10 | 20 | 30 | 40 | 50 | 60 | 70 | 80 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S | V | K | G | G | I | Q | I | M | A | G | K | T | L | R | I | P | A | V | V | T | G | R | P | V | P | T | K | V | W | T | K | E | E | G | E | L | D | K | D | R | V | V | I | D | N | V | G | T | K | S | E | L | I | I | K | D | A | L | R | K | D | H | G | R | Y | V | I | T | A | T | N | S | C | G | S | K | F | A | A | A | R | V | E | V |
Pin SAV |
Position |
Domain position |
SAV |
Structural Position |
RS |
Q(SASA) |
Disease |
Source |
MAF |
---|---|---|---|---|---|---|---|---|---|
17677 | 1 | S/C | 1 | None | 1.0110 | None | gnomAD-4.0.0 | 1.59294E-06 | |
17678 | 2 | V/F | 3 | rs1423968417 | 0.2762 | None | gnomAD-4.0.0 | 1.59292E-06 | |
17678 | 2 | V/L | 3 | None | 0.2762 | None | gnomAD-4.0.0 | 1.59292E-06 | |
17680 | 4 | G/D | 9 | rs779241909 | 0.8086 | None | gnomAD-3.1.2 | 6.58E-06 | |
17680 | 4 | G/D | 9 | rs779241909 | 0.8086 | None | gnomAD-4.0.0 | 2.04601E-05 | |
17680 | 4 | G/S | 9 | None | 0.8086 | None | gnomAD-4.0.0 | 1.59284E-06 | |
17681 | 5 | G/R | 11 | rs2055221235 | 0.3492 | None | gnomAD-4.0.0 | 1.36901E-06 | |
17682 | 6 | I/T | 13 | None | 0.2027 | None | gnomAD-4.0.0 | 2.40065E-06 | |
17683 | 7 | Q/K | 14 | None | 0.5486 | None | gnomAD-4.0.0 | 3.18579E-06 | |
17684 | 8 | I/V | 16 | rs1456939827 | 0.1638 | None | gnomAD-3.1.2 | 1.32E-05 | |
17684 | 8 | I/V | 16 | rs1456939827 | 0.1638 | None | gnomAD-4.0.0 | 8.05967E-06 | |
17685 | 9 | M/I | 18 | rs200387466 | 0.6200 | None | gnomAD-2.1.1 | 2.04339E-04 | |
17685 | 9 | M/I | 18 | rs200387466 | 0.6200 | None | gnomAD-3.1.2 | 6.71088E-04 | |
17685 | 9 | M/I | 18 | rs200387466 | 0.6200 | None | 1000 genomes | 7.98722E-04 | |
17685 | 9 | M/I | 18 | rs200387466 | 0.6200 | None | gnomAD-4.0.0 | 1.27707E-04 | |
17685 | 9 | M/K | 18 | None | 0.6200 | None | gnomAD-4.0.0 | 3.18548E-06 | |
17685 | 9 | M/T | 18 | rs1289030052 | 0.6200 | None | gnomAD-3.1.2 | 1.32E-05 | |
17685 | 9 | M/T | 18 | rs1289030052 | 0.6200 | None | gnomAD-4.0.0 | 6.41157E-06 | |
17685 | 9 | M/V | 18 | rs2055217957 | 0.6200 | None | gnomAD-3.1.2 | 1.32E-05 | |
17685 | 9 | M/V | 18 | rs2055217957 | 0.6200 | None | gnomAD-4.0.0 | 6.81979E-06 | |
17686 | 10 | A/S | 23 | rs1576364760 | 0.3827 | None | gnomAD-3.1.2 | 6.58E-06 | |
17686 | 10 | A/S | 23 | rs1576364760 | 0.3827 | None | gnomAD-4.0.0 | 3.84634E-06 | |
17687 | 11 | G/E | 24 | rs780672348 | 0.4109 | None | gnomAD-2.1.1 | 4.04E-06 | |
17687 | 11 | G/E | 24 | rs780672348 | 0.4109 | None | gnomAD-4.0.0 | 6.84476E-07 | |
17687 | 11 | G/V | 24 | rs780672348 | 0.4109 | None | gnomAD-2.1.1 | 2.15E-05 | |
17687 | 11 | G/V | 24 | rs780672348 | 0.4109 | None | gnomAD-3.1.2 | 3.95E-05 | |
17687 | 11 | G/V | 24 | rs780672348 | 0.4109 | None | gnomAD-4.0.0 | 3.53396E-05 | |
17688 | 12 | K/E | 25 | rs201675016 | 0.5439 | None | gnomAD-4.0.0 | 9.23365E-04 | |
17689 | 13 | T/A | 26 | None | 0.3511 | None | gnomAD-4.0.0 | 6.00164E-06 | |
17690 | 14 | L/P | 28 | rs370469461 | 0.1753 | None | gnomAD-2.1.1 | 8.08E-06 | |
17690 | 14 | L/P | 28 | rs370469461 | 0.1753 | None | gnomAD-3.1.2 | 3.29E-05 | |
17690 | 14 | L/P | 28 | rs370469461 | 0.1753 | None | gnomAD-4.0.0 | 7.69387E-06 | |
17691 | 15 | R/G | 29 | rs1450047709 | 0.4822 | None | gnomAD-2.1.1 | 4.04E-06 | |
17691 | 15 | R/G | 29 | rs1450047709 | 0.4822 | None | gnomAD-4.0.0 | 5.47579E-06 | |
17692 | 16 | I/V | 30 | rs753698005 | 0.1147 | None | gnomAD-2.1.1 | 4.04E-06 | |
17693 | 17 | P/L | 31 | rs1176166730 | 0.4309 | None | gnomAD-2.1.1 | 4.04E-06 | |
17693 | 17 | P/L | 31 | rs1176166730 | 0.4309 | None | gnomAD-4.0.0 | 1.59267E-06 | |
17693 | 17 | P/T | 31 | None | 0.4309 | None | gnomAD-4.0.0 | 1.20032E-06 | |
17694 | 18 | A/T | 33 | None | 0.2316 | None | gnomAD-4.0.0 | 1.20032E-06 | |
17695 | 19 | V/G | 34 | rs2055207996 | 0.5554 | None | gnomAD-3.1.2 | 6.58E-06 | |
17695 | 19 | V/G | 34 | rs2055207996 | 0.5554 | None | gnomAD-4.0.0 | 6.5786E-06 | |
17696 | 20 | V/A | 35 | rs764155048 | 0.2696 | None | gnomAD-4.0.0 | 3.18507E-06 | |
17696 | 20 | V/G | 35 | None | 0.2696 | None | gnomAD-4.0.0 | 1.59253E-06 | |
17696 | 20 | V/L | 35 | None | 0.2696 | None | gnomAD-4.0.0 | 1.20032E-06 | |
17698 | 22 | G/C | 40 | None | 0.3794 | None | gnomAD-4.0.0 | 6.84435E-07 | |
17698 | 22 | G/D | 40 | None | 0.3794 | None | gnomAD-4.0.0 | 1.36885E-06 | |
17698 | 22 | G/S | 40 | None | 0.3794 | None | gnomAD-4.0.0 | 6.84435E-07 | |
17699 | 23 | R/C | 41 | rs760963888 | 0.9596 | None | gnomAD-2.1.1 | 2.51E-05 | |
17699 | 23 | R/C | 41 | rs760963888 | 0.9596 | None | gnomAD-3.1.2 | 1.32E-05 | |
17699 | 23 | R/C | 41 | rs760963888 | 0.9596 | None | gnomAD-4.0.0 | 1.48798E-05 | |
17699 | 23 | R/H | 41 | None | 0.9596 | None | gnomAD-2.1.1 | 1.77036E-03 | |
17699 | 23 | R/H | 41 | None | 0.9596 | None | gnomAD-3.1.2 | 1.58636E-03 | |
17699 | 23 | R/H | 41 | None | 0.9596 | None | 1000 genomes | 1.19808E-03 | |
17699 | 23 | R/H | 41 | None | 0.9596 | None | gnomAD-4.0.0 | 2.24162E-03 | |
17699 | 23 | R/L | 41 | rs72646808 | 0.9596 | None | gnomAD-2.1.1 | 4.04E-06 | |
17699 | 23 | R/L | 41 | rs72646808 | 0.9596 | None | gnomAD-4.0.0 | 1.36885E-06 | |
17699 | 23 | R/P | 41 | rs72646808 | 0.9596 | None | gnomAD-3.1.2 | 1.32E-05 | |
17699 | 23 | R/P | 41 | rs72646808 | 0.9596 | None | gnomAD-4.0.0 | 1.85989E-06 | |
17700 | 24 | P/L | 42 | rs767647740 | 0.4908 | None | gnomAD-2.1.1 | 4.04E-06 | |
17700 | 24 | P/L | 42 | rs767647740 | 0.4908 | None | gnomAD-4.0.0 | 1.59242E-06 | |
17701 | 25 | V/E | 43 | rs1484367786 | 0.8333 | None | gnomAD-2.1.1 | 8.07E-06 | |
17701 | 25 | V/E | 43 | rs1484367786 | 0.8333 | None | gnomAD-4.0.0 | 4.77705E-06 | |
17701 | 25 | V/I | 43 | rs1481397518 | 0.8333 | None | gnomAD-3.1.2 | 1.32E-05 | |
17701 | 25 | V/I | 43 | rs1481397518 | 0.8333 | None | gnomAD-4.0.0 | 6.19941E-06 | |
17702 | 26 | P/S | 44 | rs1238325853 | 0.2305 | None | gnomAD-2.1.1 | 4.04E-06 | |
17702 | 26 | P/S | 44 | rs1238325853 | 0.2305 | None | gnomAD-4.0.0 | 1.59243E-06 | |
17703 | 27 | T/A | 45 | None | 0.6438 | None | gnomAD-4.0.0 | 1.59233E-06 | |
17703 | 27 | T/S | 45 | None | 0.6438 | None | gnomAD-4.0.0 | 1.59233E-06 | |
17704 | 28 | K/E | 46 | None | 0.2928 | None | gnomAD-4.0.0 | 4.10637E-06 | |
17705 | 29 | V/I | 47 | None | 0.6160 | None | gnomAD-4.0.0 | 4.77693E-06 | |
17707 | 31 | T/A | 49 | None | 0.4862 | None | gnomAD-4.0.0 | 1.5923E-06 | |
17707 | 31 | T/N | 49 | rs2055199446 | 0.4862 | None | gnomAD-3.1.2 | 6.59E-06 | |
17707 | 31 | T/N | 49 | rs2055199446 | 0.4862 | None | gnomAD-4.0.0 | 6.58874E-06 | |
17708 | 32 | K/E | 50 | rs185913848 | 0.1788 | None | gnomAD-2.1.1 | 3.72269E-04 | |
17708 | 32 | K/E | 50 | rs185913848 | 0.1788 | None | gnomAD-3.1.2 | 4.27682E-04 | |
17708 | 32 | K/E | 50 | rs185913848 | 0.1788 | None | 1000 genomes | 7.98722E-04 | |
17708 | 32 | K/E | 50 | rs185913848 | 0.1788 | None | gnomAD-4.0.0 | 7.12853E-04 | |
17708 | 32 | K/I | 50 | rs2303832 | 0.1788 | None | gnomAD-2.1.1 | 2.86276E-02 | |
17708 | 32 | K/I | 50 | rs2303832 | 0.1788 | None | gnomAD-3.1.2 | 2.13591E-02 | |
17708 | 32 | K/I | 50 | rs2303832 | 0.1788 | None | 1000 genomes | 2.95527E-02 | |
17708 | 32 | K/I | 50 | rs2303832 | 0.1788 | None | gnomAD-4.0.0 | 2.35557E-02 | |
17710 | 34 | E/D | 52 | rs749551895 | 1.0753 | None | gnomAD-2.1.1 | 3.19E-05 | |
17710 | 34 | E/D | 52 | rs749551895 | 1.0753 | None | gnomAD-3.1.2 | 6.58E-06 | |
17710 | 34 | E/D | 52 | rs749551895 | 1.0753 | None | gnomAD-4.0.0 | 6.57964E-06 | |
17711 | 35 | G/R | 55 | rs773642381 | 0.4146 | None | gnomAD-2.1.1 | 7.16E-06 | |
17711 | 35 | G/R | 55 | rs773642381 | 0.4146 | None | gnomAD-3.1.2 | 6.58E-06 | |
17711 | 35 | G/R | 55 | rs773642381 | 0.4146 | None | gnomAD-4.0.0 | 3.09969E-06 | |
17712 | 36 | E/K | 56 | None | 0.9123 | None | gnomAD-4.0.0 | 1.59239E-06 | |
17713 | 37 | L/V | 58 | rs1008171003 | 0.2742 | None | gnomAD-3.1.2 | 6.58E-06 | |
17713 | 37 | L/V | 58 | rs1008171003 | 0.2742 | None | gnomAD-4.0.0 | 2.56432E-06 | |
17714 | 38 | D/N | 59 | None | 0.3679 | None | gnomAD-4.0.0 | 6.84404E-07 | |
17714 | 38 | D/Y | 59 | rs1051253179 | 0.3679 | None | gnomAD-2.1.1 | 1.21E-05 | |
17714 | 38 | D/Y | 59 | rs1051253179 | 0.3679 | None | gnomAD-4.0.0 | 1.23193E-05 | |
17715 | 39 | K/E | 70 | None | 0.7437 | None | gnomAD-4.0.0 | 1.59232E-06 | |
17715 | 39 | K/N | 70 | rs2055193492 | 0.7437 | None | gnomAD-3.1.2 | 6.58E-06 | |
17715 | 39 | K/N | 70 | rs2055193492 | 0.7437 | None | gnomAD-4.0.0 | 6.57843E-06 | |
17716 | 40 | D/N | 109 | rs1576363473 | 0.9772 | None | gnomAD-3.1.2 | 6.58E-06 | |
17716 | 40 | D/N | 109 | rs1576363473 | 0.9772 | None | gnomAD-4.0.0 | 6.58033E-06 | |
17717 | 41 | R/C | 115 | rs369001587 | 0.2831 | None | gnomAD-2.1.1 | 1.61E-05 | |
17717 | 41 | R/C | 115 | rs369001587 | 0.2831 | None | gnomAD-3.1.2 | 6.58E-06 | |
17717 | 41 | R/C | 115 | rs369001587 | 0.2831 | None | gnomAD-4.0.0 | 7.43944E-06 | |
17717 | 41 | R/H | 115 | rs757018821 | 0.2831 | None | gnomAD-2.1.1 | 5.72E-05 | |
17717 | 41 | R/H | 115 | rs757018821 | 0.2831 | None | gnomAD-3.1.2 | 6.58E-05 | |
17717 | 41 | R/H | 115 | rs757018821 | 0.2831 | None | gnomAD-4.0.0 | 2.54175E-05 | |
17717 | 41 | R/P | 115 | rs757018821 | 0.2831 | None | gnomAD-2.1.1 | 7.15E-06 | |
17717 | 41 | R/P | 115 | rs757018821 | 0.2831 | None | gnomAD-3.1.2 | 6.58E-06 | |
17717 | 41 | R/P | 115 | rs757018821 | 0.2831 | None | gnomAD-4.0.0 | 1.23988E-06 | |
17718 | 42 | V/F | 121 | rs757223139 | 0.1962 | None | gnomAD-2.1.1 | 4.03E-06 | |
17718 | 42 | V/F | 121 | rs757223139 | 0.1962 | None | gnomAD-4.0.0 | 1.59229E-06 | |
17718 | 42 | V/G | 121 | None | 0.1962 | None | gnomAD-4.0.0 | 2.05322E-06 | |
17718 | 42 | V/I | 121 | rs757223139 | 0.1962 | None | gnomAD-2.1.1 | 4.03E-06 | |
17718 | 42 | V/I | 121 | rs757223139 | 0.1962 | None | gnomAD-3.1.2 | 6.58E-06 | |
17718 | 42 | V/I | 121 | rs757223139 | 0.1962 | None | gnomAD-4.0.0 | 6.57929E-06 | |
17719 | 43 | V/A | 122 | rs564121832 | 0.5711 | None | gnomAD-2.1.1 | 1.28815E-04 | |
17719 | 43 | V/A | 122 | rs564121832 | 0.5711 | None | gnomAD-3.1.2 | 3.29E-05 | |
17719 | 43 | V/A | 122 | rs564121832 | 0.5711 | None | 1000 genomes | 1.99681E-04 | |
17719 | 43 | V/A | 122 | rs564121832 | 0.5711 | None | gnomAD-4.0.0 | 7.43864E-05 | |
17720 | 44 | I/M | 123 | None | 0.3378 | None | gnomAD-4.0.0 | 1.59221E-06 | |
17720 | 44 | I/T | 123 | rs201358641 | 0.3378 | None | gnomAD-2.1.1 | 2.85914E-04 | |
17720 | 44 | I/T | 123 | rs201358641 | 0.3378 | None | gnomAD-3.1.2 | 2.82988E-04 | |
17720 | 44 | I/T | 123 | rs201358641 | 0.3378 | None | gnomAD-4.0.0 | 1.84118E-04 | |
17721 | 45 | D/V | 125 | None | 0.6614 | None | gnomAD-4.0.0 | 1.20032E-06 | |
17723 | 47 | V/A | 130 | rs1420844949 | 0.7593 | None | gnomAD-3.1.2 | 6.58E-06 | |
17723 | 47 | V/A | 130 | rs1420844949 | 0.7593 | None | gnomAD-4.0.0 | 5.57955E-06 | |
17723 | 47 | V/D | 130 | rs1420844949 | 0.7593 | None | gnomAD-2.1.1 | 4.02E-06 | |
17723 | 47 | V/D | 130 | rs1420844949 | 0.7593 | None | gnomAD-4.0.0 | 1.3688E-06 | |
17723 | 47 | V/I | 130 | rs2055183327 | 0.7593 | None | gnomAD-4.0.0 | 4.10644E-06 | |
17723 | 47 | V/L | 130 | None | 0.7593 | None | gnomAD-4.0.0 | 6.84406E-07 | |
17724 | 48 | G/E | 131 | None | 0.5107 | None | gnomAD-4.0.0 | 1.36881E-06 | |
17724 | 48 | G/V | 131 | rs1385094780 | 0.5107 | None | gnomAD-2.1.1 | 4.02E-06 | |
17724 | 48 | G/V | 131 | rs1385094780 | 0.5107 | None | gnomAD-4.0.0 | 6.84406E-07 | |
17725 | 49 | T/I | 134 | None | 0.4821 | None | gnomAD-4.0.0 | 1.59231E-06 | |
17727 | 51 | S/C | 136 | rs369262757 | 0.1373 | None | gnomAD-2.1.1 | 3.57E-05 | |
17727 | 51 | S/C | 136 | rs369262757 | 0.1373 | None | gnomAD-3.1.2 | 3.29E-05 | |
17727 | 51 | S/C | 136 | rs369262757 | 0.1373 | None | gnomAD-4.0.0 | 1.61167E-05 | |
17728 | 52 | E/K | 137 | None | 0.2768 | None | gnomAD-4.0.0 | 6.84391E-07 | |
17729 | 53 | L/V | 138 | rs767559716 | 0.0916 | None | gnomAD-2.1.1 | 4.02E-06 | |
17729 | 53 | L/V | 138 | rs767559716 | 0.0916 | None | gnomAD-4.0.0 | 6.84397E-07 | |
17730 | 54 | I/T | 139 | rs1337110210 | 0.2061 | None | gnomAD-2.1.1 | 3.19E-05 | |
17730 | 54 | I/T | 139 | rs1337110210 | 0.2061 | None | gnomAD-3.1.2 | 6.58E-06 | |
17730 | 54 | I/T | 139 | rs1337110210 | 0.2061 | None | gnomAD-4.0.0 | 6.58042E-06 | |
17730 | 54 | I/V | 139 | None | 0.2061 | None | gnomAD-4.0.0 | 3.18454E-06 | |
17731 | 55 | I/N | 140 | rs72646809 | 0.1565 | None | gnomAD-2.1.1 | 4.02E-06 | |
17731 | 55 | I/N | 140 | rs72646809 | 0.1565 | None | gnomAD-4.0.0 | 1.36878E-06 | |
17731 | 55 | I/T | 140 | rs72646809 | 0.1565 | None | gnomAD-2.1.1 | 1.37245E-02 | |
17731 | 55 | I/T | 140 | rs72646809 | 0.1565 | None | gnomAD-3.1.2 | 1.10997E-02 | |
17731 | 55 | I/T | 140 | rs72646809 | 0.1565 | None | 1000 genomes | 4.59265E-03 | |
17731 | 55 | I/T | 140 | rs72646809 | 0.1565 | None | gnomAD-4.0.0 | 1.1447E-02 | |
17731 | 55 | I/V | 140 | None | 0.1565 | None | gnomAD-4.0.0 | 1.59225E-06 | |
17732 | 56 | K/R | 141 | rs2055177922 | 0.8491 | None | gnomAD-3.1.2 | 6.58E-06 | |
17732 | 56 | K/R | 141 | rs2055177922 | 0.8491 | None | gnomAD-4.0.0 | 6.57808E-06 | |
17733 | 57 | D/E | 143 | None | 0.6004 | None | gnomAD-4.0.0 | 2.40064E-06 | |
17734 | 58 | A/T | 144 | None | 0.1184 | None | gnomAD-4.0.0 | 1.59228E-06 | |
17736 | 60 | R/G | 146 | rs571702144 | 0.6686 | None | gnomAD-2.1.1 | 4.02E-06 | |
17736 | 60 | R/G | 146 | rs571702144 | 0.6686 | None | gnomAD-3.1.2 | 6.58E-06 | |
17736 | 60 | R/G | 146 | rs571702144 | 0.6686 | None | 1000 genomes | 1.99681E-04 | |
17736 | 60 | R/G | 146 | rs571702144 | 0.6686 | None | gnomAD-4.0.0 | 6.57834E-06 | |
17736 | 60 | R/Q | 146 | rs766817830 | 0.6686 | None | gnomAD-2.1.1 | 6.84E-05 | |
17736 | 60 | R/Q | 146 | rs766817830 | 0.6686 | None | gnomAD-3.1.2 | 1.32E-05 | |
17736 | 60 | R/Q | 146 | rs766817830 | 0.6686 | None | gnomAD-4.0.0 | 2.66565E-05 | |
17738 | 62 | D/G | 149 | rs773447539 | 0.1821 | None | gnomAD-2.1.1 | 4.02E-06 | |
17738 | 62 | D/G | 149 | rs773447539 | 0.1821 | None | gnomAD-4.0.0 | 6.84395E-07 | |
17738 | 62 | D/V | 149 | rs773447539 | 0.1821 | None | gnomAD-2.1.1 | 4.83E-05 | |
17738 | 62 | D/V | 149 | rs773447539 | 0.1821 | None | gnomAD-3.1.2 | 3.29E-05 | |
17738 | 62 | D/V | 149 | rs773447539 | 0.1821 | None | gnomAD-4.0.0 | 2.23165E-05 | |
17739 | 63 | H/L | 151 | None | 0.5695 | None | gnomAD-4.0.0 | 1.20032E-06 | |
17739 | 63 | H/N | 151 | rs1419607621 | 0.5695 | None | gnomAD-2.1.1 | 3.19E-05 | |
17739 | 63 | H/N | 151 | rs1419607621 | 0.5695 | None | gnomAD-3.1.2 | 1.32E-05 | |
17739 | 63 | H/N | 151 | rs1419607621 | 0.5695 | None | gnomAD-4.0.0 | 7.69235E-06 | |
17739 | 63 | H/R | 151 | rs1488100561 | 0.5695 | None | gnomAD-3.1.2 | 6.58E-06 | |
17739 | 63 | H/R | 151 | rs1488100561 | 0.5695 | None | gnomAD-4.0.0 | 6.57722E-06 | |
17740 | 64 | G/D | 152 | rs1219250375 | 0.2099 | None | gnomAD-2.1.1 | 8.04E-06 | |
17740 | 64 | G/D | 152 | rs1219250375 | 0.2099 | None | gnomAD-3.1.2 | 6.58E-06 | |
17740 | 64 | G/D | 152 | rs1219250375 | 0.2099 | None | gnomAD-4.0.0 | 3.84626E-06 | |
17741 | 65 | R/G | 153 | rs1189355872 | 0.3560 | None | gnomAD-3.1.2 | 6.58E-06 | |
17741 | 65 | R/G | 153 | rs1189355872 | 0.3560 | None | gnomAD-4.0.0 | 6.578E-06 | |
17742 | 66 | Y/C | 154 | None | 0.1624 | None | gnomAD-4.0.0 | 1.59243E-06 | |
17743 | 67 | V/L | 155 | None | 0.1624 | None | gnomAD-4.0.0 | 6.84428E-07 | |
17743 | 67 | V/M | 155 | None | 0.1624 | None | gnomAD-4.0.0 | 1.36886E-06 | |
17745 | 69 | T/I | 157 | rs879245504 | 0.3255 | None | gnomAD-4.0.0 | 1.36887E-06 | |
17745 | 69 | T/K | 157 | rs879245504 | 0.3255 | None | gnomAD-2.1.1 | 4.02E-06 | |
17745 | 69 | T/K | 157 | rs879245504 | 0.3255 | None | gnomAD-4.0.0 | 6.84435E-07 | |
17746 | 70 | A/T | 158 | rs886055266 | 0.1768 | None | gnomAD-4.0.0 | 1.59247E-06 | |
17748 | 72 | N/D | 161 | rs1279556849 | 0.1919 | None | gnomAD-2.1.1 | 4.02E-06 | |
17748 | 72 | N/D | 161 | rs1279556849 | 0.1919 | None | gnomAD-4.0.0 | 1.59247E-06 | |
17749 | 73 | S/C | 162 | rs2055164382 | 0.6460 | None | gnomAD-3.1.2 | 6.58E-06 | |
17749 | 73 | S/C | 162 | rs2055164382 | 0.6460 | None | gnomAD-4.0.0 | 6.57722E-06 | |
17749 | 73 | S/N | 162 | rs1553686153 | 0.6460 | None | gnomAD-4.0.0 | 6.84432E-07 | |
17749 | 73 | S/T | 162 | rs1553686153 | 0.6460 | None | gnomAD-3.1.2 | 6.58E-06 | |
17749 | 73 | S/T | 162 | rs1553686153 | 0.6460 | None | gnomAD-4.0.0 | 4.33955E-06 | |
17750 | 74 | C/Y | 163 | rs1666217095 | 0.6378 | None | gnomAD-4.0.0 | 4.79106E-06 | |
17751 | 75 | G/D | 164 | None | 0.3511 | None | gnomAD-4.0.0 | 1.36888E-06 | |
17751 | 75 | G/R | 164 | None | 0.3511 | None | gnomAD-4.0.0 | 1.20032E-06 | |
17753 | 77 | K/N | 166 | rs1456581218 | 0.7993 | None | gnomAD-2.1.1 | 6.38E-05 | |
17753 | 77 | K/N | 166 | rs1456581218 | 0.7993 | None | gnomAD-3.1.2 | 6.58E-06 | |
17753 | 77 | K/N | 166 | rs1456581218 | 0.7993 | None | gnomAD-4.0.0 | 6.57782E-06 | |
17753 | 77 | K/R | 166 | None | 0.7993 | None | gnomAD-4.0.0 | 1.20032E-06 | |
17754 | 78 | F/L | 168 | rs397517612 | 0.6958 | None | gnomAD-2.1.1 | 7.936E-04 | |
17754 | 78 | F/L | 168 | rs397517612 | 0.6958 | None | gnomAD-3.1.2 | 1.64441E-04 | |
17754 | 78 | F/L | 168 | rs397517612 | 0.6958 | None | 1000 genomes | 3.99361E-04 | |
17754 | 78 | F/L | 168 | rs397517612 | 0.6958 | None | gnomAD-4.0.0 | 3.57058E-04 | |
17754 | 78 | F/S | 168 | rs749312983 | 0.6958 | None | gnomAD-2.1.1 | 1.46566E-04 | |
17754 | 78 | F/S | 168 | rs749312983 | 0.6958 | None | gnomAD-3.1.2 | 2.63E-05 | |
17754 | 78 | F/S | 168 | rs749312983 | 0.6958 | None | gnomAD-4.0.0 | 3.16146E-05 | |
17755 | 79 | A/V | 169 | rs777396852 | 0.4414 | None | gnomAD-2.1.1 | 4.03E-06 | |
17757 | 81 | A/V | 172 | rs1351014934 | 0.2255 | None | gnomAD-3.1.2 | 1.32E-05 | |
17757 | 81 | A/V | 172 | rs1351014934 | 0.2255 | None | gnomAD-4.0.0 | 3.72001E-06 | |
17758 | 82 | R/M | 173 | None | 0.6280 | None | gnomAD-4.0.0 | 1.20032E-06 | |
17758 | 82 | R/S | 173 | rs755982578 | 0.6280 | None | gnomAD-2.1.1 | 4.03E-06 | |
17759 | 83 | V/L | 174 | rs752508699 | 0.1235 | None | gnomAD-2.1.1 | 4.03E-06 | |
17759 | 83 | V/L | 174 | rs752508699 | 0.1235 | None | gnomAD-4.0.0 | 1.59268E-06 | |
17760 | 84 | E/G | 175 | rs2055156080 | 0.3043 | None | gnomAD-4.0.0 | 1.20032E-06 | |
17760 | 84 | E/Q | 175 | None | 0.3043 | None | gnomAD-4.0.0 | 1.5927E-06 | |
17761 | 85 | V/I | 177 | None | 0.1399 | None | gnomAD-4.0.0 | 1.20032E-06 |