAD-4.0.0	6.84081E-07
95	90	L/F	174	rs774434865	0.0891	None	gnomAD-2.1.1	3.98E-06
95	90	L/F	174	rs774434865	0.0891	None	gnomAD-3.1.2	6.57E-06
95	90	L/F	174	rs774434865	0.0891	None	gnomAD-4.0.0	2.56115E-06
97	92	V/L	177	None	0.0860	None	gnomAD-4.0.0	6.84083E-07
97	92	V/M	177	rs185921345	0.0860	None	gnomAD-2.1.1	2.59558E-03
97	92	V/M	177	rs185921345	0.0860	None	gnomAD-3.1.2	1.99132E-03
97	92	V/M	177	rs185921345	0.0860	None	1000 genomes	1.19808E-03
97	92	V/M	177	rs185921345	0.0860	None	gnomAD-4.0.0	1.17342E-03

Position	Domain position	SAV	RS	Q(SASA)	Source	Structural Position	Disease	AlphaMissense (IC)	AlphaMissense (N2AB)	CADD	Condel	DUET	FATHMM	M-CAP	mCSM	MetaLR	MetaSVM	MPC	MutationAssessor	MutationTaster	MutPred	MVP	PolyPhen-2	PrimateAI	PROVEAN	REVEL	Rhapsody	SIFT	Zygosity	Comments	MAF	AFR	AMR	AMS	ASJ	EAS	EUR	FIN	MDE	NFE	SAS	OTH	Site Annotation	Predicted PPI	mCSM-PPI
6	1	P/L	rs201490999	0.1070	gnomAD-2.1.1	1	None	0.942	0.933	26.4	D	-0.477	-1.44	0.042701	-0.798	0.8134	0.8219	0.468442230762	None	0.999999	0.878	0.94644319945	1.0	0.737591207027	-6.39	0.556	0.885	None	None	None	1.2E-05	6.16E-05	0	0	0	None	0	None	1.2E-05	0	1.76E-05	0	None	N	-1.449(TCAP)
6	1	P/L	rs201490999	0.1070	gnomAD-3.1.2	1	None	0.942	0.933	26.4	D	-0.477	-1.44	0.042701	-0.798	0.8134	0.8219	0.468442230762	None	0.999999	0.878	0.94644319945	1.0	0.737591207027	-6.39	0.556	0.885	None	None	None	1.31E-05	2.41E-05	0	0	0	None	0	0	1.31E-05	1.47E-05	0	0	None	N	-1.449(TCAP)
6	1	P/L	rs201490999	0.1070	gnomAD-4.0.0	1	None	0.942	0.933	26.4	D	-0.477	-1.44	0.042701	-0.798	0.8134	0.8219	0.468442230762	None	0.999999	0.878	0.94644319945	1.0	0.737591207027	-6.39	0.556	0.885	None	None	None	3.53224E-05	4.00598E-05	1.66728E-05	0	0	None	0	0	3.53224E-05	4.40718E-05	0	1.60092E-05	None	N	-1.449(TCAP)
7	2	T/A	rs752073551	0.2046	gnomAD-2.1.1	2	None	0.0993	0.0847	23.4	N	-1.0	-0.21	0.023826	-0.611	0.1831	-0.5918	0.102063321427	None	0.682621	0.335	0.183819452728	0.017	0.517484545708	-2.72	0.209	0.385	0.134	None	None	7.97E-06	0	0	0	0	None	0	None	7.97E-06	4.62E-05	8.82E-06	0	None	N	-0.829(TCAP)
7	2	T/A	rs752073551	0.2046	gnomAD-4.0.0	2	None	0.0993	0.0847	23.4	N	-1.0	-0.21	0.023826	-0.611	0.1831	-0.5918	0.102063321427	None	0.682621	0.335	0.183819452728	0.017	0.517484545708	-2.72	0.209	0.385	0.134	None	None	1.59103E-06	0	0	0	0	None	1.88182E-05	0	1.59103E-06	0	0	0	None	N	-0.829(TCAP)
7	2	T/K	rs761344572	0.2046	gnomAD-2.1.1	2	None	0.2277	0.1794	24.1	N	-0.251	-0.13	0.025419	-0.198	0.1994	-0.3405	0.30783849951	None	0.932628	0.445	0.379366414296	0.915	0.602556347847	-3.23	0.397	0.48	0.094	None	None	3.98E-06	0	0	0	0	None	3.27E-05	None	3.98E-06	0	0	0	None	N	-1.585(TCAP)
7	2	T/K	rs761344572	0.2046	gnomAD-4.0.0	2	None	0.2277	0.1794	24.1	N	-0.251	-0.13	0.025419	-0.198	0.1994	-0.3405	0.30783849951	None	0.932628	0.445	0.379366414296	0.915	0.602556347847	-3.23	0.397	0.48	0.094	None	None	1.36833E-06	2.98757E-05	0	0	0	None	0	0	1.36833E-06	0	1.15988E-05	0	None	N	-1.585(TCAP)
7	2	T/M	rs761344572	0.2046	gnomAD-2.1.1	2	None	0.1336	0.1054	23.8	N	-0.151	-0.28	0.023899	-0.248	0.211	-0.491	0.11770967604	None	0.884587	0.365	0.49118058892	0.327	0.565551757812	-2.78	0.251	0.355	0.079	None	None	1.2E-05	0	2.89E-05	0	0	None	3.27E-05	None	1.2E-05	0	8.82E-06	0	None	N	-0.053(TCAP)
7	2	T/M	rs761344572	0.2046	gnomAD-4.0.0	2	None	0.1336	0.1054	23.8	N	-0.151	-0.28	0.023899	-0.248	0.211	-0.491	0.11770967604	None	0.884587	0.365	0.49118058892	0.327	0.565551757812	-2.78	0.251	0.355	0.079	None	None	1.29992E-05	0	2.23644E-05	0	2.51965E-05	None	0	0	1.29992E-05	9.89314E-06	3.47963E-05	4.96952E-05	None	N	-0.053(TCAP)
7	2	T/R	None	0.2046	gnomAD-4.0.0	2	None	0.1823	0.1351	26.0	N	None	-0.2	0.024586	-0.01	0.2424	-0.2676	0.454083579922	None	0.954036	0.404	0.531245695338	0.967	0.584919691086	-3.23	0.427	0.513	0.053	None	None	6.84166E-07	0	0	0	2.51965E-05	None	0	0	6.84166E-07	0	0	0	None	N	-1.392(TCAP)
8	3	F/I	None	0.1222	gnomAD-4.0.0	3	None	0.7673	0.6066	27.8	N	None	-0.38	0.04549	-1.434	0.4554	-0.0796	0.544725754754	None	0.994916	0.718	0.58541340546	1.0	0.786251544952	-3.83	0.606	0.781	0.038	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	-3.121(TCAP)
9	4	T/K	rs146123323	0.4320	gnomAD-3.1.2	4	None	0.0765	0.0699	21.8	N	None	0.93	0.06231	-0.746	0.2235	-0.8506	0.101150159241	None	0.994168	0.574	0.137902524267	None	0.407146662474	-3.63	0.132	0.177	0.113	None	None	6.57E-06	0	6.54E-05	0	0	None	0	0	6.57E-06	0	0	0	None	N	-0.538(TCAP)
9	4	T/K	rs146123323	0.4320	gnomAD-4.0.0	4	None	0.0765	0.0699	21.8	N	None	0.93	0.06231	-0.746	0.2235	-0.8506	0.101150159241	None	0.994168	0.574	0.137902524267	None	0.407146662474	-3.63	0.132	0.177	0.113	None	None	6.57134E-06	0	6.54279E-05	0	0	None	0	0	6.57134E-06	0	0	0	None	N	-0.538(TCAP)
9	4	T/M	rs146123323	0.4320	gnomAD-2.1.1	4	None	0.1146	0.0957	None	D	0.106	None	None	0.148	None	None	None	None	None	None	None	0.552	None	None	0.14	0.297	None	None	None	3.19E-05	1.84729E-04	5.78E-05	0	0	None	0	None	3.19E-05	0	1.76E-05	1.63506E-04	None	N	0.352(TCAP)
9	4	T/M	rs146123323	0.4320	gnomAD-3.1.2	4	None	0.1146	0.0957	None	D	0.106	None	None	0.148	None	None	None	None	None	None	None	0.552	None	None	0.14	0.297	None	None	None	2.63E-05	9.65E-05	0	0	0	None	0	0	2.63E-05	0	0	0	None	N	0.352(TCAP)
9	4	T/M	rs146123323	0.4320	gnomAD-4.0.0	4	None	0.1146	0.0957	None	D	0.106	None	None	0.148	None	None	None	None	None	None	None	0.552	None	None	0.14	0.297	None	None	None	1.05341E-05	9.3423E-05	5.00017E-05	0	0	None	1.56191E-05	0	1.05341E-05	3.39007E-06	0	3.20195E-05	None	N	0.352(TCAP)
9	4	T/S	rs1298028827	0.4320	gnomAD-2.1.1	4	None	0.139	0.1162	22.6	N	-0.703	0.93	0.051271	-0.874	0.1953	-0.8783	0.0750534160374	None	0.997487	0.462	0.199424873507	None	0.366252958775	-2.44	0.08	0.123	0.221	None	None	7.97E-06	0	0	0	0	None	0	None	7.97E-06	0	1.76E-05	0	None	N	-0.478(TCAP)
9	4	T/S	rs1298028827	0.4320	gnomAD-4.0.0	4	None	0.139	0.1162	22.6	N	-0.703	0.93	0.051271	-0.874	0.1953	-0.8783	0.0750534160374	None	0.997487	0.462	0.199424873507	None	0.366252958775	-2.44	0.08	0.123	0.221	None	None	2.73662E-06	0	0	0	0	None	0	0	2.73662E-06	3.59747E-06	0	0	None	N	-0.478(TCAP)
10	5	Q/H	None	0.2155	gnomAD-4.0.0	5	None	0.3457	0.2485	22.4	D	None	-0.45	0.023935	-0.748	0.4296	-0.1701	0.274510111426	None	0.999973	0.551	0.508163421412	0.754	0.682860851288	-3.19	0.403	0.349	0.134	None	None	1.59093E-06	0	0	0	0	None	0	0	1.59093E-06	2.85721E-06	0	0	None	N	-0.628(TCAP)
10	5	Q/R	None	0.2155	gnomAD-4.0.0	5	None	0.1412	0.114	24.0	N	None	-0.36	0.028656	-0.34	0.1829	-0.7624	0.133627313775	None	0.591915	0.477	0.198526703765	0.124	0.683910310268	-2.56	0.294	0.285	0.827	None	None	1.59096E-06	0	0	0	0	None	0	0	1.59096E-06	2.85726E-06	0	0	None	N	-1.612(TCAP)
11	6	P/A	None	0.1582	gnomAD-4.0.0	7	None	0.1536	0.1087	24.4	N	None	-0.23	0.020792	-0.967	0.3581	-0.3215	0.382567879333	None	0.999421	0.344	0.437314048365	0.985	0.76630461216	-5.11	0.392	0.65	0.018	None	None	1.36829E-06	0	0	0	0	None	0	0	1.36829E-06	0	2.31959E-05	0	None	N	-0.897(TCAP)
11	6	P/L	rs768624416	0.1582	gnomAD-2.1.1	7	None	0.3348	0.2157	None	N	-0.194	None	None	-0.396	None	None	None	None	None	None	None	0.97	None	None	0.477	0.494	None	None	None	7.97E-06	0	0	0	0	None	0	None	7.97E-06	0	1.76E-05	0	None	N	-0.668(TCAP)
11	6	P/L	rs768624416	0.1582	gnomAD-3.1.2	7	None	0.3348	0.2157	None	N	-0.194	None	None	-0.396	None	None	None	None	None	None	None	0.97	None	None	0.477	0.494	None	None	None	3.29E-05	7.24E-05	0	0	0	None	0	0	3.29E-05	2.94E-05	0	0	None	N	-0.668(TCAP)
11	6	P/L	rs768624416	0.1582	gnomAD-4.0.0	7	None	0.3348	0.2157	None	N	-0.194	None	None	-0.396	None	None	None	None	None	None	None	0.97	None	None	0.477	0.494	None	None	None	2.72645E-05	6.67468E-05	0	0	0	None	0	0	2.72645E-05	3.1358E-05	0	3.20195E-05	None	N	-0.668(TCAP)
11	6	P/S	rs775206165	0.1582	gnomAD-2.1.1	7	None	0.3023	0.1869	25.4	N	-0.855	-0.24	0.016847	-1.009	0.4274	-0.2375	0.456683706047	None	0.999644	0.284	0.482283251092	1.0	0.768000721931	-5.11	0.331	0.819	0.01	None	None	2.83E-05	0	2.25836E-04	0	0	None	0	None	2.83E-05	0	0	0	None	N	-0.359(TCAP)
11	6	P/S	rs775206165	0.1582	gnomAD-3.1.2	7	None	0.3023	0.1869	25.4	N	-0.855	-0.24	0.016847	-1.009	0.4274	-0.2375	0.456683706047	None	0.999644	0.284	0.482283251092	1.0	0.768000721931	-5.11	0.331	0.819	0.01	None	None	6.57E-06	0	6.55E-05	0	0	None	0	0	6.57E-06	0	0	0	None	N	-0.359(TCAP)
11	6	P/S	rs775206165	0.1582	gnomAD-4.0.0	7	None	0.3023	0.1869	25.4	N	-0.855	-0.24	0.016847	-1.009	0.4274	-0.2375	0.456683706047	None	0.999644	0.284	0.482283251092	1.0	0.768000721931	-5.11	0.331	0.819	0.01	None	None	9.29457E-06	0	1.66683E-04	0	0	None	0	0	9.29457E-06	3.39001E-06	0	1.60102E-05	None	N	-0.359(TCAP)
12	7	L/S	None	0.0895	gnomAD-4.0.0	8	None	0.926	0.9729	28.4	D	None	0.75	0.037971	-2.523	0.3848	0.1262	0.53274071128	None	0.605244	0.544	0.893473383505	1.0	0.725598692894	-3.83	0.479	0.848	0.001	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	-0.256(TCAP)
14	9	S/I	rs771027745	0.0876	gnomAD-2.1.1	11	None	0.6687	0.6255	24.0	N	0.169	0.88	0.015844	-0.008	0.2986	-0.5526	0.503965992592	None	0.998861	0.576	0.675737440431	1.0	0.741641223431	-3.8	0.397	0.802	0.025	None	None	3.98E-06	0	0	0	0	None	0	None	3.98E-06	0	8.81E-06	0	None	N	-0.816(TCAP)
14	9	S/I	rs771027745	0.0876	gnomAD-4.0.0	11	None	0.6687	0.6255	24.0	N	0.169	0.88	0.015844	-0.008	0.2986	-0.5526	0.503965992592	None	0.998861	0.576	0.675737440431	1.0	0.741641223431	-3.8	0.397	0.802	0.025	None	None	5.47299E-06	0	0	0	0	None	0	0	5.47299E-06	7.19472E-06	0	0	None	N	-0.816(TCAP)
14	9	S/N	rs771027745	0.0876	gnomAD-4.0.0	11	None	0.1838	0.175	23.5	N	None	1.03	0.011401	-0.251	0.1721	-0.7725	0.447973635636	None	0.992409	0.378	0.367425347029	0.998	0.752904891968	-1.87	0.295	0.593	0.791	None	None	6.84124E-07	0	0	0	0	None	0	0	6.84124E-07	8.9934E-07	0	0	None	N	-0.592(TCAP)
15	10	V/A	rs1471462382	0.1240	gnomAD-2.1.1	13	None	0.1498	0.1552	24.2	N	-0.906	-0.47	0.020394	-1.095	0.4024	-0.1379	0.480448835524	None	0.973202	0.692	0.793074248023	0.995	0.662272691727	-2.56	0.524	0.476	0.356	None	None	1.19E-05	0	5.78E-05	0	0	None	3.27E-05	None	1.19E-05	0	0	0	None	N	-0.798(TCAP)
15	10	V/A	rs1471462382	0.1240	gnomAD-4.0.0	13	None	0.1498	0.1552	24.2	N	-0.906	-0.47	0.020394	-1.095	0.4024	-0.1379	0.480448835524	None	0.973202	0.692	0.793074248023	0.995	0.662272691727	-2.56	0.524	0.476	0.356	None	None	4.10473E-06	0	4.47227E-05	0	0	None	0	0	4.10473E-06	2.69801E-06	1.15969E-05	0	None	N	-0.798(TCAP)
15	10	V/I	rs201857541	0.1240	gnomAD-2.1.1	13	None	0.092	0.0905	None	N	0.073	None	None	-0.232	None	None	None	None	None	None	None	0.681	None	None	0.269	0.257	None	None	None	1.48668E-04	0	8.47E-05	5.79486E-04	5.02E-05	None	4.25059E-04	None	1.48668E-04	0	1.47342E-04	0	None	N	-1.001(TCAP)
15	10	V/I	rs201857541	0.1240	gnomAD-3.1.2	13	None	0.092	0.0905	None	N	0.073	None	None	-0.232	None	None	None	None	None	None	None	0.681	None	None	0.269	0.257	None	None	None	1.11741E-04	0	1.30907E-04	0	0	None	0	0	1.11741E-04	1.76393E-04	6.21891E-04	0	None	N	-1.001(TCAP)
15	10	V/I	rs201857541	0.1240	1000 genomes	13	None	0.092	0.0905	None	N	0.073	None	None	-0.232	None	None	None	None	None	None	None	0.681	None	None	0.269	0.257	None	None	None	1.99681E-04	0	0	None	0	0	None	None	1.99681E-04	None	1E-03	None	None	N	-1.001(TCAP)
15	10	V/I	rs201857541	0.1240	gnomAD-4.0.0	13	None	0.092	0.0905	None	N	0.073	None	None	-0.232	None	None	None	None	None	None	None	0.681	None	None	0.269	0.257	None	None	None	9.23189E-05	2.66553E-05	8.33111E-05	4.72941E-04	2.22886E-05	None	4.68691E-05	0	9.23189E-05	7.03422E-05	3.73438E-04	1.12014E-04	None	N	-1.001(TCAP)
16	11	V/M	rs756212082	0.2320	gnomAD-2.1.1	14	None	0.1888	0.1711	None	N	-0.29	None	None	-0.488	None	None	None	None	None	None	None	1.0	None	None	0.334	0.631	None	None	None	2.12E-05	0	0	0	0	None	3.27E-05	None	2.12E-05	0	3.1E-05	1.38696E-04	None	N	0.059(TCAP)
16	11	V/M	rs756212082	0.2320	gnomAD-3.1.2	14	None	0.1888	0.1711	None	N	-0.29	None	None	-0.488	None	None	None	None	None	None	None	1.0	None	None	0.334	0.631	None	None	None	1.97E-05	0	0	0	0	None	0	0	1.97E-05	4.41E-05	0	0	None	N	0.059(TCAP)
16	11	V/M	rs756212082	0.2320	gnomAD-4.0.0	14	None	0.1888	0.1711	None	N	-0.29	None	None	-0.488	None	None	None	None	None	None	None	1.0	None	None	0.334	0.631	None	None	None	2.04472E-05	0	0	0	0	None	0	0	2.04472E-05	2.54245E-05	1.09818E-05	3.20154E-05	None	N	0.059(TCAP)
17	12	V/A	None	0.1199	gnomAD-4.0.0	16	None	0.2775	0.2606	22.6	D	None	-0.44	0.081239	-1.569	0.2277	-0.6122	0.101606500328	None	0.755855	0.811	0.569949186141	None	0.525764703751	-1.04	0.248	0.101	0.899	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	-0.448(TCAP)
17	12	V/I	None	0.1199	gnomAD-4.0.0	16	None	0.1235	0.1239	22.3	D	None	-0.47	0.052275	-0.525	0.3591	-0.2576	0.0743878876887	None	0.993711	0.68	0.639750416835	0.042	0.405120491982	-0.64	0.408	0.42	0.185	None	None	1.20032E-06	0	0	0	2.75482E-04	None	0	0	1.20032E-06	0	0	0	None	N	-0.787(TCAP)
18	13	L/R	rs748322000	0.2207	gnomAD-2.1.1	18	None	0.3069	0.2825	None	N	-0.002	None	None	0.104	None	None	None	None	None	None	None	1.0	None	None	0.593	0.719	None	None	None	7.08E-06	8.01E-05	0	0	0	None	0	None	7.08E-06	0	0	0	None	N	-1.227(TCAP)
18	13	L/R	rs748322000	0.2207	gnomAD-3.1.2	18	None	0.3069	0.2825	None	N	-0.002	None	None	0.104	None	None	None	None	None	None	None	1.0	None	None	0.593	0.719	None	None	None	2.63E-05	9.65E-05	0	0	0	None	0	0	2.63E-05	0	0	0	None	N	-1.227(TCAP)
18	13	L/R	rs748322000	0.2207	gnomAD-4.0.0	18	None	0.3069	0.2825	None	N	-0.002	None	None	0.104	None	None	None	None	None	None	None	1.0	None	None	0.593	0.719	None	None	None	7.68421E-06	1.01461E-04	0	0	0	None	0	0	7.68421E-06	0	0	0	None	N	-1.227(TCAP)
19	14	E/D	rs781416228	0.3034	gnomAD-2.1.1	23	None	0.5888	0.5631	24.1	N	-1.446	0.76	0.015601	-0.628	0.3199	-0.4941	0.414142546602	None	0.994345	0.476	0.560989807984	0.979	0.619923114777	-1.92	0.361	0.446	0.133	None	None	3.98E-06	0	0	0	0	None	0	None	3.98E-06	0	8.81E-06	0	None	N	-0.766(TCAP)
19	14	E/D	rs781416228	0.3034	gnomAD-4.0.0	23	None	0.5888	0.5631	24.1	N	-1.446	0.76	0.015601	-0.628	0.3199	-0.4941	0.414142546602	None	0.994345	0.476	0.560989807984	0.979	0.619923114777	-1.92	0.361	0.446	0.133	None	None	2.05234E-06	0	0	0	0	None	0	0	2.05234E-06	2.69797E-06	0	0	None	N	-0.766(TCAP)
19	14	E/G	rs954288080	0.3034	gnomAD-2.1.1	23	None	0.6028	0.5663	26.9	D	None	0.75	0.051674	-1.165	0.4361	0.1214	0.499973522767	None	0.992695	0.54	0.621312436561	1.0	0.584666132927	-4.47	0.522	0.639	0.061	None	None	3.98E-06	0	0	0	5.45E-05	None	0	None	3.98E-06	0	0	0	None	N	-0.793(TCAP)
19	14	E/G	rs954288080	0.3034	gnomAD-4.0.0	23	None	0.6028	0.5663	26.9	D	None	0.75	0.051674	-1.165	0.4361	0.1214	0.499973522767	None	0.992695	0.54	0.621312436561	1.0	0.584666132927	-4.47	0.522	0.639	0.061	None	None	1.59072E-06	0	0	0	0	None	0	0	1.59072E-06	0	0	3.02243E-05	None	N	-0.793(TCAP)
20	15	G/D	None	0.3496	gnomAD-4.0.0	24	None	0.3204	0.3637	24.5	D	None	-1.39	0.103098	-0.315	0.7372	0.7129	0.516736040293	None	0.975836	0.872	0.631643887469	1.0	0.731106519699	-4.47	0.773	0.825	None	None	None	1.20032E-06	0	0	0	0	None	0	6.17284E-04	1.20032E-06	0	0	0	None	N	0.072(TCAP)
21	16	S/T	rs1211610408	0.2626	gnomAD-2.1.1	25	None	0.1437	0.1398	24.0	N	-0.311	0.94	0.01683	-0.328	0.2515	-0.6958	0.416335992142	None	0.990458	0.415	0.533179623451	0.966	0.585834980011	-1.9	0.291	0.425	0.094	None	None	3.98E-06	0	0	0	0	None	3.27E-05	None	3.98E-06	0	0	0	None	N	-0.542(TCAP)
21	16	S/T	rs1211610408	0.2626	gnomAD-4.0.0	25	None	0.1437	0.1398	24.0	N	-0.311	0.94	0.01683	-0.328	0.2515	-0.6958	0.416335992142	None	0.990458	0.415	0.533179623451	0.966	0.585834980011	-1.9	0.291	0.425	0.094	None	None	6.84119E-07	0	0	0	0	None	0	0	6.84119E-07	0	1.15977E-05	0	None	N	-0.542(TCAP)
22	17	T/A	rs1305775594	0.3704	gnomAD-2.1.1	26	None	0.074	0.0759	21.0	N	-0.498	0.9	0.035983	-0.642	0.08	-0.9799	0.0817590803949	None	0.988609	0.352	0.126345400529	None	0.337896972895	-0.9	0.122	0.098	0.548	None	None	3.98E-06	0	0	0	5.45E-05	None	0	None	3.98E-06	0	0	0	None	N	0.009(TCAP)
22	17	T/A	rs1305775594	0.3704	gnomAD-4.0.0	26	None	0.074	0.0759	21.0	N	-0.498	0.9	0.035983	-0.642	0.08	-0.9799	0.0817590803949	None	0.988609	0.352	0.126345400529	None	0.337896972895	-0.9	0.122	0.098	0.548	None	None	6.84113E-07	0	0	0	2.51991E-05	None	0	0	6.84113E-07	0	0	0	None	N	0.009(TCAP)
22	17	T/I	None	0.3704	gnomAD-4.0.0	26	None	0.1913	0.2117	23.4	D	None	0.86	0.041474	-0.23	0.2092	-0.6562	0.0940497116312	None	0.984121	0.489	0.411001663086	0.166	0.424367308617	-2.56	0.429	0.326	0.062	None	None	6.84117E-07	0	0	0	0	None	0	0	6.84117E-07	0	1.1598E-05	0	None	N	0.013(TCAP)
23	18	A/T	rs147812158	0.1097	gnomAD-2.1.1	28	None	0.2333	0.2522	None	D	-1.267	None	None	-1.168	None	None	None	None	None	None	None	1.0	None	None	0.432	0.709	None	None	None	3.98E-06	6.16E-05	0	0	0	None	0	None	3.98E-06	0	0	0	None	N	-1.279(TCAP)
23	18	A/T	rs147812158	0.1097	gnomAD-3.1.2	28	None	0.2333	0.2522	None	D	-1.267	None	None	-1.168	None	None	None	None	None	None	None	1.0	None	None	0.432	0.709	None	None	None	1.97E-05	2.41E-05	6.55E-05	0	0	None	0	0	1.97E-05	1.47E-05	0	0	None	N	-1.279(TCAP)
23	18	A/T	rs147812158	0.1097	gnomAD-4.0.0	28	None	0.2333	0.2522	None	D	-1.267	None	None	-1.168	None	None	None	None	None	None	None	1.0	None	None	0.432	0.709	None	None	None	9.29486E-06	1.33522E-05	1.66722E-05	0	1.55999E-04	None	0	0	9.29486E-06	4.23748E-06	1.09849E-05	0	None	N	-1.279(TCAP)
24	19	T/I	rs536235994	0.3062	gnomAD-2.1.1	29	None	0.1442	0.1455	27.6	N	0.134	0.88	0.015031	-0.164	0.2043	-0.7881	0.480749730577	None	0.999704	0.451	0.582733548269	1.0	0.596574425697	-3.83	0.477	0.793	0.082	None	None	7.97E-06	0	0	0	0	None	3.27E-05	None	7.97E-06	0	8.81E-06	0	None	N	-0.166(TCAP)
24	19	T/I	rs536235994	0.3062	gnomAD-3.1.2	29	None	0.1442	0.1455	27.6	N	0.134	0.88	0.015031	-0.164	0.2043	-0.7881	0.480749730577	None	0.999704	0.451	0.582733548269	1.0	0.596574425697	-3.83	0.477	0.793	0.082	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	-0.166(TCAP)
24	19	T/I	rs536235994	0.3062	gnomAD-4.0.0	29	None	0.1442	0.1455	27.6	N	0.134	0.88	0.015031	-0.164	0.2043	-0.7881	0.480749730577	None	0.999704	0.451	0.582733548269	1.0	0.596574425697	-3.83	0.477	0.793	0.082	None	None	4.33741E-06	0	0	0	0	None	0	0	4.33741E-06	5.08487E-06	1.09844E-05	0	None	N	-0.166(TCAP)
24	19	T/N	None	0.3062	gnomAD-2.1.1	29	None	0.1564	0.1488	26.8	N	-0.249	0.83	0.011633	-0.66	0.3117	-0.5419	0.494036468914	None	0.999709	0.445	0.568214726415	0.999	0.559471726418	-3.19	0.386	0.742	0.151	None	None	1.59E-05	0	2.89E-05	0	5.45E-05	None	0	None	1.59E-05	0	8.81E-06	1.63239E-04	None	N	-0.757(TCAP)
24	19	T/N	None	0.3062	gnomAD-3.1.2	29	None	0.1564	0.1488	26.8	N	-0.249	0.83	0.011633	-0.66	0.3117	-0.5419	0.494036468914	None	0.999709	0.445	0.568214726415	0.999	0.559471726418	-3.19	0.386	0.742	0.151	None	None	1.31E-05	0	0	0	0	None	0	0	1.31E-05	1.47E-05	2.07125E-04	0	None	N	-0.757(TCAP)
24	19	T/N	None	0.3062	gnomAD-4.0.0	29	None	0.1564	0.1488	26.8	N	-0.249	0.83	0.011633	-0.66	0.3117	-0.5419	0.494036468914	None	0.999709	0.445	0.568214726415	0.999	0.559471726418	-3.19	0.386	0.742	0.151	None	None	1.05337E-05	0	1.66678E-05	0	0	None	0	1.64366E-04	1.05337E-05	1.01697E-05	2.19688E-05	1.60067E-05	None	N	-0.757(TCAP)
24	19	T/P	rs758953324	0.3062	gnomAD-2.1.1	29	None	0.4755	0.4161	24.9	D	-0.384	0.79	0.028407	-0.368	0.3851	-0.1236	0.525743952474	None	0.998792	0.507	0.599805095821	0.999	0.490945309401	-3.83	0.448	0.791	0.123	None	None	1.19E-05	0	0	0	0	None	6.54E-05	None	1.19E-05	0	0	1.63292E-04	None	N	-0.15(TCAP)
24	19	T/P	rs758953324	0.3062	gnomAD-4.0.0	29	None	0.4755	0.4161	24.9	D	-0.384	0.79	0.028407	-0.368	0.3851	-0.1236	0.525743952474	None	0.998792	0.507	0.599805095821	0.999	0.490945309401	-3.83	0.448	0.791	0.123	None	None	6.15713E-06	0	0	0	0	None	0	0	6.15713E-06	0	1.04394E-04	0	None	N	-0.15(TCAP)
24	19	T/S	rs536235994	0.3062	gnomAD-2.1.1	29	None	0.1114	0.1101	24.1	N	-0.632	0.86	0.018273	-0.998	0.2395	-0.6257	0.433639850961	None	0.982056	0.399	0.389750110748	0.993	0.505296707153	-2.56	0.25	0.597	0.18	None	None	7.97E-06	0	5.79E-05	0	0	None	0	None	7.97E-06	0	0	0	None	N	-0.641(TCAP)
24	19	T/S	rs536235994	0.3062	gnomAD-4.0.0	29	None	0.1114	0.1101	24.1	N	-0.632	0.86	0.018273	-0.998	0.2395	-0.6257	0.433639850961	None	0.982056	0.399	0.389750110748	0.993	0.505296707153	-2.56	0.25	0.597	0.18	None	None	1.16301E-05	5.97372E-05	8.94494E-05	0	0	None	0	0	1.16301E-05	9.8926E-06	0	0	None	N	-0.641(TCAP)
25	20	F/V	None	0.0893	gnomAD-4.0.0	30	None	0.7318	0.7678	31.0	D	None	-0.82	0.096634	-0.805	0.6108	0.31	0.528971480179	None	0.997941	0.703	0.822178749166	1.0	0.655386149883	-4.47	0.689	0.767	0.008	None	None	2.40064E-06	0	0	0	0	None	0	0	2.40064E-06	0	6.07533E-05	3.66327E-05	None	N	-0.667(TCAP)
27	22	A/V	rs760167840	0.1099	gnomAD-2.1.1	33	None	0.4896	0.5266	27.2	N	-0.006	1.1	0.017428	-0.406	0.1604	-0.7604	0.4632225215	None	0.999902	0.681	0.638501922959	1.0	0.682771801949	-2.56	0.455	0.761	0.682	None	None	1.2E-05	6.16E-05	5.79E-05	0	0	None	0	None	1.2E-05	0	0	0	None	N	-0.942(TCAP)
27	22	A/V	rs760167840	0.1099	gnomAD-3.1.2	33	None	0.4896	0.5266	27.2	N	-0.006	1.1	0.017428	-0.406	0.1604	-0.7604	0.4632225215	None	0.999902	0.681	0.638501922959	1.0	0.682771801949	-2.56	0.455	0.761	0.682	None	None	1.97E-05	4.83E-05	6.54E-05	0	0	None	0	0	1.97E-05	0	0	0	None	N	-0.942(TCAP)
27	22	A/V	rs760167840	0.1099	gnomAD-4.0.0	33	None	0.4896	0.5266	27.2	N	-0.006	1.1	0.017428	-0.406	0.1604	-0.7604	0.4632225215	None	0.999902	0.681	0.638501922959	1.0	0.682771801949	-2.56	0.455	0.761	0.682	None	None	8.96567E-06	5.07408E-05	6.77828E-05	0	0	None	0	0	8.96567E-06	0	0	0	None	N	-0.942(TCAP)
28	23	H/D	rs752309578	0.3386	gnomAD-2.1.1	34	None	0.3085	0.2052	24.6	N	-0.664	-0.18	0.044947	-0.527	0.2402	-0.6137	0.150772647916	None	0.974254	0.332	0.35139820857	0.09	0.584686279297	-4.65	0.443	0.494	0.156	None	None	3.98E-06	0	0	0	0	None	0	None	3.98E-06	0	8.81E-06	0	None	N	-0.275(TCAP)
28	23	H/Y	None	0.3386	gnomAD-4.0.0	34	None	0.1445	0.1106	24.3	N	None	-0.25	0.027053	0.448	0.3782	-0.2819	0.207759020021	None	0.937277	0.403	0.472663046089	0.846	0.589715540409	-3.17	0.315	0.481	0.276	None	None	1.20036E-06	0	0	0	0	None	0	0	1.20036E-06	1.31254E-06	0	0	None	N	0.173(TCAP)
29	24	I/F	None	0.1205	gnomAD-4.0.0	35	None	0.7372	0.6049	20.3	N	None	-0.5	0.049731	-1.398	0.3752	-0.1979	0.271339168902	None	0.700659	0.545	0.32714864917	0.771	0.354283183813	-2.56	0.414	0.765	0.003	None	None	1.36834E-06	0	0	0	0	None	0	0	1.36834E-06	1.79873E-06	0	0	None	N	-1.048(TCAP)
29	24	I/V	rs1458992819	0.1205	gnomAD-2.1.1	35	None	0.0932	0.085	17.51	N	-1.367	0.17	0.047341	-1.267	0.0727	-1.0121	0.0704899027279	None	0.996986	0.434	0.144782658237	None	0.29144719243	-0.09	0.18	0.243	0.541	None	None	3.98E-06	0	0	0	0	None	0	None	3.98E-06	0	8.81E-06	0	None	N	-0.801(TCAP)
29	24	I/V	rs1458992819	0.1205	gnomAD-4.0.0	35	None	0.0932	0.085	17.51	N	-1.367	0.17	0.047341	-1.267	0.0727	-1.0121	0.0704899027279	None	0.996986	0.434	0.144782658237	None	0.29144719243	-0.09	0.18	0.243	0.541	None	None	3.42086E-06	0	0	0	0	None	3.74434E-05	0	3.42086E-06	1.79873E-06	1.16042E-05	0	None	N	-0.801(TCAP)
30	25	S/N	rs767153909	0.3222	gnomAD-2.1.1	38	None	0.2694	0.2012	23.9	N	-0.568	-0.34	0.028079	-0.273	0.3475	-0.338	0.351425158729	None	0.993467	0.379	0.302793454619	0.995	0.660016536713	-1.92	0.307	0.538	0.009	None	None	3.99E-06	0	0	0	0	None	0	None	3.99E-06	0	8.81E-06	0	None	N	-0.652(TCAP)
30	25	S/N	rs767153909	0.3222	gnomAD-4.0.0	38	None	0.2694	0.2012	23.9	N	-0.568	-0.34	0.028079	-0.273	0.3475	-0.338	0.351425158729	None	0.993467	0.379	0.302793454619	0.995	0.660016536713	-1.92	0.307	0.538	0.009	None	None	8.21017E-06	1.19489E-04	0	0	0	None	0	0	8.21017E-06	6.29559E-06	0	1.65618E-05	None	N	-0.652(TCAP)
31	26	G/D	None	0.1281	gnomAD-4.0.0	40	None	0.984	0.9672	24.0	D	None	-1.28	0.032715	-0.496	0.8207	0.9083	0.527275360279	None	0.999976	0.879	0.646441920909	1.0	0.710875868797	-4.47	None	0.849	0.127	None	None	1.59167E-06	0	0	0	0	None	0	0	1.59167E-06	2.85838E-06	0	0	None	N	-1.557(TCAP)
35	30	P/A	rs779420414	0.1113	gnomAD-2.1.1	44	None	0.7278	0.6584	24.9	D	-2.045	-0.71	0.032413	-1.816	0.5906	0.2375	0.457628982806	None	0.998559	0.918	0.534907319155	1.0	0.693701922894	-5.11	0.705	0.789	0.061	None	None	1.6E-05	0	0	0	0	None	1.30745E-04	None	1.6E-05	0	0	0	None	N	-0.303(TCAP)
35	30	P/A	rs779420414	0.1113	gnomAD-4.0.0	44	None	0.7278	0.6584	24.9	D	-2.045	-0.71	0.032413	-1.816	0.5906	0.2375	0.457628982806	None	0.998559	0.918	0.534907319155	1.0	0.693701922894	-5.11	0.705	0.789	0.061	None	None	6.36349E-06	0	0	0	0	None	0	0	6.36349E-06	0	5.73197E-05	0	None	N	-0.303(TCAP)
35	30	P/L	rs755605142	0.1113	gnomAD-2.1.1	44	None	0.89	0.8671	26.5	D	-0.544	-0.57	0.03743	-0.646	0.6596	0.4927	0.469722267271	None	0.999999	0.904	0.837958248163	1.0	0.756549715996	-6.39	0.75	0.825	0.07	None	None	7.97E-06	0	0	0	0	None	0	None	7.97E-06	0	1.76E-05	0	None	N	-0.7(TCAP)
35	30	P/L	rs755605142	0.1113	gnomAD-4.0.0	44	None	0.89	0.8671	26.5	D	-0.544	-0.57	0.03743	-0.646	0.6596	0.4927	0.469722267271	None	0.999999	0.904	0.837958248163	1.0	0.756549715996	-6.39	0.75	0.825	0.07	None	None	3.18161E-06	0	0	0	0	None	0	0	3.18161E-06	5.7138E-06	0	0	None	N	-0.7(TCAP)
35	30	P/T	rs779420414	0.1113	gnomAD-2.1.1	44	None	0.919	0.8884	25.2	D	-2.156	-0.73	0.045351	-1.816	0.6404	0.4188	0.489810199868	None	0.999162	0.881	0.734031765732	1.0	0.730566263199	-5.11	0.801	0.836	0.028	None	None	3.99E-06	6.16E-05	0	0	0	None	0	None	3.99E-06	0	0	0	None	N	-0.325(TCAP)
35	30	P/T	rs779420414	0.1113	gnomAD-3.1.2	44	None	0.919	0.8884	25.2	D	-2.156	-0.73	0.045351	-1.816	0.6404	0.4188	0.489810199868	None	0.999162	0.881	0.734031765732	1.0	0.730566263199	-5.11	0.801	0.836	0.028	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	N	-0.325(TCAP)
35	30	P/T	rs779420414	0.1113	gnomAD-4.0.0	44	None	0.919	0.8884	25.2	D	-2.156	-0.73	0.045351	-1.816	0.6404	0.4188	0.489810199868	None	0.999162	0.881	0.734031765732	1.0	0.730566263199	-5.11	0.801	0.836	0.028	None	None	6.57082E-06	2.41278E-05	0	0	0	None	0	0	6.57082E-06	0	0	0	None	N	-0.325(TCAP)
36	31	E/K	rs2094110497	0.5781	gnomAD-4.0.0	45	None	0.2338	0.2227	25.8	N	None	-0.28	0.022254	0.229	0.3784	-0.2582	0.486089516762	None	0.999371	0.558	0.488407942198	0.996	0.741286039352	-2.56	0.517	0.657	0.206	None	None	1.59079E-06	0	2.28666E-05	0	0	None	0	0	1.59079E-06	0	0	0	None	N	-0.214(TCAP)
37	32	V/G	None	0.2348	gnomAD-4.0.0	46	None	0.8553	0.7972	25.7	D	None	-1.08	0.112217	-2.025	0.7828	0.8883	0.527292994097	None	1.0	0.832	0.942146901664	1.0	0.671016573906	-4.47	0.922	0.875	0.001	None	None	1.08131E-05	0	0	0	0	None	0	0	1.08131E-05	1.051E-05	0	3.66623E-05	None	N	-0.586(TCAP)
38	33	S/N	None	0.2794	gnomAD-4.0.0	47	None	0.2395	0.2259	21.5	N	None	-0.46	0.027263	-0.365	0.217	-0.5354	0.0833740660745	None	0.922801	0.537	0.191931220699	0.006	0.684289932251	-1.85	0.176	0.355	0.02	None	None	1.59066E-06	0	0	0	0	None	0	0	1.59066E-06	0	0	3.02151E-05	None	N	-0.686(TCAP)
38	33	S/R	None	0.2794	gnomAD-4.0.0	47	None	0.6374	0.6314	25.2	N	None	-0.44	0.031687	-0.201	0.3182	-0.287	0.452195566295	None	0.999437	0.567	0.594650670498	0.995	0.691471636295	-3.01	0.669	0.69	0.007	None	None	1.59063E-06	0	0	0	0	None	0	0	1.59063E-06	0	0	3.0217E-05	None	N	-0.206(TCAP)
40	35	F/V	None	0.2037	gnomAD-4.0.0	49	None	0.4403	0.4377	23.2	N	None	0.88	0.067635	-1.522	0.1899	-0.6218	0.328683231813	None	0.825526	0.768	0.783852337514	0.95	0.562507033348	-4.1	0.368	0.524	0.067	None	None	1.59061E-06	0	0	0	0	None	0	0	1.59061E-06	2.85657E-06	0	0	None	N	-0.887(TCAP)
42	37	D/E	None	0.4139	gnomAD-4.0.0	51	None	0.4364	0.473	24.3	N	None	0.78	0.021397	-0.387	0.3084	-0.3761	0.438398937775	None	0.984689	0.793	0.478451964739	0.996	0.665334761143	-2.51	0.476	0.418	0.087	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	-0.33(TCAP)
42	37	D/G	rs200838218	0.4139	gnomAD-2.1.1	51	None	0.3474	0.4098	25.4	N	-0.28	0.86	0.055016	-0.794	0.3112	-0.4003	0.528140260466	None	0.998533	0.819	0.463758542814	1.0	0.644790947437	-4.24	0.681	0.694	0.034	None	None	3.98E-06	6.15E-05	0	0	0	None	0	None	3.98E-06	0	0	0	None	N	-0.297(TCAP)
42	37	D/G	rs200838218	0.4139	gnomAD-4.0.0	51	None	0.3474	0.4098	25.4	N	-0.28	0.86	0.055016	-0.794	0.3112	-0.4003	0.528140260466	None	0.998533	0.819	0.463758542814	1.0	0.644790947437	-4.24	0.681	0.694	0.034	None	None	2.05223E-06	5.97372E-05	0	0	0	None	0	1.73491E-04	2.05223E-06	0	0	0	None	N	-0.297(TCAP)
42	37	D/N	rs759317260	0.4139	gnomAD-2.1.1	51	None	0.1841	0.2211	25.6	N	0.291	1.02	0.032417	-0.431	0.1986	-0.7602	0.457538867752	None	0.999125	0.808	0.389126455913	1.0	0.68532627821	-3.09	0.429	0.629	0.119	None	None	3.98E-06	0	0	0	0	None	3.27E-05	None	3.98E-06	0	0	0	None	N	-1.374(TCAP)
42	37	D/N	rs759317260	0.4139	gnomAD-3.1.2	51	None	0.1841	0.2211	25.6	N	0.291	1.02	0.032417	-0.431	0.1986	-0.7602	0.457538867752	None	0.999125	0.808	0.389126455913	1.0	0.68532627821	-3.09	0.429	0.629	0.119	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	N	-1.374(TCAP)
42	37	D/N	rs759317260	0.4139	gnomAD-4.0.0	51	None	0.1841	0.2211	25.6	N	0.291	1.02	0.032417	-0.431	0.1986	-0.7602	0.457538867752	None	0.999125	0.808	0.389126455913	1.0	0.68532627821	-3.09	0.429	0.629	0.119	None	None	1.85874E-06	1.33469E-05	0	0	0	None	0	0	1.85874E-06	0	2.19573E-05	0	None	N	-1.374(TCAP)
43	38	G/C	None	0.3072	gnomAD-4.0.0	52	None	0.7821	0.8285	24.7	D	None	0.45	0.121837	-0.927	0.5612	0.4674	0.478569009243	None	0.999968	0.936	0.899237815192	1.0	0.709348201752	-5.75	0.666	0.699	0.002	None	None	2.40064E-06	0	0	0	0	None	0	0	2.40064E-06	2.625E-06	0	0	None	N	-0.158(TCAP)
44	39	Q/L	rs867308852	0.4576	gnomAD-2.1.1	55	None	0.2207	0.1873	25.0	N	0.433	-0.36	0.060273	0.244	0.3932	-0.2164	0.44834105286	None	0.998256	0.559	0.65458738856	0.99	0.552235364914	-4.44	0.591	0.472	0.007	None	None	2.79E-05	0	0	0	3.81679E-04	None	0	None	2.79E-05	0	0	0	None	N	-0.026(TCAP)
44	39	Q/L	rs867308852	0.4576	gnomAD-3.1.2	55	None	0.2207	0.1873	25.0	N	0.433	-0.36	0.060273	0.244	0.3932	-0.2164	0.44834105286	None	0.998256	0.559	0.65458738856	0.99	0.552235364914	-4.44	0.591	0.472	0.007	None	None	6.57E-06	0	0	0	1.9253E-04	None	0	0	6.57E-06	0	0	0	None	N	-0.026(TCAP)
44	39	Q/L	rs867308852	0.4576	gnomAD-4.0.0	55	None	0.2207	0.1873	25.0	N	0.433	-0.36	0.060273	0.244	0.3932	-0.2164	0.44834105286	None	0.998256	0.559	0.65458738856	0.99	0.552235364914	-4.44	0.591	0.472	0.007	None	None	5.57617E-06	0	0	0	1.78301E-04	None	0	0	5.57617E-06	0	0	1.60031E-05	None	N	-0.026(TCAP)
44	39	Q/R	rs867308852	0.4576	gnomAD-3.1.2	55	None	0.1366	0.1767	24.5	N	None	-0.32	0.028454	0.162	0.3932	-0.1886	0.46916660734	None	0.97525	0.5	0.283371740733	0.985	0.599966287613	-2.52	0.438	0.481	0.039	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	N	-0.404(TCAP)
44	39	Q/R	rs867308852	0.4576	gnomAD-4.0.0	55	None	0.1366	0.1767	24.5	N	None	-0.32	0.028454	0.162	0.3932	-0.1886	0.46916660734	None	0.97525	0.5	0.283371740733	0.985	0.599966287613	-2.52	0.438	0.481	0.039	None	None	2.4783E-06	1.33479E-05	0	0	0	None	0	0	2.4783E-06	2.54234E-06	0	0	None	N	-0.404(TCAP)
45	40	V/L	rs142028110	0.3429	gnomAD-2.1.1	56	None	0.1763	0.1525	22.1	N	-0.047	-0.22	0.060411	-0.306	0.183	-0.8405	0.0842505692678	None	0.999404	0.306	0.417460480802	0.002	0.400479227304	-1.84	0.202	0.529	0.261	None	None	2.83E-05	2.80336E-04	2.82E-05	0	0	None	0	None	2.83E-05	0	0	0	None	N	-0.635(TCAP)
45	40	V/L	rs142028110	0.3429	gnomAD-3.1.2	56	None	0.1763	0.1525	22.1	N	-0.047	-0.22	0.060411	-0.306	0.183	-0.8405	0.0842505692678	None	0.999404	0.306	0.417460480802	0.002	0.400479227304	-1.84	0.202	0.529	0.261	None	None	4.6E-05	1.68952E-04	0	0	0	None	0	0	4.6E-05	0	0	0	None	N	-0.635(TCAP)
45	40	V/L	rs142028110	0.3429	gnomAD-4.0.0	56	None	0.1763	0.1525	22.1	N	-0.047	-0.22	0.060411	-0.306	0.183	-0.8405	0.0842505692678	None	0.999404	0.306	0.417460480802	0.002	0.400479227304	-1.84	0.202	0.529	0.261	None	None	6.84074E-07	0	0	0	0	None	0	0	6.84074E-07	8.99295E-07	0	0	None	N	-0.635(TCAP)
45	40	V/M	None	0.3429	gnomAD-4.0.0	56	None	0.1428	0.168	22.5	N	None	-0.25	0.033024	-0.373	0.3391	-0.3747	0.196944488583	None	0.999469	0.307	0.517377062552	0.404	0.421187460423	-1.82	0.197	0.544	0.083	None	None	6.84074E-07	0	0	0	0	None	0	0	6.84074E-07	8.99295E-07	0	0	None	N	-0.362(TCAP)
48	43	T/A	None	0.5006	gnomAD-4.0.0	70	None	0.0802	0.1122	20.7	N	None	-0.21	0.008503	-0.484	0.1177	-0.9777	0.0817590803949	None	0.99914	0.372	0.0954503805726	None	0.335310399532	-1.66	0.13	0.091	0.923	None	None	2.73628E-06	2.98686E-05	0	0	0	None	0	0	2.73628E-06	1.79858E-06	0	1.65579E-05	None	N	0.043(TCAP)
48	43	T/I	rs1295047971	0.5006	gnomAD-2.1.1	70	None	0.2762	0.4465	22.4	N	-0.176	-0.29	0.033704	-0.254	0.2174	-0.581	0.0969335790404	None	0.629599	0.582	0.442363741745	0.128	0.432298749685	-2.77	0.311	0.278	0.092	None	None	3.98E-06	0	0	0	5.45E-05	None	0	None	3.98E-06	0	0	0	None	N	-0.067(TCAP)
48	43	T/I	rs1295047971	0.5006	gnomAD-4.0.0	70	None	0.2762	0.4465	22.4	N	-0.176	-0.29	0.033704	-0.254	0.2174	-0.581	0.0969335790404	None	0.629599	0.582	0.442363741745	0.128	0.432298749685	-2.77	0.311	0.278	0.092	None	None	1.20032E-06	0	0	0	2.75482E-04	None	0	0	1.20032E-06	0	0	0	None	N	-0.067(TCAP)
48	43	T/P	None	0.5006	gnomAD-4.0.0	70	None	0.0927	0.1328	21.3	N	None	-0.22	0.008748	-0.303	0.1015	-0.9995	0.109768839861	None	0.99562	0.549	0.183819452728	None	0.342520654202	-2.91	0.256	0.154	0.355	None	None	6.84069E-07	0	0	0	2.52029E-05	None	0	0	6.84069E-07	0	0	0	None	N	-0.021(TCAP)
49	44	S/F	rs368887734	0.6573	gnomAD-2.1.1	73	None	0.3917	0.5475	None	D	-0.913	None	None	-0.999	None	None	None	None	None	None	None	0.926	None	None	0.442	0.442	None	None	None	3.98E-06	0	0	0	0	None	0	None	3.98E-06	0	8.8E-06	0	None	N	0.177(TCAP)
49	44	S/F	rs368887734	0.6573	gnomAD-3.1.2	73	None	0.3917	0.5475	None	D	-0.913	None	None	-0.999	None	None	None	None	None	None	None	0.926	None	None	0.442	0.442	None	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	0.177(TCAP)
49	44	S/F	rs368887734	0.6573	gnomAD-4.0.0	73	None	0.3917	0.5475	None	D	-0.913	None	None	-0.999	None	None	None	None	None	None	None	0.926	None	None	0.442	0.442	None	None	None	6.57004E-06	0	0	0	0	None	0	0	6.57004E-06	1.46985E-05	0	0	None	N	0.177(TCAP)
49	44	S/P	rs531066665	0.6573	gnomAD-2.1.1	73	None	0.5153	0.6282	None	D	-0.478	None	None	-0.241	None	None	None	None	None	None	None	0.489	None	None	0.19	0.347	None	None	None	1.19E-05	6.15E-05	0	0	0	None	0	None	1.19E-05	0	1.76E-05	0	None	N	0.001(TCAP)
49	44	S/P	rs531066665	0.6573	gnomAD-3.1.2	73	None	0.5153	0.6282	None	D	-0.478	None	None	-0.241	None	None	None	None	None	None	None	0.489	None	None	0.19	0.347	None	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	0.001(TCAP)
49	44	S/P	rs531066665	0.6573	1000 genomes	73	None	0.5153	0.6282	None	D	-0.478	None	None	-0.241	None	None	None	None	None	None	None	0.489	None	None	0.19	0.347	None	None	None	1.99681E-04	0	0	None	0	1E-03	None	None	1.99681E-04	None	0	None	None	N	0.001(TCAP)
49	44	S/P	rs531066665	0.6573	gnomAD-4.0.0	73	None	0.5153	0.6282	None	D	-0.478	None	None	-0.241	None	None	None	None	None	None	None	0.489	None	None	0.19	0.347	None	None	None	3.40742E-05	3.99808E-05	0	0	0	None	0	0	3.40742E-05	4.40676E-05	0	0	None	N	0.001(TCAP)
49	44	S/Y	rs368887734	0.6573	gnomAD-3.1.2	73	None	0.3626	0.4987	26.5	D	None	0.74	0.050263	-0.763	0.3548	-0.2018	0.33970494799	None	0.999033	0.5	0.616854986462	0.975	0.544646918774	-3.28	0.44	0.434	0.032	None	None	1.97E-05	7.24E-05	0	0	0	None	0	0	1.97E-05	0	0	0	None	N	0.422(TCAP)
49	44	S/Y	rs368887734	0.6573	gnomAD-4.0.0	73	None	0.3626	0.4987	26.5	D	None	0.74	0.050263	-0.763	0.3548	-0.2018	0.33970494799	None	0.999033	0.5	0.616854986462	0.975	0.544646918774	-3.28	0.44	0.434	0.032	None	None	5.12205E-06	6.76293E-05	0	0	0	None	0	0	5.12205E-06	0	0	0	None	N	0.422(TCAP)
50	45	T/P	rs1217255349	0.3495	gnomAD-2.1.1	102	None	0.2174	0.3041	22.0	N	-0.272	0.17	0.072686	-0.349	0.1719	-0.7277	0.248921944762	None	0.607028	0.459	0.299086750705	0.523	0.402840405703	-3.11	0.133	0.295	0.105	None	None	3.19E-05	1.15207E-04	0	0	0	None	0	None	3.19E-05	0	0	0	None	N	0.057(TCAP)
50	45	T/P	rs1217255349	0.3495	gnomAD-3.1.2	102	None	0.2174	0.3041	22.0	N	-0.272	0.17	0.072686	-0.349	0.1719	-0.7277	0.248921944762	None	0.607028	0.459	0.299086750705	0.523	0.402840405703	-3.11	0.133	0.295	0.105	None	None	1.32E-05	4.84E-05	0	0	0	None	0	0	1.32E-05	0	0	0	None	N	0.057(TCAP)
50	45	T/P	rs1217255349	0.3495	gnomAD-4.0.0	102	None	0.2174	0.3041	22.0	N	-0.272	0.17	0.072686	-0.349	0.1719	-0.7277	0.248921944762	None	0.607028	0.459	0.299086750705	0.523	0.402840405703	-3.11	0.133	0.295	0.105	None	None	1.31744E-05	4.84097E-05	0	0	0	None	0	0	1.31744E-05	0	0	0	None	N	0.057(TCAP)
50	45	T/S	None	0.3495	gnomAD-4.0.0	102	None	0.1036	0.1206	22.8	N	None	0.25	0.059708	-0.446	0.106	-0.8764	0.0756264625943	None	0.616553	0.267	0.124217242631	None	0.409987330437	-1.69	0.07	0.26	0.64	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	-0.183(TCAP)
51	46	L/R	rs868419744	0.1521	gnomAD-2.1.1	103	None	0.4515	0.6759	25.6	N	-1.321	-0.19	0.081349	-0.77	0.2315	-0.3064	0.559304083359	None	0.86415	0.648	0.798374310559	1.0	0.676930069923	-3.73	0.6	0.687	0.188	None	None	7.07E-06	8.01E-05	0	0	0	None	0	None	7.07E-06	0	0	0	None	N	-0.898(TCAP)
51	46	L/R	rs868419744	0.1521	gnomAD-3.1.2	103	None	0.4515	0.6759	25.6	N	-1.321	-0.19	0.081349	-0.77	0.2315	-0.3064	0.559304083359	None	0.86415	0.648	0.798374310559	1.0	0.676930069923	-3.73	0.6	0.687	0.188	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	N	-0.898(TCAP)
51	46	L/R	rs868419744	0.1521	gnomAD-4.0.0	103	None	0.4515	0.6759	25.6	N	-1.321	-0.19	0.081349	-0.77	0.2315	-0.3064	0.559304083359	None	0.86415	0.648	0.798374310559	1.0	0.676930069923	-3.73	0.6	0.687	0.188	None	None	3.09775E-06	5.33718E-05	0	0	0	None	0	0	3.09775E-06	0	0	1.60036E-05	None	N	-0.898(TCAP)
51	46	L/V	None	0.1521	gnomAD-4.0.0	103	None	0.1323	0.1934	23.2	N	None	-0.23	0.017893	-1.14	0.3768	-0.478	0.465082784396	None	0.906761	0.541	0.574195325796	0.996	0.571876585484	-1.87	0.369	0.505	0.057	None	None	6.84068E-07	0	0	0	0	None	0	0	6.84068E-07	8.99292E-07	0	0	None	N	-0.693(TCAP)
52	47	P/R	rs761625399	0.5442	gnomAD-2.1.1	111	None	0.252	0.4032	25.6	N	0.137	0.99	0.035467	0.135	0.2194	-0.7324	0.476885664701	None	0.999668	0.622	0.318828661733	1.0	0.667733848095	-5.6	0.537	0.751	0.028	None	None	7.96E-06	0	0	0	0	None	0	None	7.96E-06	0	1.76E-05	0	None	N	-0.317(TCAP)
52	47	P/R	rs761625399	0.5442	gnomAD-4.0.0	111	None	0.252	0.4032	25.6	N	0.137	0.99	0.035467	0.135	0.2194	-0.7324	0.476885664701	None	0.999668	0.622	0.318828661733	1.0	0.667733848095	-5.6	0.537	0.751	0.028	None	None	2.73627E-06	0	0	0	0	None	0	0	2.73627E-06	3.59717E-06	0	0	None	N	-0.317(TCAP)
53	48	G/S	rs150902810	0.3300	gnomAD-2.1.1	115	None	0.1122	0.1603	None	N	-1.021	None	None	-0.944	None	None	None	None	None	None	None	1.0	None	None	0.392	0.729	None	None	None	3.18E-05	6.15E-05	5.78E-05	0	5.45E-05	None	0	None	3.18E-05	0	3.52E-05	0	None	N	0.231(TCAP)
53	48	G/S	rs150902810	0.3300	gnomAD-3.1.2	115	None	0.1122	0.1603	None	N	-1.021	None	None	-0.944	None	None	None	None	None	None	None	1.0	None	None	0.392	0.729	None	None	None	1.31E-05	2.41E-05	0	0	0	None	0	0	1.31E-05	1.47E-05	0	0	None	N	0.231(TCAP)
53	48	G/S	rs150902810	0.3300	1000 genomes	115	None	0.1122	0.1603	None	N	-1.021	None	None	-0.944	None	None	None	None	None	None	None	1.0	None	None	0.392	0.729	None	None	None	1.99681E-04	8E-04	0	None	0	0	None	None	1.99681E-04	None	0	None	None	N	0.231(TCAP)
53	48	G/S	rs150902810	0.3300	gnomAD-4.0.0	115	None	0.1122	0.1603	None	N	-1.021	None	None	-0.944	None	None	None	None	None	None	None	1.0	None	None	0.392	0.729	None	None	None	7.43445E-06	1.3328E-05	3.33222E-05	0	0	None	0	0	7.43445E-06	2.54236E-06	3.29395E-05	4.79969E-05	None	N	0.231(TCAP)
53	48	G/V	None	0.3300	gnomAD-4.0.0	115	None	0.4069	0.6411	23.9	N	None	0.99	0.047517	-0.427	0.1671	-0.7572	0.518063289252	None	1.0	0.453	0.443999229985	1.0	0.645851373672	-5.65	0.486	0.804	0.004	None	None	3.42034E-06	0	0	0	0	None	0	0	3.42034E-06	3.59717E-06	0	1.65579E-05	None	N	-0.001(TCAP)
54	49	V/L	None	0.1610	gnomAD-4.0.0	121	None	0.354	0.5092	22.4	N	None	-0.26	0.027673	-0.649	0.2053	-0.7688	0.0908555217513	None	0.878887	0.571	0.378322506985	0.094	0.526414990425	-1.79	0.26	0.469	0.689	None	None	4.10442E-06	0	0	0	0	None	0	0	4.10442E-06	5.39576E-06	0	0	None	N	-1.127(TCAP)
54	49	V/M	rs139517732	0.1610	gnomAD-2.1.1	121	None	0.2615	0.3965	None	N	-0.932	None	None	-0.676	None	None	None	None	None	None	None	0.662	None	None	0.39	0.517	None	None	None	4.25E-05	0	2.82E-05	0	5.52597E-04	None	0	None	4.25E-05	0	0	0	None	N	-1.137(TCAP)
54	49	V/M	rs139517732	0.1610	gnomAD-3.1.2	121	None	0.2615	0.3965	None	N	-0.932	None	None	-0.676	None	None	None	None	None	None	None	0.662	None	None	0.39	0.517	None	None	None	3.94E-05	0	6.54E-05	0	9.63391E-04	None	0	0	3.94E-05	0	0	0	None	N	-1.137(TCAP)
54	49	V/M	rs139517732	0.1610	1000 genomes	121	None	0.2615	0.3965	None	N	-0.932	None	None	-0.676	None	None	None	None	None	None	None	0.662	None	None	0.39	0.517	None	None	None	5.99042E-04	0	0	None	3E-03	0	None	None	5.99042E-04	None	0	None	None	N	-1.137(TCAP)
54	49	V/M	rs139517732	0.1610	http://www.ncbi.nlm.nih.gov/pubmed/11846417; http://www.ncbi.nlm.nih.gov/pubmed/27125723;	121	DCM;	0.2615	0.3965	None	N	-0.932	None	None	-0.676	None	None	None	None	None	None	None	0.662	None	None	0.39	0.517	None	het	Genetic analysis of JP DCM families, unknown penetrance; decreases binding of TTN to TCAP (Y2H assay); Variant prioritisation; filtering with pathogenicity/stability tools; MD analysis of binding of TTN to TCAP	None	None	None	None	None	None	None	None	None	None	None	None	None	N	-1.137(TCAP)
54	49	V/M	rs139517732	0.1610	gnomAD-4.0.0	121	None	0.2615	0.3965	None	N	-0.932	None	None	-0.676	None	None	None	None	None	None	None	0.662	None	None	0.39	0.517	None	None	None	3.71722E-05	1.33284E-05	3.33178E-05	0	1.11458E-03	None	0	1.65017E-04	3.71722E-05	3.38981E-06	0	3.19969E-05	None	N	-1.137(TCAP)
55	50	Q/H	rs1561527314	0.6650	gnomAD-4.0.0	122	None	0.2926	0.3187	23.8	N	None	-0.31	0.029356	-0.427	0.4002	-0.2451	0.330562522634	None	0.999308	0.483	0.400468435593	0.995	0.686766564846	-3.14	0.49	0.586	0.112	None	None	2.40064E-06	0	0	0	0	None	0	0	2.40064E-06	2.625E-06	0	0	None	N	0.073(TCAP)
55	50	Q/R	None	0.6650	gnomAD-4.0.0	122	None	0.1502	0.1661	26.1	N	None	-0.21	0.020723	-0.005	0.2656	-0.3892	0.217110985681	None	0.97775	0.42	0.190952846119	0.868	0.690572619438	-2.52	0.502	0.555	0.837	None	None	1.5905E-06	0	0	0	0	None	0	0	1.5905E-06	2.85649E-06	0	0	None	N	-0.47(TCAP)
56	51	I/L	rs2094107740	0.3005	gnomAD-3.1.2	123	None	0.24	0.2788	23.1	N	None	-0.29	0.035663	-0.589	0.3678	-0.0113	0.180988953269	None	0.655564	0.659	0.479893544335	0.368	0.752667367458	-1.28	0.387	0.325	0.13	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	-0.624(TCAP)
56	51	I/L	rs2094107740	0.3005	gnomAD-4.0.0	123	None	0.24	0.2788	23.1	N	None	-0.29	0.035663	-0.589	0.3678	-0.0113	0.180988953269	None	0.655564	0.659	0.479893544335	0.368	0.752667367458	-1.28	0.387	0.325	0.13	None	None	6.57497E-06	0	0	0	0	None	0	0	6.57497E-06	1.47007E-05	0	0	None	N	-0.624(TCAP)
57	52	S/F	rs1274297049	0.3546	gnomAD-3.1.2	125	None	0.2153	0.2199	25.9	N	None	-0.35	0.020145	-0.808	0.4188	-0.2044	0.484009558371	None	0.999803	0.553	0.799950227238	1.0	0.653740167618	-3.83	0.621	0.789	0.306	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	0.153(TCAP)
57	52	S/F	rs1274297049	0.3546	gnomAD-4.0.0	125	None	0.2153	0.2199	25.9	N	None	-0.35	0.020145	-0.808	0.4188	-0.2044	0.484009558371	None	0.999803	0.553	0.799950227238	1.0	0.653740167618	-3.83	0.621	0.789	0.306	None	None	2.56112E-06	0	0	0	0	None	0	0	2.56112E-06	2.39167E-06	0	2.84188E-05	None	N	0.153(TCAP)
58	53	F/L	None	0.2430	gnomAD-4.0.0	127	None	0.9811	0.9682	23.1	N	None	-0.23	0.020351	-0.803	0.2067	-0.6028	0.10116999019	None	0.826107	0.671	0.317084106153	0.009	0.714150965214	-3.73	0.324	0.352	0.35	None	None	1.5905E-06	0	0	0	0	None	1.88168E-05	0	1.5905E-06	0	0	0	None	N	-1.228(TCAP)
59	54	S/R	rs191057824	0.3670	gnomAD-2.1.1	130	None	0.438	0.4388	24.0	N	0.249	-0.26	0.027627	-0.11	0.3155	-0.4018	0.489826376215	None	0.980083	0.522	0.460795861206	1.0	0.683672428131	-3.19	0.528	0.649	0.016	None	None	5.31E-05	4.01E-05	5.64E-05	0	0	None	0	None	5.31E-05	0	9.3E-05	0	None	N	-0.455(TCAP)
59	54	S/R	rs191057824	0.3670	gnomAD-3.1.2	130	None	0.438	0.4388	24.0	N	0.249	-0.26	0.027627	-0.11	0.3155	-0.4018	0.489826376215	None	0.980083	0.522	0.460795861206	1.0	0.683672428131	-3.19	0.528	0.649	0.016	None	None	5.26E-05	7.24E-05	6.54E-05	0	0	None	0	0	5.26E-05	5.88E-05	0	0	None	N	-0.455(TCAP)
59	54	S/R	rs191057824	0.3670	gnomAD-4.0.0	130	None	0.438	0.4388	24.0	N	0.249	-0.26	0.027627	-0.11	0.3155	-0.4018	0.489826376215	None	0.980083	0.522	0.460795861206	1.0	0.683672428131	-3.19	0.528	0.649	0.016	None	None	8.86006E-05	4.00513E-05	8.33278E-05	0	0	None	0	0	8.86006E-05	1.09321E-04	0	9.60215E-05	None	N	-0.455(TCAP)
60	55	D/E	None	0.7091	gnomAD-4.0.0	131	None	0.2253	0.2322	22.8	N	None	0.99	0.010621	-0.327	0.0916	-0.9952	0.0781518737448	None	0.980838	0.543	0.132336055621	None	0.633429944515	-2.51	0.087	0.266	0.03	None	None	2.05221E-06	0	0	0	0	None	0	0	2.05221E-06	2.69788E-06	0	0	None	N	0.089(TCAP)
60	55	D/N	rs35683768	0.7091	gnomAD-2.1.1	131	None	0.1088	0.1043	22.5	N	0.317	0.97	0.037942	0.06	0.127	-0.8005	0.0961291299293	None	0.564601	0.486	0.12205267543	0.308	0.654822587967	-3.17	0.18	0.443	0.127	None	None	1.59E-05	0	0	0	5.45E-05	None	0	None	1.59E-05	0	2.64E-05	0	None	N	-1.221(TCAP)
60	55	D/N	rs35683768	0.7091	gnomAD-3.1.2	131	None	0.1088	0.1043	22.5	N	0.317	0.97	0.037942	0.06	0.127	-0.8005	0.0961291299293	None	0.564601	0.486	0.12205267543	0.308	0.654822587967	-3.17	0.18	0.443	0.127	None	None	6.57E-06	2.42E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	N	-1.221(TCAP)
60	55	D/N	rs35683768	0.7091	gnomAD-4.0.0	131	None	0.1088	0.1043	22.5	N	0.317	0.97	0.037942	0.06	0.127	-0.8005	0.0961291299293	None	0.564601	0.486	0.12205267543	0.308	0.654822587967	-3.17	0.18	0.443	0.127	None	None	1.17724E-05	4.00684E-05	0	0	2.22876E-05	None	0	0	1.17724E-05	1.01694E-05	2.19592E-05	1.60036E-05	None	N	-1.221(TCAP)
60	55	D/V	rs754533155	0.7091	gnomAD-2.1.1	131	None	0.5969	0.5396	24.2	D	0.36	0.87	0.055425	0.132	0.2479	-0.5601	0.227835282734	None	0.999904	0.663	0.451118754121	0.281	0.599928379059	-5.65	0.356	0.526	0.001	None	None	3.98E-06	0	0	0	0	None	0	None	3.98E-06	0	8.8E-06	0	None	N	0.313(TCAP)
60	55	D/V	rs754533155	0.7091	gnomAD-4.0.0	131	None	0.5969	0.5396	24.2	D	0.36	0.87	0.055425	0.132	0.2479	-0.5601	0.227835282734	None	0.999904	0.663	0.451118754121	0.281	0.599928379059	-5.65	0.356	0.526	0.001	None	None	1.59052E-06	0	0	0	0	None	0	0	1.59052E-06	2.85649E-06	0	0	None	N	0.313(TCAP)
60	55	D/Y	rs35683768	0.7091	gnomAD-2.1.1	131	None	0.5253	0.4045	None	N	0.073	None	None	0.188	None	None	None	None	None	None	None	0.992	None	None	0.344	0.511	None	None	None	1.46299E-02	6.98038E-02	1.13438E-02	4.82532E-03	9.04068E-03	None	1.36203E-02	None	1.46299E-02	1.73553E-02	6.38423E-03	1.16311E-02	None	N	0.118(TCAP)
60	55	D/Y	rs35683768	0.7091	gnomAD-3.1.2	131	None	0.5253	0.4045	None	N	0.073	None	None	0.188	None	None	None	None	None	None	None	0.992	None	None	0.344	0.511	None	None	None	2.60441E-02	6.73579E-02	2.57165E-02	4.89631E-03	1.04126E-02	None	1.82007E-02	6.32911E-03	2.60441E-02	5.85053E-03	1.34799E-02	2.48566E-02	None	N	0.118(TCAP)
60	55	D/Y	rs35683768	0.7091	1000 genomes	131	None	0.5253	0.4045	None	N	0.073	None	None	0.188	None	None	None	None	None	None	None	0.992	None	None	0.344	0.511	None	None	None	2.89537E-02	7.19E-02	2.02E-02	None	1.59E-02	8.9E-03	None	None	2.89537E-02	None	1.12E-02	None	None	N	0.118(TCAP)
60	55	D/Y	rs35683768	0.7091	gnomAD-4.0.0	131	None	0.5253	0.4045	None	N	0.073	None	None	0.188	None	None	None	None	None	None	None	0.992	None	None	0.344	0.511	None	None	None	1.03547E-02	6.77265E-02	1.55599E-02	4.86355E-03	4.9271E-03	None	1.60565E-02	1.78277E-02	1.03547E-02	6.06439E-03	1.39886E-02	1.23184E-02	None	N	0.118(TCAP)
62	57	R/C	rs766108359	0.3101	gnomAD-2.1.1	135	None	0.2379	0.2641	28.3	D	-0.905	-0.34	0.030654	-0.546	0.4813	-0.0645	0.537264092094	None	1.0	0.524	0.789176987369	1.0	0.608490347862	-5.11	0.561	0.741	0.152	None	None	1.19E-05	0	0	0	0	None	0	None	1.19E-05	0	2.64E-05	0	None	N	-0.054(TCAP)
62	57	R/C	rs766108359	0.3101	gnomAD-4.0.0	135	None	0.2379	0.2641	28.3	D	-0.905	-0.34	0.030654	-0.546	0.4813	-0.0645	0.537264092094	None	1.0	0.524	0.789176987369	1.0	0.608490347862	-5.11	0.561	0.741	0.152	None	None	4.10443E-06	0	0	3.82614E-05	0	None	0	0	4.10443E-06	2.69789E-06	2.31863E-05	0	None	N	-0.054(TCAP)
62	57	R/G	None	0.3101	gnomAD-4.0.0	135	None	0.3654	0.3801	26.6	N	None	-0.3	0.036771	-1.061	0.3491	-0.2773	0.523221014711	None	0.999854	0.533	0.690662525078	1.0	0.53359246254	-4.47	0.621	0.69	0.29	None	None	6.84071E-07	0	0	0	0	None	0	0	6.84071E-07	8.99295E-07	0	0	None	N	-0.371(TCAP)
62	57	R/H	rs758169489	0.3101	gnomAD-2.1.1	135	None	0.0838	0.0896	None	N	-1.574	None	None	-1.453	None	None	None	None	None	None	None	1.0	None	None	0.499	0.748	None	None	None	7.78E-05	4.01E-05	0	0	8.53328E-04	None	9.8E-05	None	7.78E-05	0	7.75E-06	0	None	N	0.037(TCAP)
62	57	R/H	rs758169489	0.3101	gnomAD-3.1.2	135	None	0.0838	0.0896	None	N	-1.574	None	None	-1.453	None	None	None	None	None	None	None	1.0	None	None	0.499	0.748	None	None	None	3.95E-05	4.83E-05	0	0	3.86698E-04	None	0	0	3.95E-05	2.94E-05	0	0	None	N	0.037(TCAP)
62	57	R/H	rs758169489	0.3101	gnomAD-4.0.0	135	None	0.0838	0.0896	None	N	-1.574	None	None	-1.453	None	None	None	None	None	None	None	1.0	None	None	0.499	0.748	None	None	None	1.85888E-05	2.67173E-05	0	0	3.1211E-04	None	0	0	1.85888E-05	8.47455E-06	3.29366E-05	1.60036E-05	None	N	0.037(TCAP)
63	58	A/T	rs764892312	0.0918	gnomAD-2.1.1	136	None	0.5879	0.5828	None	N	-1.307	None	None	-1.188	None	None	None	None	None	None	None	1.0	None	None	0.393	0.717	None	None	None	3.54E-05	0	0	0	3.51441E-04	None	0	None	3.54E-05	0	2.32E-05	0	None	N	-0.843(TCAP)
63	58	A/T	rs764892312	0.0918	gnomAD-3.1.2	136	None	0.5879	0.5828	None	N	-1.307	None	None	-1.188	None	None	None	None	None	None	None	1.0	None	None	0.393	0.717	None	None	None	1.32E-05	0	6.55E-05	0	0	None	0	0	1.32E-05	1.47E-05	0	0	None	N	-0.843(TCAP)
63	58	A/T	rs764892312	0.0918	gnomAD-4.0.0	136	None	0.5879	0.5828	None	N	-1.307	None	None	-1.188	None	None	None	None	None	None	None	1.0	None	None	0.393	0.717	None	None	None	2.29267E-05	0	5.00133E-05	0	2.00606E-04	None	0	0	2.29267E-05	1.94915E-05	1.09803E-05	1.60046E-05	None	N	-0.843(TCAP)
63	58	A/V	rs761823259	0.0918	gnomAD-2.1.1	136	None	0.543	0.5451	25.4	N	0.548	1.01	0.027785	0.279	0.1792	-0.7655	0.462234641901	None	0.999753	0.59	0.297718772494	1.0	0.580715835094	-2.56	0.399	0.615	0.174	None	None	3.98E-06	0	0	0	0	None	0	None	3.98E-06	4.62E-05	0	0	None	N	-0.787(TCAP)
64	59	K/I	None	0.4257	gnomAD-4.0.0	137	None	0.2331	0.2503	21.7	N	None	-0.31	0.025671	0.064	0.1722	-0.9419	0.1515365786	None	0.999558	0.595	0.20549828249	0.001	0.286356449127	-2.99	0.232	0.515	0.084	None	None	1.59049E-06	0	0	0	0	None	0	0	1.59049E-06	0	0	3.02151E-05	None	N	-0.354(TCAP)
65	60	L/V	None	0.0833	gnomAD-4.0.0	138	None	0.4066	0.4238	22.7	D	None	-0.68	0.022746	-1.147	0.5798	-0.2039	0.463237737213	None	0.998197	0.863	0.449669948863	0.998	0.500668168068	-1.92	0.498	0.679	None	None	None	1.20034E-06	0	0	0	0	None	0	0	1.20034E-06	0	0	3.66354E-05	None	N	-0.757(TCAP)
66	61	T/M	rs372755739	0.2025	gnomAD-2.1.1	139	None	0.0744	0.0718	None	D	-0.086	None	None	-0.03	None	None	None	None	None	None	None	0.014	None	None	0.124	0.383	None	None	None	4.24E-05	0	0	9.65E-05	0	None	9.8E-05	None	4.24E-05	1.19408E-04	3.87E-05	0	None	N	0.005(TCAP)
66	61	T/M	rs372755739	0.2025	gnomAD-3.1.2	139	None	0.0744	0.0718	None	D	-0.086	None	None	-0.03	None	None	None	None	None	None	None	0.014	None	None	0.124	0.383	None	None	None	3.94E-05	0	0	0	0	None	9.42E-05	0	3.94E-05	7.35E-05	0	0	None	N	0.005(TCAP)
66	61	T/M	rs372755739	0.2025	gnomAD-4.0.0	139	None	0.0744	0.0718	None	D	-0.086	None	None	-0.03	None	None	None	None	None	None	None	0.014	None	None	0.124	0.383	None	None	None	4.58489E-05	0	0	3.37769E-05	0	None	1.09327E-04	0	4.58489E-05	4.74569E-05	9.88056E-05	1.60041E-05	None	N	0.005(TCAP)
67	62	I/N	rs952685437	0.1116	gnomAD-3.1.2	140	None	0.9778	0.9777	26.7	D	None	-1.3	0.062771	-2.577	0.8194	0.9574	0.615612516959	None	0.999237	0.808	0.924420087009	1.0	0.626528382301	-4.41	0.879	0.911	None	None	None	1.32E-05	0	0	0	0	None	0	0	1.32E-05	2.94E-05	0	0	None	N	-0.616(TCAP)
67	62	I/N	rs952685437	0.1116	gnomAD-4.0.0	140	None	0.9778	0.9777	26.7	D	None	-1.3	0.062771	-2.577	0.8194	0.9574	0.615612516959	None	0.999237	0.808	0.924420087009	1.0	0.626528382301	-4.41	0.879	0.911	None	None	None	1.31546E-05	0	0	0	0	None	0	0	1.31546E-05	2.94126E-05	0	0	None	N	-0.616(TCAP)
68	63	P/S	rs876658046	0.3781	gnomAD-3.1.2	141	None	0.1723	0.199	22.7	N	None	-0.1	0.020131	-0.829	0.0855	-0.9271	0.0849186609174	None	0.734859	0.469	0.190952846119	0.021	0.47407540679	-4.59	0.193	0.185	0.441	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	N	-0.255(TCAP)
68	63	P/S	rs876658046	0.3781	gnomAD-4.0.0	141	None	0.1723	0.199	22.7	N	None	-0.1	0.020131	-0.829	0.0855	-0.9271	0.0849186609174	None	0.734859	0.469	0.190952846119	0.021	0.47407540679	-4.59	0.193	0.185	0.441	None	None	9.2937E-06	1.33486E-05	0	0	0	None	0	0	9.2937E-06	1.1017E-05	0	1.60046E-05	None	N	-0.255(TCAP)
69	64	A/T	rs1370693255	0.3893	gnomAD-2.1.1	143	None	0.0929	0.0984	22.8	N	-0.419	1.01	0.008245	-0.763	0.0626	-0.967	0.0915661879569	None	0.553945	0.397	0.0986583533028	0.634	0.392634898424	-2.36	0.157	0.293	0.382	None	None	1.77E-05	4.01E-05	0	0	0	None	0	None	1.77E-05	0	3.1E-05	0	None	N	-0.624(TCAP)
69	64	A/T	rs1370693255	0.3893	gnomAD-3.1.2	143	None	0.0929	0.0984	22.8	N	-0.419	1.01	0.008245	-0.763	0.0626	-0.967	0.0915661879569	None	0.553945	0.397	0.0986583533028	0.634	0.392634898424	-2.36	0.157	0.293	0.382	None	None	1.97E-05	4.83E-05	0	0	0	None	0	0	1.97E-05	1.47E-05	0	0	None	N	-0.624(TCAP)
69	64	A/T	rs1370693255	0.3893	gnomAD-4.0.0	143	None	0.0929	0.0984	22.8	N	-0.419	1.01	0.008245	-0.763	0.0626	-0.967	0.0915661879569	None	0.553945	0.397	0.0986583533028	0.634	0.392634898424	-2.36	0.157	0.293	0.382	None	None	1.11525E-05	6.67361E-05	0	0	0	None	0	0	1.11525E-05	1.10169E-05	0	0	None	N	-0.624(TCAP)
70	65	V/A	None	0.0848	gnomAD-4.0.0	144	None	0.4927	0.5132	22.7	N	None	-0.34	0.024941	-1.814	0.2504	-0.4153	0.124059851841	None	0.743557	0.873	0.531389887418	0.11	0.650142729282	-2.56	0.441	0.314	0.179	None	None	1.20036E-06	0	0	0	0	None	0	0	1.20036E-06	1.31255E-06	0	0	None	N	-0.843(TCAP)
70	65	V/M	rs772248060	0.0848	gnomAD-2.1.1	144	None	0.5696	0.6434	24.9	D	-1.227	-0.63	0.037124	-1.155	0.6567	0.5379	0.447034461529	None	0.960972	0.749	0.717771820488	1.0	0.66142475605	-1.92	0.647	0.755	0.006	None	None	4.77E-05	6.15E-05	0	0	0	None	2.28639E-04	None	4.77E-05	0	3.52E-05	0	None	N	-1.404(TCAP)
70	65	V/M	rs772248060	0.0848	gnomAD-3.1.2	144	None	0.5696	0.6434	24.9	D	-1.227	-0.63	0.037124	-1.155	0.6567	0.5379	0.447034461529	None	0.960972	0.749	0.717771820488	1.0	0.66142475605	-1.92	0.647	0.755	0.006	None	None	4.6E-05	2.41E-05	0	0	0	None	0	0	4.6E-05	8.82E-05	0	0	None	N	-1.404(TCAP)
70	65	V/M	rs772248060	0.0848	gnomAD-4.0.0	144	None	0.5696	0.6434	24.9	D	-1.227	-0.63	0.037124	-1.155	0.6567	0.5379	0.447034461529	None	0.960972	0.749	0.717771820488	1.0	0.66142475605	-1.92	0.647	0.755	0.006	None	None	2.41631E-05	2.66909E-05	0	0	0	None	0	0	2.41631E-05	2.11862E-05	1.09789E-04	3.20072E-05	None	N	-1.404(TCAP)
71	66	T/N	None	0.3214	gnomAD-4.0.0	145	None	0.1507	0.1672	25.2	N	None	-0.24	0.018279	-0.283	0.3471	-0.2826	0.374542433298	None	0.981994	0.368	0.432154444652	0.996	0.598912835121	-3.13	0.304	0.721	0.226	None	None	1.20037E-06	0	0	0	0	None	0	0	1.20037E-06	1.31256E-06	0	0	None	N	-0.808(TCAP)
72	67	K/E	None	0.3001	gnomAD-4.0.0	146	None	0.1276	0.1429	21.6	N	None	1.02	0.012401	0.1	0.0691	-1.0164	0.118073783653	None	0.889688	0.561	0.134241683229	None	0.442617714405	-1.72	0.208	0.1	1.0	None	None	2.05223E-06	0	0	0	0	None	0	0	2.05223E-06	0	1.15931E-05	3.3117E-05	None	N	-0.014(TCAP)
72	67	K/T	rs1200039660	0.3001	gnomAD-2.1.1	146	None	0.1224	0.134	23.4	N	-0.19	0.99	0.013364	-0.168	0.0977	-0.9596	0.102262089272	None	0.784552	0.509	0.183819452728	0.006	0.436676204205	-2.83	0.136	0.257	0.61	None	None	3.98E-06	0	0	0	0	None	0	None	3.98E-06	0	8.8E-06	0	None	N	-0.515(TCAP)
73	68	A/G	None	0.4476	gnomAD-4.0.0	148	None	0.1527	0.1847	23.6	N	None	1.01	0.018681	-0.169	0.0999	-0.9425	0.0839709123402	None	0.84903	0.388	0.119812018005	0.001	0.494028091431	-2.26	0.082	0.327	0.34	None	None	6.84057E-07	0	0	0	0	None	0	0	6.84057E-07	8.99292E-07	0	0	None	N	-0.188(TCAP)
74	69	N/K	rs2094104209	0.1960	gnomAD-4.0.0	149	None	0.7122	0.7796	23.0	N	None	-0.3	0.047618	-0.052	0.3162	-0.2018	0.30643641764	None	0.836137	0.674	0.232513804876	0.934	0.448924601078	-3.34	0.387	0.667	0.079	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	0	6.07533E-05	0	None	N	-0.976(TCAP)
74	69	N/S	rs774795341	0.1960	gnomAD-2.1.1	149	None	0.1089	0.1117	22.6	N	-0.96	-0.3	0.047758	-1.003	0.2287	-0.4496	0.105501544212	None	0.881553	0.671	0.216624796971	0.488	0.339877843857	-2.81	0.292	0.642	0.147	None	None	3.98E-06	0	0	0	0	None	0	None	3.98E-06	0	8.8E-06	0	None	N	-0.682(TCAP)
74	69	N/S	rs774795341	0.1960	gnomAD-4.0.0	149	None	0.1089	0.1117	22.6	N	-0.96	-0.3	0.047758	-1.003	0.2287	-0.4496	0.105501544212	None	0.881553	0.671	0.216624796971	0.488	0.339877843857	-2.81	0.292	0.642	0.147	None	None	8.20886E-06	0	0	0	0	None	0	0	8.20886E-06	1.07918E-05	0	0	None	N	-0.682(TCAP)
76	71	G/A	rs138750421	0.1449	gnomAD-2.1.1	152	None	0.494	0.4864	None	D	-0.395	None	None	-0.746	None	None	None	None	None	None	None	1.0	None	None	0.678	0.735	None	None	None	9.9E-05	0	0	0	0	None	0	None	9.9E-05	3.98E-05	1.70374E-04	6.92137E-04	None	N	-0.629(TCAP)
76	71	G/A	rs138750421	0.1449	gnomAD-3.1.2	152	None	0.494	0.4864	None	D	-0.395	None	None	-0.746	None	None	None	None	None	None	None	1.0	None	None	0.678	0.735	None	None	None	1.11723E-04	0	0	2.88018E-04	0	None	3.7679E-04	0	1.11723E-04	1.76377E-04	0	0	None	N	-0.629(TCAP)
76	71	G/A	rs138750421	0.1449	gnomAD-4.0.0	152	None	0.494	0.4864	None	D	-0.395	None	None	-0.746	None	None	None	None	None	None	None	1.0	None	None	0.678	0.735	None	None	None	8.24034E-05	0	0	6.75493E-05	2.22747E-05	None	2.81092E-04	0	8.24034E-05	9.23721E-05	0	4.80138E-05	None	N	-0.629(TCAP)
76	71	G/R	rs771137064	0.1449	gnomAD-4.0.0	152	None	0.9325	0.9377	24.7	D	-0.619	-1.11	0.135489	-1.002	0.7982	0.8815	0.506463245118	None	0.999943	0.889	0.873694922674	1.0	0.696173548698	-5.11	0.823	0.814	0.003	None	None	3.18088E-06	0	0	0	0	None	1.88168E-05	0	3.18088E-06	2.85647E-06	0	0	None	N	-1.835(TCAP)
76	71	G/V	rs138750421	0.1449	gnomAD-2.1.1	152	None	0.9318	0.9369	24.3	D	None	-1.12	0.103511	-0.307	0.7843	0.8309	0.518063289252	None	1.0	0.908	0.927192934444	1.0	0.619113624096	-5.75	0.819	0.808	0.008	None	None	3.98E-06	0	0	9.92E-05	0	None	0	None	3.98E-06	0	0	0	None	N	-1.019(TCAP)
76	71	G/V	rs138750421	0.1449	gnomAD-4.0.0	152	None	0.9318	0.9369	24.3	D	None	-1.12	0.103511	-0.307	0.7843	0.8309	0.518063289252	None	1.0	0.908	0.927192934444	1.0	0.619113624096	-5.75	0.819	0.808	0.008	None	None	6.84065E-07	0	0	3.82614E-05	0	None	0	0	6.84065E-07	0	0	0	None	N	-1.019(TCAP)
77	72	R/Q	rs727503709	0.4558	gnomAD-2.1.1	153	None	0.1135	0.1078	23.0	N	0.097	-0.2	0.024026	-0.486	0.2124	-0.7436	0.287075476058	None	0.706755	0.511	0.232513804876	0.991	0.419379234314	-2.49	0.263	0.665	0.263	None	None	7.96E-06	0	0	0	0	None	0	None	7.96E-06	0	1.76E-05	0	None	N	-0.385(TCAP)
77	72	R/Q	rs727503709	0.4558	gnomAD-4.0.0	153	None	0.1135	0.1078	23.0	N	0.097	-0.2	0.024026	-0.486	0.2124	-0.7436	0.287075476058	None	0.706755	0.511	0.232513804876	0.991	0.419379234314	-2.49	0.263	0.665	0.263	None	None	4.10435E-06	2.98686E-05	0	0	0	None	0	0	4.10435E-06	2.69788E-06	2.31868E-05	0	None	N	-0.385(TCAP)
78	73	Y/H	None	0.0963	gnomAD-4.0.0	154	None	0.9783	0.9767	25.0	D	None	-1.27	0.066891	-1.929	0.7769	0.9321	0.508231719013	None	0.737564	0.864	0.744883404023	0.999	0.589641571045	-3.11	0.657	0.685	None	None	None	1.59044E-06	0	0	0	0	None	0	0	1.59044E-06	0	1.43275E-05	0	None	N	-0.08(TCAP)
79	74	S/F	None	0.1503	gnomAD-4.0.0	155	None	0.2569	0.2611	28.2	N	None	0.96	0.025239	-0.786	0.28	-0.5522	0.471223010281	None	0.998676	0.516	0.519946186488	0.999	0.531730651855	-3.68	0.508	0.759	0.001	None	None	2.73624E-06	0	0	0	0	None	0	6.93722E-04	2.73624E-06	0	0	0	None	N	-0.255(TCAP)
79	74	S/T	rs746487470	0.1503	gnomAD-2.1.1	155	None	0.1057	0.1036	23.5	N	0.247	1.21	0.02129	0.246	0.0375	-1.0506	0.0819297948795	None	0.744396	0.373	0.0716867268079	0.076	0.488727807999	-1.57	0.182	0.479	0.635	None	None	3.98E-06	0	0	0	0	None	3.27E-05	None	3.98E-06	0	0	0	None	N	-0.622(TCAP)
79	74	S/T	rs746487470	0.1503	gnomAD-4.0.0	155	None	0.1057	0.1036	23.5	N	0.247	1.21	0.02129	0.246	0.0375	-1.0506	0.0819297948795	None	0.744396	0.373	0.0716867268079	0.076	0.488727807999	-1.57	0.182	0.479	0.635	None	None	1.59045E-06	0	0	0	0	None	0	0	1.59045E-06	0	1.43275E-05	0	None	N	-0.622(TCAP)
79	74	S/Y	None	0.1503	gnomAD-4.0.0	155	None	0.2652	0.2654	27.2	N	None	0.98	0.027534	-0.476	0.2552	-0.6404	0.516925399128	None	0.99995	0.546	0.487772906946	1.0	0.554801642895	-3.68	0.468	0.759	0.001	None	None	6.8406E-07	0	0	0	0	None	0	0	6.8406E-07	8.9929E-07	0	0	None	N	-0.029(TCAP)
82	77	A/D	None	0.0799	http://www.ncbi.nlm.nih.gov/pubmed/33449170;	158	CFTD;	0.9967	0.9965	26.1	D	None	-1.06	0.170734	-2.797	0.8178	0.947	0.565517819109	None	0.999943	0.834	0.901813502436	1.0	0.732051610947	-3.78	0.783	0.898	None	comp het with R34807Sfs*7 (in trans)	Genetic analysis of TTN in 30 CM patients; comp het with truncating; Protein unfolded; Tm 37 degrees lower than WT	None	None	None	None	None	None	None	None	None	None	None	None	None	N	-1.93(TCAP)
82	77	A/T	rs1575010544	0.0799	gnomAD-3.1.2	158	None	0.8169	0.7815	24.3	D	None	-1.02	0.114113	-1.801	0.7982	0.8815	0.457598942377	None	0.999657	0.784	0.653846678015	1.0	0.663289487362	-2.49	0.784	0.789	None	None	None	6.57E-06	0	0	0	1.92678E-04	None	0	0	6.57E-06	0	0	0	None	N	-1.555(TCAP)
82	77	A/T	rs1575010544	0.0799	gnomAD-4.0.0	158	None	0.8169	0.7815	24.3	D	None	-1.02	0.114113	-1.801	0.7982	0.8815	0.457598942377	None	0.999657	0.784	0.653846678015	1.0	0.663289487362	-2.49	0.784	0.789	None	None	None	3.09756E-06	0	0	0	6.68479E-05	None	0	0	3.09756E-06	0	1.09791E-05	1.59995E-05	None	N	-1.555(TCAP)
84	79	N/D	rs1349693054	0.1299	gnomAD-2.1.1	161	None	0.8687	0.8582	26.8	D	-1.984	0.28	0.103116	-1.371	0.6147	0.7035	0.492487482805	None	0.957591	0.837	0.45553875121	0.999	0.57453328371	-3.19	0.615	0.615	None	None	None	3.98E-06	0	2.89E-05	0	0	None	0	None	3.98E-06	0	0	0	None	N	0.095(TCAP)
84	79	N/D	rs1349693054	0.1299	gnomAD-4.0.0	161	None	0.8687	0.8582	26.8	D	-1.984	0.28	0.103116	-1.371	0.6147	0.7035	0.492487482805	None	0.957591	0.837	0.45553875121	0.999	0.57453328371	-3.19	0.615	0.615	None	None	None	1.59045E-06	0	2.28624E-05	0	0	None	0	0	1.59045E-06	0	0	0	None	N	0.095(TCAP)
84	79	N/K	rs142851233	0.1299	gnomAD-2.1.1	161	None	0.9865	0.9843	23.3	D	0.259	0.25	0.065517	-0.152	0.5633	0.6602	0.496805764145	None	0.557057	0.822	0.301122078929	1.0	0.595495581627	-3.83	0.545	0.726	None	None	None	3.98E-06	0	0	0	0	None	0	None	3.98E-06	0	8.79E-06	0	None	N	-0.504(TCAP)
84	79	N/K	rs142851233	0.1299	gnomAD-3.1.2	161	None	0.9865	0.9843	23.3	D	0.259	0.25	0.065517	-0.152	0.5633	0.6602	0.496805764145	None	0.557057	0.822	0.301122078929	1.0	0.595495581627	-3.83	0.545	0.726	None	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	-0.504(TCAP)
84	79	N/K	rs142851233	0.1299	gnomAD-4.0.0	161	None	0.9865	0.9843	23.3	D	0.259	0.25	0.065517	-0.152	0.5633	0.6602	0.496805764145	None	0.557057	0.822	0.301122078929	1.0	0.595495581627	-3.83	0.545	0.726	None	None	None	6.5722E-06	0	0	0	0	None	0	0	6.5722E-06	1.47007E-05	0	0	None	N	-0.504(TCAP)
84	79	N/S	rs912344670	0.1299	gnomAD-3.1.2	161	None	0.3145	0.289	24.2	D	None	0.32	0.025222	-0.684	0.3939	-0.1293	0.415421845615	None	0.956537	0.759	0.26169431596	0.999	0.470971405506	-3.19	0.488	0.583	None	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	-0.098(TCAP)
84	79	N/S	rs912344670	0.1299	gnomAD-4.0.0	161	None	0.3145	0.289	24.2	D	None	0.32	0.025222	-0.684	0.3939	-0.1293	0.415421845615	None	0.956537	0.759	0.26169431596	0.999	0.470971405506	-3.19	0.488	0.583	None	None	None	2.47828E-06	0	0	0	0	None	0	0	2.47828E-06	3.38981E-06	0	0	None	N	-0.098(TCAP)
85	80	G/E	rs758092470	0.4452	gnomAD-2.1.1	162	None	0.3117	0.2101	25.5	N	-0.351	-0.07	0.035816	-0.775	0.2184	-0.3075	0.526218639335	None	0.99968	0.394	0.442261297928	1.0	0.622150301933	-4.93	0.468	0.679	0.567	None	None	3.98E-06	0	0	0	0	None	0	None	3.98E-06	4.62E-05	0	0	None	I	0.476(TCAP)
85	80	G/E	rs758092470	0.4452	gnomAD-4.0.0	162	None	0.3117	0.2101	25.5	N	-0.351	-0.07	0.035816	-0.775	0.2184	-0.3075	0.526218639335	None	0.99968	0.394	0.442261297928	1.0	0.622150301933	-4.93	0.468	0.679	0.567	None	None	1.59047E-06	0	0	0	0	None	1.88168E-05	0	1.59047E-06	0	0	0	None	I	0.476(TCAP)
86	81	S/F	None	0.1127	gnomAD-4.0.0	163	None	0.2923	0.2331	28.0	N	None	-0.22	0.044601	-0.968	0.2685	-0.2405	0.470340502162	None	0.986885	0.49	0.634526825879	1.0	0.57319688797	-3.33	0.5	0.609	0.843	None	None	1.59046E-06	0	0	0	0	None	0	0	1.59046E-06	0	1.43275E-05	0	None	I	-0.769(TCAP)
86	81	S/Y	rs749985986	0.1127	gnomAD-2.1.1	163	None	0.3017	0.2535	None	N	-0.968	None	None	-0.746	None	None	None	None	None	None	None	1.0	None	None	0.463	0.616	None	None	None	3.98E-06	6.15E-05	0	0	0	None	0	None	3.98E-06	0	0	0	None	I	-0.312(TCAP)
86	81	S/Y	rs749985986	0.1127	gnomAD-3.1.2	163	None	0.3017	0.2535	None	N	-0.968	None	None	-0.746	None	None	None	None	None	None	None	1.0	None	None	0.463	0.616	None	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	I	-0.312(TCAP)
86	81	S/Y	rs749985986	0.1127	gnomAD-4.0.0	163	None	0.3017	0.2535	None	N	-0.968	None	None	-0.746	None	None	None	None	None	None	None	1.0	None	None	0.463	0.616	None	None	None	6.57082E-06	2.41313E-05	0	0	0	None	0	0	6.57082E-06	0	0	0	None	I	-0.312(TCAP)
87	82	G/R	rs756996890	0.1019	gnomAD-2.1.1	164	None	0.8602	0.8233	25.3	D	0.001	-0.87	0.055257	-0.27	0.7507	0.77	0.506463245118	None	0.999937	0.863	0.873851217738	1.0	0.730567872524	-5.11	0.819	0.865	None	None	None	7.95E-06	0	0	0	0	None	3.27E-05	None	7.95E-06	0	8.79E-06	0	None	N	-2.239(TCAP)
87	82	G/R	rs756996890	0.1019	gnomAD-4.0.0	164	None	0.8602	0.8233	25.3	D	0.001	-0.87	0.055257	-0.27	0.7507	0.77	0.506463245118	None	0.999937	0.863	0.873851217738	1.0	0.730567872524	-5.11	0.819	0.865	None	None	None	1.36819E-06	0	4.47187E-05	0	0	None	0	0	1.36819E-06	0	0	0	None	N	-2.239(TCAP)
87	82	G/V	None	0.1019	gnomAD-4.0.0	164	None	0.9411	0.9224	24.0	D	None	-0.9	0.055812	-0.423	0.7507	0.77	0.518063289252	None	1.0	0.856	0.931201369921	1.0	0.658523201942	-5.75	0.831	0.837	None	None	None	1.36819E-06	0	0	0	0	None	0	0	1.36819E-06	1.79869E-06	0	0	None	N	-2.076(TCAP)
88	83	Q/E	None	0.3654	gnomAD-4.0.0	165	None	0.0887	0.0837	24.4	N	None	-0.13	0.025436	-0.21	0.1982	-0.3016	0.455994801244	None	0.995572	0.374	0.255777322467	0.978	0.53685605526	-1.87	0.35	0.404	0.954	None	None	1.2004E-06	0	0	0	0	None	0	0	1.2004E-06	1.31259E-06	0	0	None	N	-1.409(TCAP)
89	84	A/G	rs200165636	0.0757	gnomAD-2.1.1	166	None	0.3265	0.2773	None	D	-1.151	None	None	-0.998	None	None	None	None	None	None	None	1.0	None	None	0.514	0.625	None	None	None	1.37894E-04	8.01E-05	0	0	0	None	0	None	1.37894E-04	0	2.7875E-04	1.38389E-04	None	N	-0.196(TCAP)
89	84	A/G	rs200165636	0.0757	gnomAD-3.1.2	166	None	0.3265	0.2773	None	D	-1.151	None	None	-0.998	None	None	None	None	None	None	None	1.0	None	None	0.514	0.625	None	None	None	1.24862E-04	1.44781E-04	6.54E-05	0	0	None	0	0	1.24862E-04	1.61665E-04	0	4.77555E-04	None	N	-0.196(TCAP)
89	84	A/G	rs200165636	0.0757	gnomAD-4.0.0	166	None	0.3265	0.2773	None	D	-1.151	None	None	-0.998	None	None	None	None	None	None	None	1.0	None	None	0.514	0.625	None	None	None	2.16237E-04	1.06778E-04	1.6665E-05	0	0	None	0	0	2.16237E-04	2.82209E-04	0	1.12025E-04	None	N	-0.196(TCAP)
89	84	A/T	rs1259283214	0.0757	gnomAD-4.0.0	166	None	0.1491	0.1285	24.1	N	None	-0.36	0.021901	-0.96	0.4813	-0.0645	0.457598942377	None	0.99967	0.558	0.486135451721	1.0	0.643376111984	-2.56	0.43	0.752	0.143	None	None	1.20039E-06	6.33473E-05	0	0	0	None	0	0	1.20039E-06	0	0	0	None	N	-0.574(TCAP)
89	84	A/V	rs200165636	0.0757	gnomAD-2.1.1	166	None	0.2035	0.1746	25.5	N	-0.061	-0.25	0.014263	-0.415	0.4394	-0.1654	0.462690307121	None	0.999753	0.522	0.619501705969	1.0	0.657118797302	-2.56	0.393	0.707	0.108	None	None	7.95E-06	0	0	0	0	None	6.53E-05	None	7.95E-06	0	0	0	None	N	-0.398(TCAP)
89	84	A/V	rs200165636	0.0757	gnomAD-3.1.2	166	None	0.2035	0.1746	25.5	N	-0.061	-0.25	0.014263	-0.415	0.4394	-0.1654	0.462690307121	None	0.999753	0.522	0.619501705969	1.0	0.657118797302	-2.56	0.393	0.707	0.108	None	None	1.97E-05	2.41E-05	0	0	0	None	0	0	1.97E-05	2.94E-05	0	0	None	N	-0.398(TCAP)
89	84	A/V	rs200165636	0.0757	gnomAD-4.0.0	166	None	0.2035	0.1746	25.5	N	-0.061	-0.25	0.014263	-0.415	0.4394	-0.1654	0.462690307121	None	0.999753	0.522	0.619501705969	1.0	0.657118797302	-2.56	0.393	0.707	0.108	None	None	8.05467E-06	1.33472E-05	0	0	0	None	0	0	8.05467E-06	5.93232E-06	5.48968E-05	0	None	N	-0.398(TCAP)
90	85	T/A	None	0.2123	gnomAD-4.0.0	168	None	0.1288	0.1154	23.3	N	None	-0.4	0.016509	-0.663	0.4444	-0.0797	0.451143628614	None	0.987681	0.344	0.422040124859	0.994	0.500570893288	-3.11	0.432	0.544	0.041	None	None	1.59048E-06	0	0	0	0	None	0	0	1.59048E-06	2.85651E-06	0	0	None	N	-0.589(TCAP)
91	86	S/I	rs1367815458	0.0588	gnomAD-3.1.2	169	None	0.7851	0.7674	25.6	D	None	-0.32	0.031102	-0.123	0.5444	0.1338	0.503214603424	None	0.999428	0.56	0.795195521471	1.0	0.689429342747	-3.83	0.517	0.881	0.055	None	None	6.57E-06	0	0	0	1.92308E-04	None	0	0	6.57E-06	0	0	0	None	N	-0.83(TCAP)
91	86	S/I	rs1367815458	0.0588	gnomAD-4.0.0	169	None	0.7851	0.7674	25.6	D	None	-0.32	0.031102	-0.123	0.5444	0.1338	0.503214603424	None	0.999428	0.56	0.795195521471	1.0	0.689429342747	-3.83	0.517	0.881	0.055	None	None	6.57186E-06	0	0	0	1.92308E-04	None	0	0	6.57186E-06	0	0	0	None	N	-0.83(TCAP)
91	86	S/N	None	0.0588	gnomAD-4.0.0	169	None	0.6693	0.6519	24.7	D	None	-0.32	0.022306	-0.344	0.5621	0.2032	0.445512622103	None	0.995739	0.499	0.364926071151	0.997	0.705870509148	-1.92	0.366	0.682	0.138	None	None	1.20038E-06	0	0	0	0	None	0	0	1.20038E-06	1.31257E-06	0	0	None	N	-1.056(TCAP)
91	86	S/T	None	0.0588	gnomAD-4.0.0	169	None	0.2449	0.1905	24.6	N	None	-0.25	0.01837	-0.403	0.3853	-0.2442	0.439334003021	None	0.994639	0.483	0.273070737957	0.981	0.673511743546	-1.92	0.304	0.599	0.753	None	None	3.60113E-06	1.26695E-04	0	0	0	None	0	0	3.60113E-06	0	0	3.66327E-05	None	N	-1.371(TCAP)
92	87	T/A	rs767442718	0.1489	gnomAD-2.1.1	171	None	0.1219	0.1161	24.3	N	-0.6	-0.28	0.01767	-0.734	0.4166	-0.1518	0.458215186878	None	0.987681	0.339	0.416707687347	0.998	0.57751750946	-3.11	0.415	0.631	0.057	None	None	3.98E-06	0	0	0	0	None	0	None	3.98E-06	0	0	1.6292E-04	None	N	-1.719(TCAP)
92	87	T/A	rs767442718	0.1489	gnomAD-3.1.2	171	None	0.1219	0.1161	24.3	N	-0.6	-0.28	0.01767	-0.734	0.4166	-0.1518	0.458215186878	None	0.987681	0.339	0.416707687347	0.998	0.57751750946	-3.11	0.415	0.631	0.057	None	None	6.57E-06	0	0	0	0	None	9.42E-05	0	6.57E-06	0	0	0	None	N	-1.719(TCAP)
92	87	T/A	rs767442718	0.1489	gnomAD-4.0.0	171	None	0.1219	0.1161	24.3	N	-0.6	-0.28	0.01767	-0.734	0.4166	-0.1518	0.458215186878	None	0.987681	0.339	0.416707687347	0.998	0.57751750946	-3.11	0.415	0.631	0.057	None	None	2.56113E-06	0	0	0	0	None	3.13666E-05	0	2.56113E-06	0	0	0	None	N	-1.719(TCAP)
92	87	T/S	rs767442718	0.1489	gnomAD-2.1.1	171	None	0.1497	0.139	24.4	N	-0.244	-0.2	0.023224	-0.649	0.2408	-0.3387	0.440747610594	None	0.993617	0.318	0.358340041657	0.998	0.587843298912	-2.49	0.387	0.603	0.226	None	None	3.98E-06	0	0	0	0	None	3.27E-05	None	3.98E-06	0	0	0	None	N	-2.022(TCAP)
92	87	T/S	rs767442718	0.1489	gnomAD-4.0.0	171	None	0.1497	0.139	24.4	N	-0.244	-0.2	0.023224	-0.649	0.2408	-0.3387	0.440747610594	None	0.993617	0.318	0.358340041657	0.998	0.587843298912	-2.49	0.387	0.603	0.226	None	None	1.5905E-06	0	0	0	0	None	0	0	1.5905E-06	0	1.43275E-05	0	None	N	-2.022(TCAP)
93	88	A/S	None	0.0659	gnomAD-4.0.0	172	None	0.2517	0.254	24.8	D	None	-0.49	0.028257	-1.436	0.5906	0.2375	0.44573178934	None	0.999317	0.712	0.552166673682	1.0	0.586112141609	-1.92	0.562	0.613	None	None	None	2.05225E-06	0	0	0	0	None	0	0	2.05225E-06	2.69795E-06	0	0	None	N	-1.319(TCAP)
93	88	A/T	rs1575009860	0.0659	gnomAD-4.0.0	172	None	0.3087	0.3166	25.3	D	None	-0.48	0.025184	-1.231	0.57	0.1693	0.457598942377	None	0.99967	0.662	0.57907379108	1.0	0.619070529938	-2.56	0.573	0.73	None	None	None	2.05225E-06	0	0	0	0	None	0	0	2.05225E-06	2.69795E-06	0	0	None	N	-1.535(TCAP)
93	88	A/V	rs1473207810	0.0659	gnomAD-2.1.1	172	None	0.4902	0.507	25.9	D	-0.094	-0.33	0.013725	-0.31	0.5024	-0.0038	0.462690307121	None	0.999769	0.624	0.594056560588	1.0	0.641351819038	-2.56	0.439	0.659	None	None	None	3.98E-06	0	0	0	5.44E-05	None	0	None	3.98E-06	0	0	0	None	N	-1.969(TCAP)
93	88	A/V	rs1473207810	0.0659	gnomAD-4.0.0	172	None	0.4902	0.507	25.9	D	-0.094	-0.33	0.013725	-0.31	0.5024	-0.0038	0.462690307121	None	0.999769	0.624	0.594056560588	1.0	0.641351819038	-2.56	0.439	0.659	None	None	None	1.59052E-06	0	0	0	2.77285E-05	None	0	0	1.59052E-06	0	0	0	None	N	-1.969(TCAP)
94	89	E/D	None	0.2008	gnomAD-4.0.0	173	None	0.2308	0.2924	23.2	N	None	-0.4	0.012771	-0.798	0.3356	-0.7023	0.431244382578	None	0.925696	0.463	0.483374165343	0.993	0.671121239662	-1.92	0.335	0.494	0.026	None	None	6.84081E-07	0	0	0	2.51927E-05	None	0	0	6.84081E-07	0	0	0	None	N	-0.674(TCAP)
95	90	L/F	rs774434865	0.0891	gnomAD-2.1.1	174	None	0.7633	0.7794	24.8	D	-1.803	-0.05	0.024149	-1.449	0.5478	0.3469	0.482941457244	None	0.964974	0.594	0.669665416366	1.0	0.713932037354	-2.56	0.454	0.863	0.009	None	None	3.98E-06	0	0	0	0	None	0	None	3.98E-06	0	8.79E-06	0	None	N	-1.267(TCAP)
95	90	L/F	rs774434865	0.0891	gnomAD-3.1.2	174	None	0.7633	0.7794	24.8	D	-1.803	-0.05	0.024149	-1.449	0.5478	0.3469	0.482941457244	None	0.964974	0.594	0.669665416366	1.0	0.713932037354	-2.56	0.454	0.863	0.009	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	N	-1.267(TCAP)
95	90	L/F	rs774434865	0.0891	gnomAD-4.0.0	174	None	0.7633	0.7794	24.8	D	-1.803	-0.05	0.024149	-1.449	0.5478	0.3469	0.482941457244	None	0.964974	0.594	0.669665416366	1.0	0.713932037354	-2.56	0.454	0.863	0.009	None	None	2.56115E-06	1.6909E-05	0	0	0	None	0	0	2.56115E-06	2.39172E-06	0	0	None	N	-1.267(TCAP)
97	92	V/L	None	0.0860	gnomAD-4.0.0	177	None	0.6211	0.6224	21.6	D	None	-1.13	0.053365	-0.799	0.6497	0.6788	0.248207255185	None	0.813928	0.766	0.707868329428	0.927	0.644143342972	-1.88	0.605	0.72	0.072	None	None	6.84083E-07	0	0	0	0	None	0	0	6.84083E-07	0	1.15942E-05	0	None	N	-0.732(TCAP)
97	92	V/M	rs185921345	0.0860	gnomAD-2.1.1	177	None	0.8243	0.8778	None	D	-1.282	None	None	-0.78	None	None	None	None	None	None	None	1.0	None	None	0.623	0.865	None	None	None	2.59558E-03	1.60244E-04	0	9.64692E-04	5.02E-05	None	3.27E-05	None	2.59558E-03	2.29716E-02	8.13134E-04	4.98201E-03	None	N	-0.998(TCAP)
97	92	V/M	rs185921345	0.0860	gnomAD-3.1.2	177	None	0.8243	0.8778	None	D	-1.282	None	None	-0.78	None	None	None	None	None	None	None	1.0	None	None	0.623	0.865	None	None	None	1.99132E-03	1.68943E-04	0	1.15274E-03	7.69823E-04	None	2.3383E-02	0	1.99132E-03	5.5861E-04	0	9.5511E-04	None	N	-0.998(TCAP)
97	92	V/M	rs185921345	0.0860	1000 genomes	177	None	0.8243	0.8778	None	D	-1.282	None	None	-0.78	None	None	None	None	None	None	None	1.0	None	None	0.623	0.865	None	None	None	1.19808E-03	0	0	None	0	6E-03	None	None	1.19808E-03	None	0	None	None	N	-0.998(TCAP)
97	92	V/M	rs185921345	0.0860	gnomAD-4.0.0	177	None	0.8243	0.8778	None	D	-1.282	None	None	-0.78	None	None	None	None	None	None	None	1.0	None	None	0.623	0.865	None	None	None	1.17342E-03	1.86577E-04	1.666E-05	7.43093E-04	1.11413E-04	None	2.43822E-02	6.62252E-04	1.17342E-03	1.81357E-04	4.39213E-05	1.10386E-03	None	N	-0.998(TCAP)

Whole Population MAF	African (AFR)	Latin American (AMR)
Amish (AMS)	Ashkenazi Jewish (ASJ)	East Asian (EAS)
European/1KGP (EUR)	Finnish (FIN)	Middle Eastern (MDE)
Non-Finnish European (NFE)	South Asian (SAS)	Other (OTH)

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