10 | 20 | 30 | 40 | 50 | 60 | 70 | 80 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
A | D | L | R | K | T | L | I | L | R | A | G | V | T | M | R | L | Y | V | P | V | K | G | R | P | P | P | K | I | T | W | S | K | P | N | V | N | L | R | D | R | I | G | L | D | I | K | S | T | D | F | D | T | F | L | R | C | E | N | V | N | K | Y | D | A | G | K | Y | I | L | T | L | E | N | S | C | G | K | K | E | Y | T | I | V | V | K | V |
Pin SAV |
Position |
Domain position |
SAV |
Structural Position |
RS |
Q(SASA) |
Disease |
Source |
MAF |
---|---|---|---|---|---|---|---|---|---|
22265 | 1 | A/E | 1 | rs750836266 | 0.6057 | None | gnomAD-2.1.1 | 4.1E-06 | |
22265 | 1 | A/E | 1 | rs750836266 | 0.6057 | None | gnomAD-4.0.0 | 2.05737E-06 | |
22265 | 1 | A/V | 1 | rs750836266 | 0.6057 | None | gnomAD-2.1.1 | 1.76336E-04 | |
22265 | 1 | A/V | 1 | rs750836266 | 0.6057 | None | gnomAD-3.1.2 | 3.29E-05 | |
22265 | 1 | A/V | 1 | rs750836266 | 0.6057 | None | gnomAD-4.0.0 | 8.07281E-05 | |
22266 | 2 | D/E | 2 | rs1380514691 | 0.9018 | None | gnomAD-2.1.1 | 4.08E-06 | |
22266 | 2 | D/E | 2 | rs1380514691 | 0.9018 | None | gnomAD-4.0.0 | 6.8535E-07 | |
22266 | 2 | D/N | 2 | None | 0.9018 | None | gnomAD-4.0.0 | 1.59782E-06 | |
22267 | 3 | L/F | 3 | None | 0.4216 | None | gnomAD-4.0.0 | 6.00161E-06 | |
22267 | 3 | L/V | 3 | rs2047467228 | 0.4216 | None | gnomAD-4.0.0 | 1.37066E-06 | |
22268 | 4 | R/G | 4 | rs762044819 | 0.8166 | None | gnomAD-2.1.1 | 4.07E-06 | |
22268 | 4 | R/G | 4 | rs762044819 | 0.8166 | None | gnomAD-4.0.0 | 1.59682E-06 | |
22268 | 4 | R/K | 4 | None | 0.8166 | None | gnomAD-4.0.0 | 6.85231E-07 | |
22268 | 4 | R/M | 4 | None | 0.8166 | None | gnomAD-4.0.0 | 2.05569E-06 | |
22270 | 6 | T/I | 11 | rs2047465405 | 0.4518 | None | gnomAD-3.1.2 | 6.58E-06 | |
22270 | 6 | T/I | 11 | rs2047465405 | 0.4518 | None | gnomAD-4.0.0 | 6.57514E-06 | |
22271 | 7 | L/F | 13 | rs2047464424 | 0.3349 | None | gnomAD-4.0.0 | 2.73965E-06 | |
22271 | 7 | L/I | 13 | rs2047464424 | 0.3349 | None | gnomAD-3.1.2 | 6.57E-06 | |
22271 | 7 | L/I | 13 | rs2047464424 | 0.3349 | None | gnomAD-4.0.0 | 6.57471E-06 | |
22271 | 7 | L/R | 13 | None | 0.3349 | None | gnomAD-4.0.0 | 1.20033E-06 | |
22271 | 7 | L/V | 13 | None | 0.3349 | None | gnomAD-4.0.0 | 6.84913E-07 | |
22272 | 8 | I/M | 14 | rs1460711951 | 0.5092 | None | gnomAD-3.1.2 | 6.57E-06 | |
22272 | 8 | I/M | 14 | rs1460711951 | 0.5092 | None | gnomAD-4.0.0 | 2.03001E-06 | |
22272 | 8 | I/T | 14 | rs773998250 | 0.5092 | None | gnomAD-2.1.1 | 2.03E-05 | |
22272 | 8 | I/T | 14 | rs773998250 | 0.5092 | None | gnomAD-3.1.2 | 1.97E-05 | |
22272 | 8 | I/T | 14 | rs773998250 | 0.5092 | None | gnomAD-4.0.0 | 1.48854E-05 | |
22273 | 9 | L/I | 16 | None | 0.2285 | None | gnomAD-4.0.0 | 1.5946E-06 | |
22274 | 10 | R/C | 18 | rs770627108 | 0.7343 | None | gnomAD-2.1.1 | 8.11E-06 | |
22274 | 10 | R/C | 18 | rs770627108 | 0.7343 | None | gnomAD-3.1.2 | 1.32E-05 | |
22274 | 10 | R/C | 18 | rs770627108 | 0.7343 | None | gnomAD-4.0.0 | 2.35703E-05 | |
22274 | 10 | R/H | 18 | None | 0.7343 | None | gnomAD-2.1.1 | 1.21E-05 | |
22274 | 10 | R/H | 18 | None | 0.7343 | None | gnomAD-4.0.0 | 9.58641E-06 | |
22274 | 10 | R/L | 18 | rs772979195 | 0.7343 | None | gnomAD-2.1.1 | 1.62E-05 | |
22274 | 10 | R/L | 18 | rs772979195 | 0.7343 | None | gnomAD-3.1.2 | 6.58E-06 | |
22274 | 10 | R/L | 18 | rs772979195 | 0.7343 | None | gnomAD-4.0.0 | 2.48069E-06 | |
22275 | 11 | A/P | 23 | None | 0.3822 | None | gnomAD-4.0.0 | 1.20034E-06 | |
22275 | 11 | A/V | 23 | rs781002289 | 0.3822 | None | gnomAD-2.1.1 | 1.21E-05 | |
22275 | 11 | A/V | 23 | rs781002289 | 0.3822 | None | gnomAD-4.0.0 | 1.20033E-06 | |
22277 | 13 | V/A | 25 | rs768860754 | 0.2922 | None | gnomAD-2.1.1 | 4.05E-06 | |
22278 | 14 | T/I | 26 | rs1449367862 | 0.2674 | None | gnomAD-2.1.1 | 4.04E-06 | |
22278 | 14 | T/I | 26 | rs1449367862 | 0.2674 | None | gnomAD-4.0.0 | 7.96889E-06 | |
22279 | 15 | M/R | 28 | rs758406122 | 0.1224 | None | gnomAD-2.1.1 | 1.62E-05 | |
22279 | 15 | M/R | 28 | rs758406122 | 0.1224 | None | gnomAD-4.0.0 | 6.162E-06 | |
22279 | 15 | M/V | 28 | rs780268398 | 0.1224 | None | gnomAD-2.1.1 | 1.62E-05 | |
22279 | 15 | M/V | 28 | rs780268398 | 0.1224 | None | gnomAD-4.0.0 | 4.10802E-06 | |
22282 | 18 | Y/H | 31 | rs745992545 | 0.4214 | None | gnomAD-2.1.1 | 2.87E-05 | |
22282 | 18 | Y/H | 31 | rs745992545 | 0.4214 | None | gnomAD-3.1.2 | 9.86E-05 | |
22282 | 18 | Y/H | 31 | rs745992545 | 0.4214 | None | gnomAD-4.0.0 | 1.67421E-05 | |
22283 | 19 | V/A | 33 | rs1246688280 | 0.2268 | None | gnomAD-2.1.1 | 4.04E-06 | |
22283 | 19 | V/A | 33 | rs1246688280 | 0.2268 | None | gnomAD-4.0.0 | 1.59361E-06 | |
22283 | 19 | V/I | 33 | rs554828165 | 0.2268 | None | gnomAD-2.1.1 | 2.83E-05 | |
22283 | 19 | V/I | 33 | rs554828165 | 0.2268 | None | gnomAD-3.1.2 | 1.31E-05 | |
22283 | 19 | V/I | 33 | rs554828165 | 0.2268 | None | 1000 genomes | 1.99681E-04 | |
22283 | 19 | V/I | 33 | rs554828165 | 0.2268 | None | gnomAD-4.0.0 | 1.4261E-05 | |
22284 | 20 | P/L | 34 | None | 0.4402 | None | gnomAD-4.0.0 | 6.16186E-06 | |
22284 | 20 | P/S | 34 | None | 0.4402 | None | gnomAD-4.0.0 | 1.36929E-06 | |
22284 | 20 | P/T | 34 | None | 0.4402 | None | gnomAD-4.0.0 | 6.84644E-07 | |
22285 | 21 | V/I | 35 | None | 0.1732 | None | gnomAD-4.0.0 | 6.84633E-07 | |
22285 | 21 | V/L | 35 | rs754121833 | 0.1732 | None | gnomAD-2.1.1 | 4.04E-06 | |
22285 | 21 | V/L | 35 | rs754121833 | 0.1732 | None | gnomAD-4.0.0 | 6.84633E-07 | |
22287 | 23 | G/R | 40 | rs1268203596 | 0.2900 | None | gnomAD-2.1.1 | 4.04E-06 | |
22287 | 23 | G/R | 40 | rs1268203596 | 0.2900 | None | gnomAD-4.0.0 | 3.4231E-06 | |
22288 | 24 | R/C | 41 | rs367665060 | 0.4442 | None | gnomAD-2.1.1 | 2.87E-05 | |
22288 | 24 | R/C | 41 | rs367665060 | 0.4442 | None | gnomAD-3.1.2 | 5.26E-05 | |
22288 | 24 | R/C | 41 | rs367665060 | 0.4442 | None | gnomAD-4.0.0 | 2.17031E-05 | |
22288 | 24 | R/H | 41 | rs537871205 | 0.4442 | None | gnomAD-2.1.1 | 2.15E-05 | |
22288 | 24 | R/H | 41 | rs537871205 | 0.4442 | None | gnomAD-3.1.2 | 3.29E-05 | |
22288 | 24 | R/H | 41 | rs537871205 | 0.4442 | None | 1000 genomes | 1.99681E-04 | |
22288 | 24 | R/H | 41 | rs537871205 | 0.4442 | None | gnomAD-4.0.0 | 1.17806E-05 | |
22288 | 24 | R/S | 41 | None | 0.4442 | None | gnomAD-4.0.0 | 1.36923E-06 | |
22289 | 25 | P/L | 42 | rs751203353 | 0.4555 | None | gnomAD-2.1.1 | 4.04E-06 | |
22289 | 25 | P/L | 42 | rs751203353 | 0.4555 | None | gnomAD-4.0.0 | 1.59339E-06 | |
22290 | 26 | P/S | 43 | None | 0.3883 | None | gnomAD-4.0.0 | 1.59328E-06 | |
22291 | 27 | P/T | 44 | None | 0.1882 | None | gnomAD-4.0.0 | 3.18653E-06 | |
22292 | 28 | K/T | 45 | None | 0.6829 | None | gnomAD-4.0.0 | 1.20032E-06 | |
22293 | 29 | I/T | 46 | rs766138542 | 0.1953 | None | gnomAD-2.1.1 | 4.03E-06 | |
22293 | 29 | I/T | 46 | rs766138542 | 0.1953 | None | gnomAD-4.0.0 | 1.59312E-06 | |
22294 | 30 | T/S | 47 | rs2047448209 | 0.4081 | None | gnomAD-4.0.0 | 2.05367E-06 | |
22295 | 31 | W/C | 48 | rs1202934929 | 0.2497 | None | gnomAD-3.1.2 | 6.58E-06 | |
22295 | 31 | W/C | 48 | rs1202934929 | 0.2497 | None | gnomAD-4.0.0 | 2.56498E-06 | |
22296 | 32 | S/C | 49 | None | 0.3366 | None | gnomAD-4.0.0 | 1.5931E-06 | |
22297 | 33 | K/N | 50 | rs1013098448 | 0.1375 | None | gnomAD-3.1.2 | 6.58E-06 | |
22297 | 33 | K/N | 50 | rs1013098448 | 0.1375 | None | gnomAD-4.0.0 | 6.57583E-06 | |
22298 | 34 | P/S | 51 | rs72646871 | 0.4896 | None | gnomAD-2.1.1 | 8.06E-06 | |
22298 | 34 | P/S | 51 | rs72646871 | 0.4896 | None | gnomAD-4.0.0 | 4.77931E-06 | |
22300 | 36 | V/I | 55 | rs200343420 | 0.3709 | None | gnomAD-2.1.1 | 3.75668E-04 | |
22300 | 36 | V/I | 55 | rs200343420 | 0.3709 | None | gnomAD-3.1.2 | 1.00638E-03 | |
22300 | 36 | V/I | 55 | rs200343420 | 0.3709 | None | 1000 genomes | 3.99361E-04 | |
22300 | 36 | V/I | 55 | rs200343420 | 0.3709 | None | gnomAD-4.0.0 | 1.81648E-04 | |
22301 | 37 | N/S | 56 | rs772823241 | 0.4352 | None | gnomAD-2.1.1 | 1.21E-05 | |
22301 | 37 | N/S | 56 | rs772823241 | 0.4352 | None | gnomAD-3.1.2 | 1.97E-05 | |
22301 | 37 | N/S | 56 | rs772823241 | 0.4352 | None | gnomAD-4.0.0 | 3.03787E-05 | |
22304 | 40 | D/N | 70 | None | 0.6299 | None | gnomAD-4.0.0 | 1.59281E-06 | |
22305 | 41 | R/G | 73 | None | 0.1618 | None | gnomAD-4.0.0 | 1.20032E-06 | |
22305 | 41 | R/T | 73 | None | 0.1618 | None | gnomAD-4.0.0 | 1.59277E-06 | |
22306 | 42 | I/F | 102 | None | 1.1151 | None | gnomAD-4.0.0 | 1.59274E-06 | |
22306 | 42 | I/N | 102 | None | 1.1151 | None | gnomAD-4.0.0 | 1.36895E-06 | |
22306 | 42 | I/T | 102 | rs397517667 | 1.1151 | None | gnomAD-2.1.1 | 2.32447E-04 | |
22306 | 42 | I/T | 102 | rs397517667 | 1.1151 | None | gnomAD-3.1.2 | 1.11844E-04 | |
22306 | 42 | I/T | 102 | rs397517667 | 1.1151 | None | gnomAD-4.0.0 | 1.14075E-04 | |
22308 | 44 | L/P | 121 | None | 0.2271 | None | gnomAD-4.0.0 | 1.20032E-06 | |
22309 | 45 | D/A | 122 | None | 0.4425 | None | gnomAD-4.0.0 | 6.84466E-07 | |
22309 | 45 | D/G | 122 | rs1481781346 | 0.4425 | None | gnomAD-3.1.2 | 6.58E-06 | |
22309 | 45 | D/G | 122 | rs1481781346 | 0.4425 | None | gnomAD-4.0.0 | 6.5754E-06 | |
22309 | 45 | D/H | 122 | rs1204440058 | 0.4425 | None | gnomAD-2.1.1 | 4.03E-06 | |
22309 | 45 | D/H | 122 | rs1204440058 | 0.4425 | None | gnomAD-4.0.0 | 2.05342E-06 | |
22309 | 45 | D/N | 122 | rs1204440058 | 0.4425 | None | gnomAD-3.1.2 | 6.58E-06 | |
22309 | 45 | D/N | 122 | rs1204440058 | 0.4425 | None | gnomAD-4.0.0 | 2.47987E-06 | |
22309 | 45 | D/V | 122 | rs1481781346 | 0.4425 | None | gnomAD-4.0.0 | 4.10679E-06 | |
22310 | 46 | I/L | 123 | rs1315282961 | 0.2700 | None | gnomAD-2.1.1 | 3.19E-05 | |
22310 | 46 | I/L | 123 | rs1315282961 | 0.2700 | None | gnomAD-3.1.2 | 6.58E-06 | |
22310 | 46 | I/L | 123 | rs1315282961 | 0.2700 | None | gnomAD-4.0.0 | 6.57549E-06 | |
22313 | 49 | T/A | 130 | rs761874347 | 0.3861 | None | gnomAD-2.1.1 | 2.01E-05 | |
22313 | 49 | T/A | 130 | rs761874347 | 0.3861 | None | gnomAD-3.1.2 | 6.57E-06 | |
22313 | 49 | T/A | 130 | rs761874347 | 0.3861 | None | gnomAD-4.0.0 | 1.02558E-05 | |
22313 | 49 | T/P | 130 | rs761874347 | 0.3861 | None | gnomAD-3.1.2 | 6.57E-06 | |
22313 | 49 | T/P | 130 | rs761874347 | 0.3861 | None | gnomAD-4.0.0 | 6.57436E-06 | |
22313 | 49 | T/S | 130 | rs2047437261 | 0.3861 | None | gnomAD-4.0.0 | 1.59248E-06 | |
22314 | 50 | D/E | 131 | None | 0.5775 | None | gnomAD-4.0.0 | 1.59247E-06 | |
22314 | 50 | D/N | 131 | rs768380109 | 0.5775 | None | gnomAD-2.1.1 | 4.03E-06 | |
22314 | 50 | D/N | 131 | rs768380109 | 0.5775 | None | gnomAD-4.0.0 | 6.8444E-07 | |
22314 | 50 | D/Y | 131 | rs768380109 | 0.5775 | None | gnomAD-2.1.1 | 8.06E-06 | |
22314 | 50 | D/Y | 131 | rs768380109 | 0.5775 | None | gnomAD-3.1.2 | 4.6E-05 | |
22314 | 50 | D/Y | 131 | rs768380109 | 0.5775 | None | gnomAD-4.0.0 | 1.61168E-05 | |
22315 | 51 | F/L | 134 | rs746811214 | 0.5964 | None | gnomAD-4.0.0 | 2.05329E-06 | |
22315 | 51 | F/V | 134 | rs746811214 | 0.5964 | None | gnomAD-2.1.1 | 2.01E-05 | |
22315 | 51 | F/V | 134 | rs746811214 | 0.5964 | None | gnomAD-3.1.2 | 1.97E-05 | |
22315 | 51 | F/V | 134 | rs746811214 | 0.5964 | None | gnomAD-4.0.0 | 1.11583E-05 | |
22316 | 52 | D/E | 135 | None | 0.2418 | None | gnomAD-4.0.0 | 6.84438E-07 | |
22316 | 52 | D/N | 135 | rs948813723 | 0.2418 | None | gnomAD-3.1.2 | 1.97E-05 | |
22316 | 52 | D/N | 135 | rs948813723 | 0.2418 | None | gnomAD-4.0.0 | 8.67904E-06 | |
22317 | 53 | T/A | 136 | None | 0.1024 | None | gnomAD-4.0.0 | 6.84426E-07 | |
22317 | 53 | T/P | 136 | None | 0.1024 | None | gnomAD-4.0.0 | 6.84426E-07 | |
22317 | 53 | T/S | 136 | None | 0.1024 | None | gnomAD-4.0.0 | 1.59248E-06 | |
22318 | 54 | F/L | 137 | rs1282369228 | 0.2577 | None | gnomAD-2.1.1 | 8.06E-06 | |
22318 | 54 | F/L | 137 | rs1282369228 | 0.2577 | None | gnomAD-3.1.2 | 6.58E-06 | |
22318 | 54 | F/L | 137 | rs1282369228 | 0.2577 | None | gnomAD-4.0.0 | 3.09963E-06 | |
22318 | 54 | F/S | 137 | None | 0.2577 | None | gnomAD-4.0.0 | 4.77734E-06 | |
22319 | 55 | L/V | 138 | None | 0.0820 | None | gnomAD-4.0.0 | 1.59248E-06 | |
22320 | 56 | R/C | 139 | rs772361876 | 0.3955 | None | gnomAD-2.1.1 | 2.01E-05 | |
22320 | 56 | R/C | 139 | rs772361876 | 0.3955 | None | gnomAD-3.1.2 | 6.58E-06 | |
22320 | 56 | R/C | 139 | rs772361876 | 0.3955 | None | gnomAD-4.0.0 | 1.92173E-05 | |
22320 | 56 | R/H | 139 | rs771424865 | 0.3955 | None | gnomAD-2.1.1 | 3.93E-05 | |
22320 | 56 | R/H | 139 | rs771424865 | 0.3955 | None | gnomAD-3.1.2 | 4.6E-05 | |
22320 | 56 | R/H | 139 | rs771424865 | 0.3955 | None | gnomAD-4.0.0 | 2.72773E-05 | |
22320 | 56 | R/L | 139 | None | 0.3955 | None | gnomAD-4.0.0 | 1.3689E-06 | |
22322 | 58 | E/G | 141 | None | 0.4656 | None | gnomAD-4.0.0 | 1.20033E-06 | |
22323 | 59 | N/I | 143 | None | 0.7062 | None | gnomAD-4.0.0 | 1.20036E-06 | |
22324 | 60 | V/M | 144 | rs2154176354 | 0.0961 | None | gnomAD-4.0.0 | 1.36885E-06 | |
22325 | 61 | N/S | 145 | None | 0.2701 | None | gnomAD-4.0.0 | 1.5924E-06 | |
22326 | 62 | K/Q | 146 | None | 0.4819 | None | gnomAD-4.0.0 | 1.59239E-06 | |
22326 | 62 | K/R | 146 | rs202125813 | 0.4819 | None | gnomAD-2.1.1 | 4.93463E-04 | |
22326 | 62 | K/R | 146 | rs202125813 | 0.4819 | None | gnomAD-3.1.2 | 1.63049E-03 | |
22326 | 62 | K/R | 146 | rs202125813 | 0.4819 | None | 1000 genomes | 9.98403E-04 | |
22326 | 62 | K/R | 146 | rs202125813 | 0.4819 | None | gnomAD-4.0.0 | 3.01865E-04 | |
22327 | 63 | Y/C | 148 | rs757701692 | 0.6662 | None | gnomAD-2.1.1 | 4.03E-06 | |
22327 | 63 | Y/C | 148 | rs757701692 | 0.6662 | None | gnomAD-4.0.0 | 1.59235E-06 | |
22328 | 64 | D/N | 149 | None | 0.1626 | None | gnomAD-4.0.0 | 1.59242E-06 | |
22328 | 64 | D/V | 149 | rs749871897 | 0.1626 | None | gnomAD-2.1.1 | 4.03E-06 | |
22328 | 64 | D/V | 149 | rs749871897 | 0.1626 | None | gnomAD-4.0.0 | 1.59243E-06 | |
22329 | 65 | A/E | 151 | rs2047425169 | 0.2202 | None | gnomAD-4.0.0 | 6.84446E-07 | |
22329 | 65 | A/S | 151 | rs886055253 | 0.2202 | None | gnomAD-2.1.1 | 4.03E-06 | |
22329 | 65 | A/S | 151 | rs886055253 | 0.2202 | None | gnomAD-4.0.0 | 6.84437E-07 | |
22329 | 65 | A/T | 151 | rs886055253 | 0.2202 | None | gnomAD-2.1.1 | 4.03E-06 | |
22329 | 65 | A/T | 151 | rs886055253 | 0.2202 | None | gnomAD-4.0.0 | 5.4755E-06 | |
22332 | 68 | Y/C | 154 | rs1481543528 | 0.1585 | None | gnomAD-4.0.0 | 1.59242E-06 | |
22332 | 68 | Y/H | 154 | None | 0.1585 | None | gnomAD-4.0.0 | 1.36885E-06 | |
22332 | 68 | Y/S | 154 | rs1481543528 | 0.1585 | None | gnomAD-2.1.1 | 4.03E-06 | |
22332 | 68 | Y/S | 154 | rs1481543528 | 0.1585 | None | gnomAD-4.0.0 | 1.59242E-06 | |
22333 | 69 | I/T | 155 | rs2154176318 | 0.2540 | None | gnomAD-4.0.0 | 1.59245E-06 | |
22333 | 69 | I/V | 155 | rs753147042 | 0.2540 | None | gnomAD-2.1.1 | 4.03E-06 | |
22333 | 69 | I/V | 155 | rs753147042 | 0.2540 | None | gnomAD-4.0.0 | 1.59244E-06 | |
22334 | 70 | L/S | 156 | rs758106978 | 0.0917 | None | gnomAD-2.1.1 | 2.5E-05 | |
22334 | 70 | L/S | 156 | rs758106978 | 0.0917 | None | gnomAD-3.1.2 | 6.57E-06 | |
22334 | 70 | L/S | 156 | rs758106978 | 0.0917 | None | gnomAD-4.0.0 | 3.71944E-06 | |
22334 | 70 | L/V | 156 | rs766103894 | 0.0917 | None | gnomAD-2.1.1 | 4.03E-06 | |
22334 | 70 | L/V | 156 | rs766103894 | 0.0917 | None | gnomAD-3.1.2 | 6.57E-06 | |
22334 | 70 | L/V | 156 | rs766103894 | 0.0917 | None | gnomAD-4.0.0 | 4.3393E-06 | |
22335 | 71 | T/I | 157 | None | 0.1670 | None | gnomAD-4.0.0 | 1.59251E-06 | |
22336 | 72 | L/P | 158 | None | 0.1809 | None | gnomAD-4.0.0 | 3.4222E-06 | |
22337 | 73 | E/K | 159 | rs764858373 | 0.4606 | None | gnomAD-2.1.1 | 4.03E-06 | |
22338 | 74 | N/K | 161 | rs761241302 | 0.1851 | None | gnomAD-2.1.1 | 5.01E-05 | |
22338 | 74 | N/K | 161 | rs761241302 | 0.1851 | None | gnomAD-3.1.2 | 5.26E-05 | |
22338 | 74 | N/K | 161 | rs761241302 | 0.1851 | None | gnomAD-4.0.0 | 8.18319E-05 | |
22340 | 76 | C/R | 163 | None | 0.6291 | None | gnomAD-4.0.0 | 1.20036E-06 | |
22341 | 77 | G/D | 164 | rs2047417746 | 0.3720 | None | gnomAD-3.1.2 | 6.58E-06 | |
22341 | 77 | G/D | 164 | rs2047417746 | 0.3720 | None | gnomAD-4.0.0 | 6.57687E-06 | |
22341 | 77 | G/S | 164 | rs554588683 | 0.3720 | None | gnomAD-2.1.1 | 8.06E-06 | |
22341 | 77 | G/S | 164 | rs554588683 | 0.3720 | None | gnomAD-4.0.0 | 1.0952E-05 | |
22343 | 79 | K/N | 166 | None | 0.5213 | None | gnomAD-4.0.0 | 1.20037E-06 | |
22344 | 80 | E/D | 168 | rs1022112057 | 0.4196 | None | gnomAD-4.0.0 | 1.59273E-06 | |
22346 | 82 | T/I | 171 | None | 0.4745 | None | gnomAD-4.0.0 | 6.84524E-07 | |
22346 | 82 | T/N | 171 | rs1283475494 | 0.4745 | None | gnomAD-2.1.1 | 8.06E-06 | |
22346 | 82 | T/N | 171 | rs1283475494 | 0.4745 | None | gnomAD-4.0.0 | 2.05357E-06 | |
22347 | 83 | I/T | 172 | None | 0.1692 | None | gnomAD-4.0.0 | 9.60368E-06 | |
22348 | 84 | V/A | 173 | None | 0.3354 | None | gnomAD-4.0.0 | 2.05386E-06 | |
22348 | 84 | V/I | 173 | rs776484491 | 0.3354 | None | gnomAD-2.1.1 | 7.16E-06 | |
22348 | 84 | V/I | 173 | rs776484491 | 0.3354 | None | gnomAD-3.1.2 | 6.58E-06 | |
22348 | 84 | V/I | 173 | rs776484491 | 0.3354 | None | gnomAD-4.0.0 | 3.84758E-06 | |
22349 | 85 | V/A | 174 | None | 0.1257 | None | gnomAD-4.0.0 | 1.59393E-06 | |
22350 | 86 | K/Q | 175 | rs1370592733 | 0.5411 | None | gnomAD-2.1.1 | 4.04E-06 | |
22350 | 86 | K/Q | 175 | rs1370592733 | 0.5411 | None | gnomAD-3.1.2 | 1.32E-05 | |
22350 | 86 | K/Q | 175 | rs1370592733 | 0.5411 | None | gnomAD-4.0.0 | 3.72098E-06 | |
22351 | 87 | V/L | 177 | rs764048936 | 0.1852 | None | gnomAD-2.1.1 | 8.08E-06 | |
22351 | 87 | V/L | 177 | rs764048936 | 0.1852 | None | gnomAD-3.1.2 | 6.58E-06 | |
22351 | 87 | V/L | 177 | rs764048936 | 0.1852 | None | gnomAD-4.0.0 | 7.44266E-06 |