10 | 20 | 30 | 40 | 50 | 60 | 70 | 80 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
P | D | I | V | L | Y | P | E | P | V | R | V | L | E | G | E | T | A | R | F | R | C | R | V | T | G | Y | P | Q | P | K | V | N | W | Y | L | N | G | Q | L | I | R | K | S | K | R | F | R | V | R | Y | D | G | I | H | Y | L | D | I | V | D | C | K | S | Y | D | T | G | E | V | K | V | T | A | E | N | P | E | G | V | I | E | H | K | V | K | L | E | I |
Pin SAV |
Position |
Domain position |
SAV |
Structural Position |
RS |
Q(SASA) |
Disease |
Source |
MAF |
---|---|---|---|---|---|---|---|---|---|
1841 | 1 | P/A | 1 | rs2092223128 | 0.1778 | None | gnomAD-4.0.0 | 1.59142E-06 | |
1841 | 1 | P/S | 1 | None | 0.1778 | None | gnomAD-4.0.0 | 1.59142E-06 | |
1841 | 1 | P/T | 1 | None | 0.1778 | None | gnomAD-4.0.0 | 1.59142E-06 | |
1842 | 2 | D/H | 2 | None | 0.4007 | None | gnomAD-4.0.0 | 6.84204E-07 | |
1842 | 2 | D/N | 2 | rs1469586209 | 0.4007 | None | gnomAD-2.1.1 | 3.98E-06 | |
1842 | 2 | D/N | 2 | rs1469586209 | 0.4007 | None | gnomAD-4.0.0 | 6.84204E-07 | |
1843 | 3 | I/T | 3 | None | 0.0820 | None | gnomAD-4.0.0 | 1.59108E-06 | |
1843 | 3 | I/V | 3 | None | 0.0820 | None | gnomAD-4.0.0 | 6.00161E-06 | |
1844 | 4 | V/D | 4 | None | 0.3860 | None | gnomAD-4.0.0 | 1.59103E-06 | |
1844 | 4 | V/F | 4 | rs769474668 | 0.3860 | None | gnomAD-2.1.1 | 3.98E-06 | |
1844 | 4 | V/F | 4 | rs769474668 | 0.3860 | None | gnomAD-3.1.2 | 3.29E-05 | |
1844 | 4 | V/F | 4 | rs769474668 | 0.3860 | None | gnomAD-4.0.0 | 1.73501E-05 | |
1846 | 6 | Y/C | 7 | rs746592442 | 0.3688 | None | gnomAD-2.1.1 | 3.98E-06 | |
1846 | 6 | Y/C | 7 | rs746592442 | 0.3688 | None | gnomAD-4.0.0 | 1.59093E-06 | |
1847 | 7 | P/S | 8 | rs138778559 | 0.2676 | None | gnomAD-2.1.1 | 3.98E-06 | |
1847 | 7 | P/S | 8 | rs138778559 | 0.2676 | None | gnomAD-4.0.0 | 1.59104E-06 | |
1849 | 9 | P/A | 11 | rs771747683 | 0.5932 | None | gnomAD-2.1.1 | 1.19E-05 | |
1849 | 9 | P/A | 11 | rs771747683 | 0.5932 | None | gnomAD-4.0.0 | 3.42084E-06 | |
1851 | 11 | R/T | 14 | None | 0.6468 | None | gnomAD-4.0.0 | 9.60257E-06 | |
1852 | 12 | V/I | 16 | None | 0.1084 | None | gnomAD-4.0.0 | 6.84119E-07 | |
1853 | 13 | L/F | 18 | rs778377360 | 0.4886 | None | gnomAD-2.1.1 | 3.98E-06 | |
1853 | 13 | L/F | 18 | rs778377360 | 0.4886 | None | gnomAD-4.0.0 | 1.36824E-06 | |
1853 | 13 | L/P | 18 | None | 0.4886 | None | gnomAD-4.0.0 | 3.18144E-06 | |
1853 | 13 | L/V | 18 | rs778377360 | 0.4886 | None | gnomAD-2.1.1 | 3.98E-06 | |
1853 | 13 | L/V | 18 | rs778377360 | 0.4886 | None | gnomAD-3.1.2 | 6.57E-06 | |
1853 | 13 | L/V | 18 | rs778377360 | 0.4886 | None | gnomAD-4.0.0 | 1.23922E-06 | |
1854 | 14 | E/D | 23 | rs571222694 | 0.3693 | None | gnomAD-2.1.1 | 3.98E-06 | |
1854 | 14 | E/D | 23 | rs571222694 | 0.3693 | None | gnomAD-3.1.2 | 6.57E-06 | |
1854 | 14 | E/D | 23 | rs571222694 | 0.3693 | None | 1000 genomes | 1.99681E-04 | |
1854 | 14 | E/D | 23 | rs571222694 | 0.3693 | None | gnomAD-4.0.0 | 6.5653E-06 | |
1854 | 14 | E/K | 23 | rs1443747233 | 0.3693 | None | gnomAD-2.1.1 | 3.98E-06 | |
1854 | 14 | E/K | 23 | rs1443747233 | 0.3693 | None | gnomAD-4.0.0 | 1.5907E-06 | |
1855 | 15 | G/E | 24 | rs753507549 | 0.2942 | None | gnomAD-2.1.1 | 3.54E-05 | |
1855 | 15 | G/E | 24 | rs753507549 | 0.2942 | None | gnomAD-3.1.2 | 1.31E-05 | |
1855 | 15 | G/E | 24 | rs753507549 | 0.2942 | None | gnomAD-4.0.0 | 1.28071E-05 | |
1856 | 16 | E/K | 25 | rs1315454944 | 0.2932 | None | gnomAD-3.1.2 | 6.57E-06 | |
1856 | 16 | E/K | 25 | rs1315454944 | 0.2932 | None | gnomAD-4.0.0 | 1.05332E-05 | |
1857 | 17 | T/N | 26 | None | 0.2766 | None | gnomAD-4.0.0 | 1.59067E-06 | |
1859 | 19 | R/M | 29 | rs777923620 | 0.4249 | None | gnomAD-2.1.1 | 7.96E-06 | |
1859 | 19 | R/M | 29 | rs777923620 | 0.4249 | None | gnomAD-4.0.0 | 1.59062E-06 | |
1859 | 19 | R/S | 29 | rs551538420 | 0.4249 | None | gnomAD-2.1.1 | 5.31E-05 | |
1859 | 19 | R/S | 29 | rs551538420 | 0.4249 | None | gnomAD-3.1.2 | 7.89E-05 | |
1859 | 19 | R/S | 29 | rs551538420 | 0.4249 | None | 1000 genomes | 1.99681E-04 | |
1859 | 19 | R/S | 29 | rs551538420 | 0.4249 | None | gnomAD-4.0.0 | 1.31342E-04 | |
1861 | 21 | R/C | 31 | rs532733393 | 0.4343 | None | gnomAD-2.1.1 | 6.01E-05 | |
1861 | 21 | R/C | 31 | rs532733393 | 0.4343 | None | gnomAD-3.1.2 | 3.94E-05 | |
1861 | 21 | R/C | 31 | rs532733393 | 0.4343 | None | 1000 genomes | 1.99681E-04 | |
1861 | 21 | R/C | 31 | rs532733393 | 0.4343 | None | gnomAD-4.0.0 | 3.5935E-05 | |
1861 | 21 | R/H | 31 | rs140914855 | 0.4343 | None | gnomAD-2.1.1 | 8.49E-05 | |
1861 | 21 | R/H | 31 | rs140914855 | 0.4343 | None | gnomAD-3.1.2 | 3.29E-05 | |
1861 | 21 | R/H | 31 | rs140914855 | 0.4343 | None | gnomAD-4.0.0 | 7.99232E-05 | |
1862 | 22 | C/G | 33 | rs2092215973 | 0.1116 | None | gnomAD-4.0.0 | 1.20032E-06 | |
1862 | 22 | C/S | 33 | None | 0.1116 | None | gnomAD-4.0.0 | 1.20032E-06 | |
1863 | 23 | R/K | 34 | None | 0.4587 | None | gnomAD-4.0.0 | 2.05225E-06 | |
1863 | 23 | R/S | 34 | rs763383772 | 0.4587 | None | gnomAD-2.1.1 | 3.98E-06 | |
1864 | 24 | V/I | 35 | rs2092215067 | 0.2055 | None | gnomAD-4.0.0 | 1.20032E-06 | |
1865 | 25 | T/A | 38 | rs2092214772 | 0.4196 | None | gnomAD-3.1.2 | 6.57E-06 | |
1865 | 25 | T/A | 38 | rs2092214772 | 0.4196 | None | gnomAD-4.0.0 | 2.02979E-06 | |
1866 | 26 | G/D | 40 | rs2092214175 | 0.3004 | None | gnomAD-4.0.0 | 8.20898E-06 | |
1868 | 28 | P/H | 42 | None | 0.3018 | None | gnomAD-2.1.1 | 3.98E-06 | |
1868 | 28 | P/H | 42 | None | 0.3018 | None | gnomAD-4.0.0 | 1.5906E-06 | |
1868 | 28 | P/L | 42 | rs773566945 | 0.3018 | None | gnomAD-4.0.0 | 1.5906E-06 | |
1868 | 28 | P/R | 42 | rs773566945 | 0.3018 | None | gnomAD-2.1.1 | 3.98E-06 | |
1868 | 28 | P/R | 42 | rs773566945 | 0.3018 | None | gnomAD-4.0.0 | 1.5906E-06 | |
1869 | 29 | Q/K | 43 | None | 0.7175 | None | gnomAD-4.0.0 | 1.59055E-06 | |
1869 | 29 | Q/R | 43 | rs770347404 | 0.7175 | None | gnomAD-2.1.1 | 3.58E-05 | |
1869 | 29 | Q/R | 43 | rs770347404 | 0.7175 | None | gnomAD-3.1.2 | 1.31E-05 | |
1869 | 29 | Q/R | 43 | rs770347404 | 0.7175 | None | gnomAD-4.0.0 | 1.66462E-05 | |
1870 | 30 | P/S | 44 | None | 0.1444 | None | gnomAD-4.0.0 | 1.20032E-06 | |
1871 | 31 | K/N | 45 | None | 0.8524 | None | gnomAD-4.0.0 | 2.40064E-06 | |
1872 | 32 | V/L | 46 | None | 0.2948 | None | gnomAD-4.0.0 | 2.40064E-06 | |
1873 | 33 | N/S | 47 | rs762273184 | 0.8214 | None | gnomAD-2.1.1 | 3.98E-06 | |
1873 | 33 | N/S | 47 | rs762273184 | 0.8214 | None | gnomAD-3.1.2 | 6.57E-06 | |
1873 | 33 | N/S | 47 | rs762273184 | 0.8214 | None | gnomAD-4.0.0 | 6.5684E-06 | |
1874 | 34 | W/G | 48 | rs2092211950 | 0.2218 | None | gnomAD-3.1.2 | 6.57E-06 | |
1874 | 34 | W/G | 48 | rs2092211950 | 0.2218 | None | gnomAD-4.0.0 | 6.56927E-06 | |
1874 | 34 | W/R | 48 | None | 0.2218 | None | gnomAD-4.0.0 | 1.59051E-06 | |
1874 | 34 | W/S | 48 | None | 0.2218 | None | gnomAD-4.0.0 | 3.18105E-06 | |
1876 | 36 | L/F | 50 | rs1419821413 | 0.1602 | None | gnomAD-4.0.0 | 6.84073E-07 | |
1876 | 36 | L/H | 50 | rs771632040 | 0.1602 | None | gnomAD-2.1.1 | 7.96E-06 | |
1876 | 36 | L/H | 50 | rs771632040 | 0.1602 | None | gnomAD-4.0.0 | 2.73628E-06 | |
1876 | 36 | L/V | 50 | rs1419821413 | 0.1602 | None | gnomAD-2.1.1 | 7.96E-06 | |
1876 | 36 | L/V | 50 | rs1419821413 | 0.1602 | None | gnomAD-3.1.2 | 1.31E-05 | |
1876 | 36 | L/V | 50 | rs1419821413 | 0.1602 | None | gnomAD-4.0.0 | 3.09784E-06 | |
1877 | 37 | N/I | 51 | rs1554006798 | 0.4638 | None | gnomAD-4.0.0 | 6.36207E-06 | |
1878 | 38 | G/E | 52 | rs745311218 | 0.4542 | None | gnomAD-2.1.1 | 1.06E-05 | |
1878 | 38 | G/E | 52 | rs745311218 | 0.4542 | None | gnomAD-3.1.2 | 1.31E-05 | |
1878 | 38 | G/E | 52 | rs745311218 | 0.4542 | None | gnomAD-4.0.0 | 1.30108E-05 | |
1879 | 39 | Q/R | 55 | rs1237628152 | 0.8413 | None | gnomAD-2.1.1 | 3.98E-06 | |
1879 | 39 | Q/R | 55 | rs1237628152 | 0.8413 | None | gnomAD-3.1.2 | 1.31E-05 | |
1879 | 39 | Q/R | 55 | rs1237628152 | 0.8413 | None | gnomAD-4.0.0 | 3.84135E-06 | |
1880 | 40 | L/F | 56 | rs2092208587 | 0.6586 | None | gnomAD-4.0.0 | 1.20032E-06 | |
1881 | 41 | I/T | 58 | rs1426496038 | 0.1606 | None | gnomAD-2.1.1 | 3.18E-05 | |
1881 | 41 | I/T | 58 | rs1426496038 | 0.1606 | None | gnomAD-3.1.2 | 1.31E-05 | |
1881 | 41 | I/T | 58 | rs1426496038 | 0.1606 | None | gnomAD-4.0.0 | 1.3143E-05 | |
1882 | 42 | R/C | 59 | rs397517658 | 0.7454 | None | gnomAD-2.1.1 | 2.12E-05 | |
1882 | 42 | R/C | 59 | rs397517658 | 0.7454 | None | gnomAD-3.1.2 | 2.63E-05 | |
1882 | 42 | R/C | 59 | rs397517658 | 0.7454 | None | gnomAD-4.0.0 | 2.72615E-05 | |
1882 | 42 | R/H | 59 | rs374605213 | 0.7454 | None | gnomAD-2.1.1 | 6.37E-05 | |
1882 | 42 | R/H | 59 | rs374605213 | 0.7454 | None | gnomAD-3.1.2 | 1.77424E-04 | |
1882 | 42 | R/H | 59 | rs374605213 | 0.7454 | None | gnomAD-4.0.0 | 5.20447E-05 | |
1882 | 42 | R/S | 59 | None | 0.7454 | None | gnomAD-4.0.0 | 6.84077E-07 | |
1883 | 43 | K/T | 70 | None | 0.7589 | None | gnomAD-4.0.0 | 1.20032E-06 | |
1884 | 44 | S/N | 73 | rs749151809 | 0.2394 | None | gnomAD-2.1.1 | 1.19E-05 | |
1884 | 44 | S/N | 73 | rs749151809 | 0.2394 | None | gnomAD-4.0.0 | 4.10444E-06 | |
1884 | 44 | S/T | 73 | rs749151809 | 0.2394 | None | gnomAD-2.1.1 | 3.18E-05 | |
1884 | 44 | S/T | 73 | rs749151809 | 0.2394 | None | gnomAD-3.1.2 | 1.31E-05 | |
1884 | 44 | S/T | 73 | rs749151809 | 0.2394 | None | gnomAD-4.0.0 | 1.85871E-06 | |
1889 | 49 | V/F | 123 | rs141105443 | 0.2252 | None | gnomAD-2.1.1 | 4.6E-05 | |
1889 | 49 | V/F | 123 | rs141105443 | 0.2252 | None | gnomAD-3.1.2 | 5.26E-05 | |
1889 | 49 | V/F | 123 | rs141105443 | 0.2252 | None | gnomAD-4.0.0 | 1.20814E-04 | |
1889 | 49 | V/I | 123 | None | 0.2252 | None | gnomAD-4.0.0 | 6.8407E-07 | |
1890 | 50 | R/C | 125 | rs146496197 | 0.2895 | None | gnomAD-2.1.1 | 4.07244E-04 | |
1890 | 50 | R/C | 125 | rs146496197 | 0.2895 | None | gnomAD-3.1.2 | 1.03209E-03 | |
1890 | 50 | R/C | 125 | rs146496197 | 0.2895 | None | 1000 genomes | 5.99042E-04 | |
1890 | 50 | R/C | 125 | rs146496197 | 0.2895 | None | gnomAD-4.0.0 | 3.25884E-04 | |
1890 | 50 | R/H | 125 | rs370027329 | 0.2895 | None | gnomAD-2.1.1 | 1.06E-05 | |
1890 | 50 | R/H | 125 | rs370027329 | 0.2895 | None | gnomAD-3.1.2 | 1.31E-05 | |
1890 | 50 | R/H | 125 | rs370027329 | 0.2895 | None | gnomAD-4.0.0 | 7.43487E-06 | |
1890 | 50 | R/P | 125 | rs370027329 | 0.2895 | None | gnomAD-2.1.1 | 3.98E-06 | |
1890 | 50 | R/P | 125 | rs370027329 | 0.2895 | None | gnomAD-4.0.0 | 6.84068E-07 | |
1891 | 51 | Y/C | 127 | rs547305291 | 0.4609 | None | gnomAD-2.1.1 | 4.38E-05 | |
1891 | 51 | Y/C | 127 | rs547305291 | 0.4609 | None | gnomAD-3.1.2 | 3.28E-05 | |
1891 | 51 | Y/C | 127 | rs547305291 | 0.4609 | None | 1000 genomes | 5.99042E-04 | |
1891 | 51 | Y/C | 127 | rs547305291 | 0.4609 | None | gnomAD-4.0.0 | 3.65513E-05 | |
1893 | 53 | G/A | 134 | None | 0.2299 | None | gnomAD-4.0.0 | 1.36815E-06 | |
1893 | 53 | G/D | 134 | None | 0.2299 | None | gnomAD-4.0.0 | 2.05223E-06 | |
1893 | 53 | G/S | 134 | rs1380250256 | 0.2299 | None | gnomAD-2.1.1 | 3.98E-06 | |
1893 | 53 | G/S | 134 | rs1380250256 | 0.2299 | None | gnomAD-4.0.0 | 1.36815E-06 | |
1894 | 54 | I/V | 135 | rs751529942 | 0.2023 | None | gnomAD-2.1.1 | 7.97E-06 | |
1894 | 54 | I/V | 135 | rs751529942 | 0.2023 | None | gnomAD-4.0.0 | 6.36215E-06 | |
1895 | 55 | H/P | 136 | rs766694270 | 0.2037 | None | gnomAD-2.1.1 | 2.79E-05 | |
1895 | 55 | H/P | 136 | rs766694270 | 0.2037 | None | gnomAD-4.0.0 | 1.11337E-05 | |
1895 | 55 | H/Y | 136 | rs794729577 | 0.2037 | None | gnomAD-2.1.1 | 7.97E-06 | |
1895 | 55 | H/Y | 136 | rs794729577 | 0.2037 | None | gnomAD-3.1.2 | 1.31E-05 | |
1895 | 55 | H/Y | 136 | rs794729577 | 0.2037 | None | gnomAD-4.0.0 | 1.23917E-05 | |
1897 | 57 | L/Q | 138 | rs1299766514 | 0.0467 | None | gnomAD-2.1.1 | 3.98E-06 | |
1897 | 57 | L/Q | 138 | rs1299766514 | 0.0467 | None | gnomAD-4.0.0 | 1.5905E-06 | |
1899 | 59 | I/T | 140 | None | 0.0650 | None | gnomAD-4.0.0 | 1.20032E-06 | |
1899 | 59 | I/V | 140 | rs878986033 | 0.0650 | None | gnomAD-2.1.1 | 1.59E-05 | |
1899 | 59 | I/V | 140 | rs878986033 | 0.0650 | None | gnomAD-3.1.2 | 2.63E-05 | |
1899 | 59 | I/V | 140 | rs878986033 | 0.0650 | None | gnomAD-4.0.0 | 4.33691E-06 | |
1900 | 60 | V/G | 141 | rs878931921 | 0.2300 | None | gnomAD-4.0.0 | 1.20032E-06 | |
1900 | 60 | V/L | 141 | None | 0.2300 | None | gnomAD-4.0.0 | 1.02611E-05 | |
1900 | 60 | V/M | 141 | rs750823043 | 0.2300 | None | gnomAD-2.1.1 | 2.48E-05 | |
1900 | 60 | V/M | 141 | rs750823043 | 0.2300 | None | gnomAD-3.1.2 | 3.29E-05 | |
1900 | 60 | V/M | 141 | rs750823043 | 0.2300 | None | gnomAD-4.0.0 | 2.47831E-05 | |
1901 | 61 | D/G | 143 | rs1414147349 | 0.4431 | None | gnomAD-2.1.1 | 7.97E-06 | |
1901 | 61 | D/G | 143 | rs1414147349 | 0.4431 | None | gnomAD-3.1.2 | 1.31E-05 | |
1901 | 61 | D/G | 143 | rs1414147349 | 0.4431 | None | gnomAD-4.0.0 | 9.29337E-06 | |
1901 | 61 | D/N | 143 | None | 0.4431 | None | gnomAD-4.0.0 | 1.5905E-06 | |
1905 | 65 | Y/C | 148 | rs1265838947 | 0.5059 | None | gnomAD-2.1.1 | 3.98E-06 | |
1905 | 65 | Y/C | 148 | rs1265838947 | 0.5059 | None | gnomAD-4.0.0 | 1.59051E-06 | |
1905 | 65 | Y/H | 148 | rs1477069650 | 0.5059 | None | gnomAD-2.1.1 | 3.98E-06 | |
1905 | 65 | Y/H | 148 | rs1477069650 | 0.5059 | None | gnomAD-4.0.0 | 2.53106E-05 | |
1906 | 66 | D/V | 149 | rs1490334415 | 0.0935 | None | gnomAD-2.1.1 | 3.98E-06 | |
1906 | 66 | D/V | 149 | rs1490334415 | 0.0935 | None | gnomAD-4.0.0 | 1.59052E-06 | |
1906 | 66 | D/Y | 149 | rs1194783923 | 0.0935 | None | gnomAD-2.1.1 | 3.98E-06 | |
1906 | 66 | D/Y | 149 | rs1194783923 | 0.0935 | None | gnomAD-4.0.0 | 1.59052E-06 | |
1907 | 67 | T/I | 151 | None | 0.3185 | None | gnomAD-4.0.0 | 1.20032E-06 | |
1908 | 68 | G/D | 152 | None | 0.2461 | None | gnomAD-4.0.0 | 3.60097E-06 | |
1908 | 68 | G/R | 152 | None | 0.2461 | None | gnomAD-4.0.0 | 6.84069E-07 | |
1908 | 68 | G/S | 152 | rs964474432 | 0.2461 | None | gnomAD-3.1.2 | 1.31E-05 | |
1908 | 68 | G/S | 152 | rs964474432 | 0.2461 | None | gnomAD-4.0.0 | 4.95651E-06 | |
1910 | 70 | V/A | 154 | rs1322379803 | 0.1565 | None | gnomAD-2.1.1 | 3.98E-06 | |
1910 | 70 | V/A | 154 | rs1322379803 | 0.1565 | None | gnomAD-4.0.0 | 6.84075E-07 | |
1910 | 70 | V/E | 154 | None | 0.1565 | None | gnomAD-4.0.0 | 6.84075E-07 | |
1910 | 70 | V/L | 154 | rs765618372 | 0.1565 | None | gnomAD-2.1.1 | 3.98E-06 | |
1910 | 70 | V/L | 154 | rs765618372 | 0.1565 | None | gnomAD-4.0.0 | 1.59052E-06 | |
1910 | 70 | V/M | 154 | rs765618372 | 0.1565 | None | gnomAD-2.1.1 | 3.98E-06 | |
1910 | 70 | V/M | 154 | rs765618372 | 0.1565 | None | gnomAD-4.0.0 | 3.18104E-06 | |
1911 | 71 | K/T | 155 | rs1473622038 | 0.1494 | None | gnomAD-3.1.2 | 6.57E-06 | |
1911 | 71 | K/T | 155 | rs1473622038 | 0.1494 | None | gnomAD-4.0.0 | 6.56978E-06 | |
1913 | 73 | T/I | 157 | None | 0.3284 | None | gnomAD-4.0.0 | 1.59052E-06 | |
1913 | 73 | T/N | 157 | rs1306092689 | 0.3284 | None | gnomAD-2.1.1 | 3.19E-05 | |
1913 | 73 | T/N | 157 | rs1306092689 | 0.3284 | None | gnomAD-3.1.2 | 6.57E-06 | |
1913 | 73 | T/N | 157 | rs1306092689 | 0.3284 | None | gnomAD-4.0.0 | 6.57333E-06 | |
1913 | 73 | T/S | 157 | rs1306092689 | 0.3284 | None | gnomAD-3.1.2 | 6.57E-06 | |
1913 | 73 | T/S | 157 | rs1306092689 | 0.3284 | None | gnomAD-4.0.0 | 6.57333E-06 | |
1914 | 74 | A/T | 158 | rs118161093 | 0.0961 | None | gnomAD-2.1.1 | 1.38036E-04 | |
1914 | 74 | A/T | 158 | rs118161093 | 0.0961 | None | gnomAD-3.1.2 | 7.23E-05 | |
1914 | 74 | A/T | 158 | rs118161093 | 0.0961 | None | 1000 genomes | 3.99361E-04 | |
1914 | 74 | A/T | 158 | rs118161093 | 0.0961 | None | gnomAD-4.0.0 | 5.01811E-05 | |
1914 | 74 | A/V | 158 | rs374203813 | 0.0961 | None | gnomAD-2.1.1 | 3.58E-05 | |
1914 | 74 | A/V | 158 | rs374203813 | 0.0961 | None | gnomAD-3.1.2 | 3.29E-05 | |
1914 | 74 | A/V | 158 | rs374203813 | 0.0961 | None | 1000 genomes | 1.99681E-04 | |
1914 | 74 | A/V | 158 | rs374203813 | 0.0961 | None | gnomAD-4.0.0 | 2.29239E-05 | |
1915 | 75 | E/K | 159 | rs375388374 | 0.5316 | None | gnomAD-2.1.1 | 7.96E-06 | |
1915 | 75 | E/K | 159 | rs375388374 | 0.5316 | None | gnomAD-3.1.2 | 6.57E-06 | |
1915 | 75 | E/K | 159 | rs375388374 | 0.5316 | None | gnomAD-4.0.0 | 2.56104E-06 | |
1917 | 77 | P/T | 162 | None | 0.5708 | None | gnomAD-4.0.0 | 1.20032E-06 | |
1919 | 79 | G/D | 164 | None | 0.2613 | None | gnomAD-4.0.0 | 6.36207E-06 | |
1920 | 80 | V/M | 165 | rs773719613 | 0.4720 | None | gnomAD-2.1.1 | 3.98E-06 | |
1921 | 81 | I/V | 166 | rs879100565 | 0.1919 | None | gnomAD-2.1.1 | 7.08E-06 | |
1921 | 81 | I/V | 166 | rs879100565 | 0.1919 | None | gnomAD-3.1.2 | 1.31E-05 | |
1921 | 81 | I/V | 166 | rs879100565 | 0.1919 | None | gnomAD-4.0.0 | 1.54892E-05 | |
1922 | 82 | E/K | 168 | None | 0.3906 | None | gnomAD-4.0.0 | 6.84071E-07 | |
1922 | 82 | E/Q | 168 | rs1349924695 | 0.3906 | None | gnomAD-2.1.1 | 3.98E-06 | |
1922 | 82 | E/Q | 168 | rs1349924695 | 0.3906 | None | gnomAD-4.0.0 | 6.84071E-07 | |
1923 | 83 | H/Q | 169 | None | 0.2885 | None | gnomAD-4.0.0 | 1.36814E-06 | |
1923 | 83 | H/R | 169 | None | 0.2885 | None | gnomAD-4.0.0 | 3.18103E-06 | |
1923 | 83 | H/Y | 169 | None | 0.2885 | None | gnomAD-4.0.0 | 1.59051E-06 | |
1924 | 84 | K/E | 171 | rs1327562179 | 0.3333 | None | gnomAD-2.1.1 | 7.96E-06 | |
1924 | 84 | K/E | 171 | rs1327562179 | 0.3333 | None | gnomAD-4.0.0 | 3.42034E-06 | |
1924 | 84 | K/N | 171 | None | 0.3333 | None | gnomAD-4.0.0 | 1.5905E-06 | |
1925 | 85 | V/A | 172 | None | 0.4379 | None | gnomAD-4.0.0 | 3.18102E-06 | |
1925 | 85 | V/M | 172 | None | 0.4379 | None | gnomAD-4.0.0 | 1.20032E-06 | |
1927 | 87 | L/P | 174 | None | 0.0959 | None | gnomAD-4.0.0 | 1.59049E-06 | |
1929 | 89 | I/F | 177 | rs748917796 | 0.1558 | None | gnomAD-2.1.1 | 1.19E-05 | |
1929 | 89 | I/F | 177 | rs748917796 | 0.1558 | None | gnomAD-4.0.0 | 9.57695E-06 | |
1929 | 89 | I/T | 177 | None | 0.1558 | None | gnomAD-4.0.0 | 1.20032E-06 |